| Rank | Company | Total assets | Sector | Industry | Country | Exchange |
|---|---|---|---|---|---|---|
| 1901 | $93.5M | Technology | Information Technology Services | United States | Nasdaq | |
| 1902 | $93.4M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1903 | $93.4M | Technology | Information Technology Services | United States | Nasdaq | |
| 1904 | $93.0M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1905 | $92.3M | Healthcare | Medical Devices | United States | Nasdaq | |
| 1906 | $92.2M | Real Estate | Real Estate | United States | Nasdaq | |
| 1907 | $90.4M | Technology | Electronic Components | United States | Nasdaq | |
| 1908 | $90.2M | Real Estate | Real Estate | United States | Nasdaq | |
| 1909 | $89.4M | Technology | Semiconductors | United States | Nasdaq | |
| 1910 | $89.3M | Basic Materials | Industrial Minerals | United States | Nasdaq | |
| 1911 | $89.3M | Financial Services | Financial Conglomerates | United States | Nasdaq | |
| 1912 | $88.9M | Utilities | Utilities | United States | Nasdaq | |
| 1913 | $88.6M | Technology | Electronic Components | United States | Nasdaq | |
| 1914 | $88.1M | Technology | Information Technology Services | United States | Nasdaq | |
| 1915 | $87.7M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1916 | $87.6M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1917 | $87.4M | Consumer Cyclical | Apparel & Textiles | United States | Nasdaq | |
| 1918 | $86.9M | Real Estate | REIT | United States | Nasdaq | |
| 1919 | $86.7M | Healthcare | Medical Devices | United States | Nasdaq | |
| 1920 | $86.7M | Healthcare | Healthcare Providers | United States | Nasdaq | |
| 1921 | $86.7M | Basic Materials | Building Materials & Metals | United States | Nasdaq | |
| 1922 | $86.7M | Consumer Cyclical | Internet Retail | United States | Nasdaq | |
| 1923 | $86.3M | Basic Materials | Chemicals | United States | Nasdaq | |
| 1924 | $86.2M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1925 | $85.2M | Basic Materials | Chemicals | United States | Nasdaq | |
| 1926 | $85.2M | Industrials | Industrial Machinery | United States | Nasdaq | |
| 1927 | $84.4M | Basic Materials | Agriculture | United States | Nasdaq | |
| 1928 | $84.3M | Consumer Defensive | Education | United States | Nasdaq | |
| 1929 | $82.5M | Industrials | Wholesale Distribution | United States | Nasdaq | |
| 1930 | $82.1M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1931 | $82.0M | Consumer Defensive | Packaged Foods | United States | Nasdaq | |
| 1932 | $82.0M | Healthcare | Medical Devices | United States | Nasdaq | |
| 1933 | $81.7M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1934 | $81.6M | Consumer Cyclical | Rubber & Plastics | United States | Nasdaq | |
| 1935 | $81.5M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1936 | $81.0M | Industrials | Industrial Machinery | United States | Nasdaq | |
| 1937 | $80.5M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1938 | $80.2M | Consumer Cyclical | Restaurants | United States | Nasdaq | |
| 1939 | $80.0M | Technology | Electronic Components | United States | Nasdaq | |
| 1940 | $79.5M | Industrials | Fabricated Metal Products | United States | Nasdaq | |
| 1941 | $79.5M | Technology | Semiconductors | United States | Nasdaq | |
| 1942 | $78.3M | Technology | Information Technology Services | United States | Nasdaq | |
| 1943 | $78.0M | Technology | Information Technology Services | United States | Nasdaq | |
| 1944 | $77.9M | Technology | Semiconductors | United States | Nasdaq | |
| 1945 | $77.8M | Technology | Software | United States | Nasdaq | |
| 1946 | $76.9M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1947 | $76.6M | Consumer Cyclical | Transportation Equipment | United States | Nasdaq | |
| 1948 | $76.3M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1949 | $76.3M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 1950 | $75.8M | Healthcare | Biotechnology | United States | Nasdaq | |
