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    TYRA

    Tyra Biosciences, Inc.

    Company overview

    Market capitalization
    $1.28B
    Employees
    87
    Latest publication
    2026-09-29
    About Tyra Biosciences, Inc.

    Tyra Biosciences, Inc., a clinical-stage biotechnology company, develops precision medicines for fibroblast growth factor receptor (FGFR) biology in the United States. The company offers SNÅP, a precision medicine platform that enables drug design through iterative molecular snapshots to predict genetic alterations for developing therapies targeting oncology and genetically defined conditions. Its lead product candidate is FGFR3, which is in clinical trials for the treatment of patients with metastatic urothelial carcinoma and other solid tumors. The company is also developing TYRA-300 for skeletal conditions, including achondroplasia, hypochondroplasia, dysplasia, and other FGFR3-driven genetic syndromes; TYRA-200, a candidate in clinical trial for intrahepatic cholangiocarcinoma; and TYRA-430 for the treatment of hepatocellular carcinoma. Tyra Biosciences, Inc. was incorporated in 2018 and is headquartered in Carlsbad, California.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Total Revenue0USD0USD0USD0USD0USD496,000USD0USD0USD
    Cost Of Revenue138,000USD132,000USD—140,000USD143,000USD—127,000USD126,000USD
    Gross Profit-138,000USD-132,000USD—-140,000USD-143,000USD248,000USD-127,000USD-126,000USD
    Research Development33,332,000USD28,186,000USD25,469,000USD24,309,000USD24,964,000USD22,180,000USD22,697,000USD17,871,000USD
    Selling General Administrative8,528,000USD8,330,000USD7,475,000USD7,143,000USD6,886,000USD7,564,000USD5,907,000USD5,535,000USD
    Total Operating Expenses41,860,000USD36,516,000USD32,944,000USD31,452,000USD31,850,000USD29,744,000USD28,604,000USD23,406,000USD
    Operating Income-41,998,000USD-36,516,000USD-32,944,000USD-31,452,000USD-31,850,000USD-29,744,000USD-28,604,000USD-23,532,000USD
    Interest Income2,693,000USD2,682,000USD3,076,000USD3,354,000USD3,703,000USD4,173,000USD4,588,000USD4,830,000USD
    Net Interest Income2,693,000USD2,682,000USD3,076,000USD3,354,000USD3,703,000USD4,173,000USD4,588,000USD4,830,000USD
    Income Before Tax-39,305,000USD-33,834,000USD-29,868,000USD-28,098,000USD-28,147,000USD-25,571,000USD-24,016,000USD-18,702,000USD
    Net Income-39,305,000USD-33,834,000USD-29,868,000USD-28,098,000USD-28,147,000USD-25,571,000USD-24,016,000USD-18,702,000USD
    Net Income From Continuing Ops-39,305,000USD-33,834,000USD-29,868,000USD-28,098,000USD-28,147,000USD-25,571,000USD-24,016,000USD-18,702,000USD
    Ebit-41,998,000USD-36,516,000USD-29,868,000USD-31,452,000USD-31,850,000USD-29,744,000USD-28,604,000USD-23,532,000USD
    Ebitda-41,860,000USD-36,384,000USD-29,737,000USD-31,312,000USD-31,707,000USD-29,600,000USD-28,477,000USD-23,406,000USD
    Depreciation And Amortization138,000USD132,000USD131,000USD140,000USD143,000USD144,000USD127,000USD126,000USD
    Reconciled Depreciation138,000USD132,000USD131,000USD140,000USD143,000USD144,000USD127,000USD126,000USD
    Total Other Income Expense Net2,693,000USD2,682,000USD3,076,000USD3,354,000USD3,703,000USD4,173,000USD4,588,000USD4,830,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USD
    Total Revenue0USD0USD0USD0USD0USD0USD0USD
