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    Largest companies by net assets

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    Companies ranked by net assets, in USD
    CompanyNet assetsSectorIndustryCountryExchange
    1PFEPFIZER INC$85.19BHealthcarePharmaceuticalsUnited StatesNYSE
    2JNJJOHNSON & JOHNSON$84.97BHealthcarePharmaceuticalsUnited StatesNYSE
    3ABTABBOTT LABORATORIES$51.11BHealthcarePharmaceuticalsUnited StatesNYSE
    4MRKMerck & Co., Inc.$41.93BHealthcarePharmaceuticalsUnited StatesNYSE
    5LLYELI LILLY & Co$33.88BHealthcarePharmaceuticalsUnited StatesNYSE
    6REGNREGENERON PHARMACEUTICALS, INC.$31.71BHealthcarePharmaceuticalsUnited StatesNasdaq
    7VRTXVERTEX PHARMACEUTICALS INC / MA$20.25BHealthcarePharmaceuticalsUnited StatesNasdaq
    8VTRSViatris Inc$14.26BHealthcarePharmaceuticalsUnited StatesNasdaq
    9RPRXRoyalty Pharma plc$9.79BHealthcarePharmaceuticalsUnited StatesNasdaq
    10ELANElanco Animal Health Inc$6.59BHealthcarePharmaceuticalsUnited StatesNYSE
    11UTHRUNITED THERAPEUTICS Corp$6.40BHealthcarePharmaceuticalsUnited StatesNasdaq
    12BMRNBIOMARIN PHARMACEUTICAL INC$6.32BHealthcarePharmaceuticalsUnited StatesNasdaq
    13ONCBeOne Medicines Ltd.$5.17BHealthcarePharmaceuticalsUnited StatesNasdaq
    14JAZZJazz Pharmaceuticals plc$4.80BHealthcarePharmaceuticalsUnited StatesNasdaq
    15ROIVRoivant Sciences Ltd.$4.23BHealthcarePharmaceuticalsUnited StatesNasdaq
    16ZTSZoetis Inc.$3.15BHealthcarePharmaceuticalsUnited StatesNYSE
    17PRGOPERRIGO Co plc$2.52BHealthcarePharmaceuticalsUnited StatesNYSE
    18PBHPrestige Consumer Healthcare Inc.$1.92BHealthcarePharmaceuticalsUnited StatesNYSE
    19ALKSAlkermes plc.$1.81BHealthcarePharmaceuticalsUnited StatesNasdaq
    20GPCRStructure Therapeutics Inc.$1.35BHealthcarePharmaceuticalsUnited StatesNasdaq
    21ALNYALNYLAM PHARMACEUTICALS, INC.$1.35BHealthcarePharmaceuticalsUnited StatesNasdaq
    22PRAXPraxis Precision Medicines, Inc.$1.34BHealthcarePharmaceuticalsUnited StatesNasdaq
    23XENEXenon Pharmaceuticals Inc.$1.24BHealthcarePharmaceuticalsUnited StatesNasdaq
    24INVAInnoviva, Inc.$1.23BHealthcarePharmaceuticalsUnited StatesNasdaq
    25OPKOPKO HEALTH, INC.$1.18BHealthcarePharmaceuticalsUnited StatesNasdaq
    26DNTHDianthus Therapeutics, Inc. /DE/$1.17BHealthcarePharmaceuticalsUnited StatesNasdaq
    27KLRAKailera Therapeutics, Inc.$1.12BHealthcarePharmaceuticalsUnited StatesNasdaq
    28ORKAOruka Therapeutics, Inc.$1.11BHealthcarePharmaceuticalsUnited StatesNasdaq
    29SYRESpyre Therapeutics, Inc.$1.10BHealthcarePharmaceuticalsUnited StatesNasdaq
    30PBLSParabilis Medicines, Inc.$1.05BHealthcarePharmaceuticalsUnited StatesNasdaq
    31SUPNSUPERNUS PHARMACEUTICALS, INC.$1.03BHealthcarePharmaceuticalsUnited StatesNasdaq
    32AGIOAGIOS PHARMACEUTICALS, INC.$1.03BHealthcarePharmaceuticalsUnited StatesNasdaq
    33TNGXTango Therapeutics, Inc.$1.02BHealthcarePharmaceuticalsUnited StatesNasdaq