| 1951 | $75.7M | Industrials | Wholesale Distribution | United States | Nasdaq | |
| 1952 | $75.1M | Technology | Information Technology Services | United States | Nasdaq | |
| 1953 | $75.0M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1954 | $74.9M | Technology | Information Technology Services | United States | Nasdaq | |
| 1955 | $74.5M | Healthcare | Medical Devices | United States | Nasdaq | |
| 1956 | $74.3M | Technology | Electronic Components | United States | Nasdaq | |
| 1957 | $74.1M | Technology | Electronic Components | United States | Nasdaq | |
| 1958 | $73.7M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1959 | $73.6M | Technology | Information Technology Services | United States | Nasdaq | |
| 1960 | $73.4M | Real Estate | Real Estate | United States | Nasdaq | |
| 1961 | $73.4M | Healthcare | Medical Devices | United States | Nasdaq | |
| 1962 | $73.0M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1963 | $72.2M | Industrials | Industrial Machinery | United States | Nasdaq | |
| 1964 | $72.1M | Industrials | Transportation & Logistics | United States | Nasdaq | |
| 1965 | $72.1M | Technology | Electronic Components | United States | Nasdaq | |
| 1966 | $72.1M | Consumer Defensive | Grocery Stores | United States | Nasdaq | |
| 1967 | $72.0M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1968 | $71.2M | Financial Services | Financial Conglomerates | United States | Nasdaq | |
| 1969 | $70.9M | Technology | Information Technology Services | United States | Nasdaq | |
| 1970 | $70.8M | Technology | Information Technology Services | United States | Nasdaq | |
| 1971 | $70.4M | Industrials | Specialty Business Services | United States | Nasdaq | |
| 1972 | $70.3M | Technology | Electronic Components | United States | Nasdaq | |
| 1973 | $70.0M | Industrials | Engineering & Construction | United States | Nasdaq | |
| 1974 | $69.8M | Healthcare | Biotechnology | United States | Nasdaq | |
| 1975 | $69.7M | Healthcare | Medical Devices | United States | Nasdaq | |
| 1976 | $69.6M | Healthcare | Medical Devices | United States | Nasdaq | |
| 1977 | $69.3M | Industrials | Industrial Machinery | United States | Nasdaq | |
| 1978 | $69.1M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 1979 | $69.1M | Financial Services | Banks | United States | Nasdaq | |
| 1980 | $69.0M | Healthcare | Pharmaceutical Retailers | United States | Nasdaq | |
| 1981 | $68.9M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 1982 | $68.5M | Consumer Cyclical | Apparel & Textiles | United States | Nasdaq | |
| 1983 | $68.4M | Consumer Cyclical | Auto Manufacturers | United States | Nasdaq | |
| 1984 | $68.4M | Technology | Semiconductors | United States | Nasdaq | |
| 1985 | $68.0M | Basic Materials | Industrial Minerals | United States | Nasdaq | |
| 1986 | $67.8M | Industrials | Fabricated Metal Products | United States | Nasdaq | |
| 1987 | $67.6M | Energy | Oil & Gas | United States | Nasdaq | |
| 1988 | $67.5M | Communication Services | Entertainment | United States | Nasdaq | |
| 1989 | $66.5M | Technology | Information Technology Services | United States | Nasdaq | |
| 1990 | $66.3M | Healthcare | Biotechnology | United States | Nasdaq | |
| 1991 | $66.3M | Technology | Electronic Components | United States | Nasdaq | |
| 1992 | $66.2M | Consumer Cyclical | Miscellaneous Manufacturing | United States | Nasdaq | |
| 1993 | $66.0M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 1994 | $65.0M | Healthcare | Biotechnology | United States | Nasdaq | |
| 1995 | $64.8M | Consumer Cyclical | Restaurants | United States | Nasdaq | |
| 1996 | $64.6M | Technology | Electronic Components | United States | Nasdaq | |
| 1997 | $64.5M | Healthcare | Biotechnology | United States | Nasdaq | |
| 1998 | $64.3M | Consumer Defensive | Tobacco | United States | Nasdaq | |
| 1999 | $64.2M | Industrials | Wholesale Distribution | United States | Nasdaq | |
| 2000 | $64.0M | Real Estate | REIT | United States | Nasdaq |