    Cost Of Revenue546,000USD519,000USD353,000USD296,000USD140,000USD47,000USD8,000USD
    Gross Profit-546,000USD-519,000USD-353,000USD-296,000USD-140,000USD-47,000USD-8,000USD
    Research Development102,928,000USD80,077,000USD62,518,000USD43,008,000USD20,636,000USD7,203,000USD1,790,000USD
    Selling General Administrative29,834,000USD24,100,000USD17,427,000USD15,919,000USD5,652,000USD2,094,000USD1,332,000USD
    Total Operating Expenses132,762,000USD104,177,000USD79,945,000USD58,927,000USD26,288,000USD9,250,000USD3,122,000USD
    Operating Income-132,762,000USD-104,177,000USD-79,945,000USD-58,927,000USD-26,288,000USD-9,297,000USD-3,122,000USD
    Interest Income12,815,000USD17,696,000USD10,850,000USD3,652,000USD13,000USD——
    Net Interest Income12,815,000USD17,696,000USD10,850,000USD3,652,000USD13,000USD-1,000USD-1,000USD
    Income Before Tax-119,947,000USD-86,481,000USD-69,134,000USD-55,325,000USD-26,294,000USD-9,336,000USD-4,065,000USD
    Net Income-119,947,000USD-86,481,000USD-69,134,000USD-51,723,000USD-26,141,000USD-9,314,000USD-4,058,000USD
    Net Income From Continuing Ops-119,947,000USD-86,481,000USD-69,134,000USD-55,325,000USD-26,294,000USD-9,336,000USD-4,065,000USD
    Ebit-132,762,000USD-104,177,000USD-79,945,000USD-58,927,000USD-26,288,000USD-9,297,000USD-3,122,000USD
    Ebitda-132,216,000USD-103,658,000USD-79,588,000USD-58,631,000USD-26,148,000USD-9,250,000USD-3,114,000USD
    Depreciation And Amortization546,000USD519,000USD357,000USD296,000USD140,000USD47,000USD8,000USD
    Reconciled Depreciation546,000USD519,000USD353,000USD296,000USD140,000USD47,000USD8,000USD
    Total Other Income Expense Net12,815,000USD17,696,000USD10,811,000USD3,602,000USD-6,000USD-39,000USD-943,000USD
    Interest Expense———296,000USD140,000USD1,000USD1,000USD
    Income Tax Expense———-3,602,000USD-153,000USD-22,000USD-7,000USD
    Non Operating Income Net Other———3,602,000USD-6,000USD——
    Net Income Applicable To Common Shares———-55,325,000USD-26,294,000USD-9,336,000USD-4,065,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets383,362,000USD412,040,000USD282,609,000USD301,851,000USD321,499,000USD343,476,000USD363,558,000USD380,592,000USD
    Cash And Equivalents73,835,000USD———————
    Total Current Assets366,966,000USD394,613,000USD265,450,000USD281,216,000USD302,155,000USD324,566,000USD347,463,000USD365,611,000USD
    Other Current Assets13,022,000USD11,147,000USD9,447,000USD4,092,000USD4,184,000USD3,823,000USD4,022,000USD3,581,000USD
    Other Non Current Assets9,028,000USD———————
    Total Liabilities29,698,000USD———————
    Total Current Liabilities24,620,000USD19,256,000USD18,094,000USD15,879,000USD13,770,000USD14,246,000USD14,594,000USD12,373,000USD
    Total Stockholder Equity353,664,000USD387,575,000USD259,177,000USD280,509,000USD302,147,000USD323,534,000USD343,151,000USD362,288,000USD
    Total Equity Including Noncontrolling Interest353,664,000USD———————
    Property Plant Equipment Net6,484,000USD6,658,000USD6,887,000USD7,045,000USD7,235,000USD7,468,000USD7,719,000USD7,975,000USD
    Accounts Payable2,334,000USD3,642,000USD1,178,000USD1,991,000USD2,245,000USD2,500,000USD590,000USD1,165,000USD
    Short Term Debt504,000USD488,000USD472,000USD456,000USD441,000USD426,000USD412,000USD398,000USD
    Common Stock6,000USD6,000USD5,000USD5,000USD5,000USD5,000USD5,000USD5,000USD