    34OGNOrganon & Co.$1.01BHealthcarePharmaceuticalsUnited StatesNYSE
    35HRMYHarmony Biosciences Holdings, Inc.$999.24MHealthcarePharmaceuticalsUnited StatesNasdaq
    36LGNDLIGAND PHARMACEUTICALS INC$967.52MHealthcarePharmaceuticalsUnited StatesNasdaq
    37JANXJanux Therapeutics, Inc.$927.98MHealthcarePharmaceuticalsUnited StatesNasdaq
    38NKTRNEKTAR THERAPEUTICS$903.12MHealthcarePharmaceuticalsUnited StatesNasdaq
    39ABCLAbCellera Biologics Inc.$896.02MHealthcarePharmaceuticalsUnited StatesNasdaq
    40ELVNEnliven Therapeutics, Inc.$895.15MHealthcarePharmaceuticalsUnited StatesNasdaq
    41PTGXProtagonist Therapeutics, Inc$841.54MHealthcarePharmaceuticalsUnited StatesNasdaq
    42MANEVeradermics, Inc$813.61MHealthcarePharmaceuticalsUnited StatesNYSE
    43INSMINSMED Inc$757.49MHealthcarePharmaceuticalsUnited StatesNasdaq
    44CORTCORCEPT THERAPEUTICS INC$705.78MHealthcarePharmaceuticalsUnited StatesNasdaq
    45DYNDyne Therapeutics, Inc.$702.15MHealthcarePharmaceuticalsUnited StatesNasdaq
    46PCRXPacira BioSciences, Inc.$671.98MHealthcarePharmaceuticalsUnited StatesNasdaq
    47VRDNViridian Therapeutics, Inc.\DE$662.10MHealthcarePharmaceuticalsUnited StatesNasdaq
    48KNSAKiniksa Pharmaceuticals International, plc$654.15MHealthcarePharmaceuticalsUnited StatesNasdaq
    49IRONDisc Medicine, Inc.$644.16MHealthcarePharmaceuticalsUnited StatesNasdaq
    50NAMSNewAmsterdam Pharma Co N.V.$631.42MHealthcarePharmaceuticalsUnited StatesNasdaq
    51SMMTSummit Therapeutics Inc.$629.98MHealthcarePharmaceuticalsUnited StatesNasdaq
    52KARDKardigan, Inc.$615.52MHealthcarePharmaceuticalsUnited StatesNasdaq
    53TGTXTG THERAPEUTICS, INC.$604.08MHealthcarePharmaceuticalsUnited StatesNasdaq
    54ANIPANI PHARMACEUTICALS INC$597.21MHealthcarePharmaceuticalsUnited StatesNasdaq
    55MLYSMineralys Therapeutics, Inc.$550.92MHealthcarePharmaceuticalsUnited StatesNasdaq
    56COGTCogent Biosciences, Inc.$532.39MHealthcarePharmaceuticalsUnited StatesNasdaq
    57IMNMImmunome Inc.$525.08MHealthcarePharmaceuticalsUnited StatesNasdaq
    58MDGLMADRIGAL PHARMACEUTICALS, INC.$523.72MHealthcarePharmaceuticalsUnited StatesNasdaq
    59OCULOCULAR THERAPEUTIX, INC$520.04MHealthcarePharmaceuticalsUnited StatesNasdaq
    60XNCRXencor Inc$503.23MHealthcarePharmaceuticalsUnited StatesNasdaq
    61AKTSAktis Oncology, Inc.$484.84MHealthcarePharmaceuticalsUnited StatesNasdaq
    62ALTAltimmune, Inc.$474.21MHealthcarePharmaceuticalsUnited StatesNasdaq
    63BCAXBicara Therapeutics Inc.$468.77MHealthcarePharmaceuticalsUnited StatesNasdaq
    64ARWRARROWHEAD PHARMACEUTICALS, INC.$465.53MHealthcarePharmaceuticalsUnited StatesNasdaq
    65CRMDCorMedix Inc.$460.83MHealthcarePharmaceuticalsUnited StatesNasdaq
    66WVEWave Life Sciences, Inc.$453.52MHealthcarePharmaceuticalsUnited StatesNasdaq
    67ALMSALUMIS INC.$452.16MHealthcarePharmaceuticalsUnited StatesNasdaq
    68AVTXAvalo Therapeutics, Inc.$448.66MHealthcarePharmaceuticalsUnited StatesNasdaq
    69EWTXEdgewise Therapeutics, Inc.$448.08MHealthcarePharmaceuticalsUnited StatesNasdaq
    70IONSIONIS PHARMACEUTICALS INC$439.74MHealthcarePharmaceuticalsUnited StatesNasdaq
    71RAPPRapport Therapeutics, Inc.$422.93MHealthcarePharmaceuticalsUnited StatesNasdaq
    72SPTXSeaport Therapeutics, Inc.$422.60MHealthcarePharmaceuticalsUnited StatesNasdaq
    73MBXMBX Biosciences, Inc.$409.54MHealthcarePharmaceuticalsUnited StatesNasdaq
    74NRIXNurix Therapeutics, Inc.$402.63MHealthcarePharmaceuticalsUnited StatesNasdaq
    75AVLNAvalyn Pharma Inc.$398.35MHealthcarePharmaceuticalsUnited StatesNasdaq
    76PAHCPHIBRO ANIMAL HEALTH CORP$385.48MHealthcarePharmaceuticalsUnited StatesNasdaq
    77ORICOric Pharmaceuticals, Inc.$381.26MHealthcarePharmaceuticalsUnited StatesNasdaq
    78AVBPArriVent BioPharma, Inc.$366.84MHealthcarePharmaceuticalsUnited StatesNasdaq
    79ERASErasca, Inc.$361.87MHealthcarePharmaceuticalsUnited StatesNasdaq
    80TYRATyra Biosciences, Inc.$353.66MHealthcarePharmaceuticalsUnited StatesNasdaq
    81MPLTMapLight Therapeutics, Inc.$348.30MHealthcarePharmaceuticalsUnited StatesNasdaq
    82STOKStoke Therapeutics, Inc.$345.55MHealthcarePharmaceuticalsUnited StatesNasdaq
    83EBSEmergent BioSolutions Inc.$341.40MHealthcarePharmaceuticalsUnited StatesNYSE
    84LBRXLB PHARMACEUTICALS INC$332.35MHealthcarePharmaceuticalsUnited StatesNasdaq
    85QUREuniQure N.V.$324.05MHealthcarePharmaceuticalsUnited StatesNasdaq
    86BBOTBridgeBio Oncology Therapeutics, Inc.$323.11MHealthcarePharmaceuticalsUnited StatesNasdaq
    87TRVITrevi Therapeutics, Inc.$321.51MHealthcarePharmaceuticalsUnited StatesNasdaq
    88COLLCOLLEGIUM PHARMACEUTICAL, INC$311.91MHealthcarePharmaceuticalsUnited StatesNasdaq
    89FULCFulcrum Therapeutics, Inc.$310.70MHealthcarePharmaceuticalsUnited StatesNasdaq
    90ASMBASSEMBLY BIOSCIENCES, INC.$305.65MHealthcarePharmaceuticalsUnited StatesNasdaq
    91PRTAPROTHENA CORP PUBLIC LTD CO$286.89MHealthcarePharmaceuticalsUnited StatesNasdaq
    92UPBUpstream Bio, Inc.$270.96MHealthcarePharmaceuticalsUnited StatesNasdaq
    93SIONSionna Therapeutics, Inc.$265.77MHealthcarePharmaceuticalsUnited StatesNasdaq
    94KROSKeros Therapeutics, Inc.$262.32MHealthcarePharmaceuticalsUnited StatesNasdaq
    95ABUSArbutus Biopharma Corp$258.73MHealthcarePharmaceuticalsUnited StatesNasdaq
    96NUVBNuvation Bio Inc.$253.86MHealthcarePharmaceuticalsUnited StatesNYSE
    97NKTXNkarta, Inc.$247.74MHealthcarePharmaceuticalsUnited StatesNasdaq
    98ZBIOZenas BioPharma, Inc.$247.10MHealthcarePharmaceuticalsUnited StatesNasdaq
    99CAPRCAPRICOR THERAPEUTICS, INC.$246.22MHealthcarePharmaceuticalsUnited StatesNasdaq
    100CTNMContineum Therapeutics, Inc.$239.66MHealthcarePharmaceuticalsUnited StatesNasdaq

    U.S.-exchange common stocks; ADRs and funds excluded. 334 companies. Reported USD values. TTM means trailing twelve months; companies without a comparable value are excluded.