    Retained Earnings-456,121,000USD-410,563,000USD-371,258,000USD-337,424,000USD-307,556,000USD-279,458,000USD-251,311,000USD-225,740,000USD
    Accumulated Other Comprehensive Income-580,000USD107,000USD393,000USD442,000USD436,000USD688,000USD770,000USD1,752,000USD
    Total Liab—24,465,000USD23,432,000USD21,342,000USD19,352,000USD19,942,000USD20,407,000USD18,304,000USD
    Other Current Liab—15,126,000USD16,444,000USD13,432,000USD11,084,000USD11,320,000USD13,592,000USD10,810,000USD
    Capital Stock—6,000USD5,000USD5,000USD5,000USD5,000USD5,000USD5,000USD
    Cash—84,955,000USD77,387,000USD61,951,000USD98,490,000USD100,721,000USD91,966,000USD103,892,000USD
    Cash And Short Term Investments—383,466,000USD256,003,000USD274,924,000USD296,271,000USD318,943,000USD341,441,000USD360,130,000USD
    Net Debt—-79,258,000USD-71,577,000USD-56,032,000USD-92,467,000USD-94,599,000USD-85,744,000USD-97,574,000USD
    Short Long Term Debt Total—5,697,000USD5,810,000USD5,919,000USD6,023,000USD6,122,000USD6,222,000USD6,318,000USD
    Short Term Investments—298,511,000USD178,616,000USD212,973,000USD197,781,000USD218,222,000USD249,475,000USD256,238,000USD
    Property Plant Equipment Gross—6,658,000USD6,887,000USD7,045,000USD7,235,000USD8,861,000USD9,000,000USD9,154,000USD
    Common Stock Shares Outstanding—61,746,050shares59,602,328shares59,670,757shares59,550,771shares59,336,550shares58,874,497shares58,874,497shares
    Non Current Assets Total—17,427,000USD17,159,000USD20,634,999USD19,344,000USD18,910,000USD16,095,000USD14,981,000USD
    Non Current Liabilities Total—5,209,000USD5,338,000USD5,462,999USD5,582,000USD5,696,000USD5,813,000USD5,931,000USD
    Non Currrent Assets Other—10,769,000USD10,272,000USD12,589,999USD12,109,000USD11,442,000USD8,376,000USD6,006,000USD
    Net Working Capital—375,357,000USD247,356,000USD265,337,000USD288,385,000USD310,320,000USD332,869,000USD353,238,000USD
    Unclassified Non Current Liabilities—5,209,000USD5,338,000USD5,462,999USD5,582,000USD5,696,000USD5,810,000USD5,920,000USD
    Unclassified Equity—798,019,000USD630,032,000USD617,481,000USD609,257,000USD602,294,000USD593,682,000USD586,266,000USD
    Net Receivables———2,200,000USD1,700,000USD1,800,000USD2,000,000USD1,900,000USD
    Other Assets——————-1,539,000USD—
    Non Current Liabilities Other——————3,000USD11,000USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USD
    Total Assets282,609,000USD363,558,000USD225,857,000USD266,181,000USD306,701,000USD16,011,000USD528,000USD
    Other Current Assets9,447,000USD4,022,000USD8,202,000USD6,075,000USD1,875,000USD57,000USD19,000USD
    Total Liab23,432,000USD20,407,000USD21,595,000USD8,352,000USD4,964,000USD29,649,000USD5,269,000USD
    Total Stockholder Equity259,177,000USD343,151,000USD204,262,000USD257,829,000USD301,737,000USD-13,638,000USD-4,741,000USD
    Other Current Liab16,444,000USD13,592,000USD10,391,000USD4,416,000USD2,815,000USD1,052,000USD4,689,000USD
    Common Stock5,000USD5,000USD4,000USD4,000USD4,000USD——
    Capital Stock5,000USD5,000USD4,000USD4,000USD4,000USD0USD0USD
    Retained Earnings-371,258,000USD-251,311,000USD-164,830,000USD-95,696,000USD-40,371,000USD-14,077,000USD-4,741,000USD
    Cash77,387,000USD91,966,000USD58,006,000USD251,213,000USD302,182,000USD15,224,000USD108,000USD
    Cash And Short Term Investments256,003,000USD341,441,000USD203,469,000USD251,213,000USD302,182,000USD15,224,000USD108,000USD
    Total Current Assets265,450,000USD347,463,000USD211,671,000USD257,288,000USD304,057,000USD15,281,000USD127,000USD
    Total Current Liabilities18,094,000USD14,594,000USD15,333,000USD5,701,000USD3,616,000USD1,858,000USD5,155,000USD
    Net Debt-71,577,000USD-85,744,000USD-51,510,000USD-248,591,000USD-300,999,000USD-15,082,000USD145,000USD
    Short Term Debt472,000USD412,000USD280,000USD140,000USD202,000USD142,000USD139,000USD
    Short Long Term Debt Total5,810,000USD6,222,000USD6,496,000USD2,622,000USD1,183,000USD142,000USD253,000USD
    Short Term Investments178,616,000USD249,475,000USD145,463,000USD0USD———
    Accounts Payable1,178,000USD590,000USD4,662,000USD1,145,000USD599,000USD664,000USD327,000USD
    Property Plant Equipment Net6,887,000USD7,719,000USD8,154,000USD3,543,000USD2,089,000USD466,000USD276,000USD
    Property Plant Equipment Gross6,887,000USD9,000,000USD8,961,000USD4,004,000USD2,089,000USD509,000USD281,000USD
    Accumulated Other Comprehensive Income393,000USD770,000USD381,000USD0USD-306,701,000USD——
    Common Stock Shares Outstanding59,602,328shares57,217,746shares42,704,876shares41,883,904shares41,441,135shares42,535,139shares42,535,139shares
    Non Current Assets Total17,159,000USD16,095,000USD14,186,000USD8,893,000USD2,644,000USD730,000USD401,000USD
    Non Current Liabilities Total5,338,000USD5,813,000USD6,262,000USD2,651,000USD1,348,000USD27,791,000USD114,000USD
    Non Currrent Assets Other10,272,000USD8,376,000USD6,032,000USD5,350,000USD555,000USD21,000USD125,000USD
    Net Working Capital247,356,000USD332,869,000USD196,338,000USD251,587,000USD300,441,000USD13,423,000USD-5,028,000USD
    Unclassified Non Current Liabilities5,338,000USD5,810,000USD6,216,000USD——27,511,000USD—
    Unclassified Equity630,032,000USD593,682,000USD368,703,000USD353,517,000USD648,801,000USD——
    Net Receivables—2,000,000USD700,000USD————
    Non Current Liabilities Other—3,000USD46,000USD2,651,000USD1,348,000USD140,000USD—
    Other Liab———169,000USD367,000USD140,000USD—
    Other Assets———5,350,000USD555,000USD0USD125,000USD
    Net Tangible Assets———257,829,000USD301,737,000USD-13,638,000USD-4,741,000USD
    Unclassified Non Current Assets———-5,350,000USD———
    Deferred Long Term Liab——————107,000USD
    Current Deferred Revenue——————364,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-39,305,000USD-33,834,000USD-29,868,000USD-28,098,000USD-28,147,000USD-25,571,000USD-24,016,000USD-18,702,000USD
    Depreciation138,000USD132,000USD131,000USD140,000USD143,000USD144,000USD127,000USD126,000USD
    Stock Based Compensation7,847,000USD7,627,000USD7,577,000USD6,380,000USD6,422,000USD6,702,000USD7,573,000USD4,411,000USD
    Other Non Cash Items-65,000USD-126,000USD-419,000USD-708,000USD-866,000USD-1,183,000USD-1,605,000USD-1,867,000USD
    Change In Working Capital-1,186,000USD2,577,000USD199,000USD-1,394,000USD-3,010,000USD318,000USD23,000USD5,774,000USD
    Total Cash From Operating Activities-32,571,000USD-23,624,000USD-22,380,000USD-23,680,000USD-25,458,000USD-19,590,000USD-17,898,000USD-10,258,000USD
    Capital Expenditures-88,000USD-57,000USD-39,000USD-31,000USD-14,000USD-6,000USD-52,000USD-470,000USD
    Free Cash Flow-32,659,000USD-23,681,000USD-22,419,000USD-23,711,000USD-25,472,000USD-19,596,000USD-17,950,000USD-10,728,000USD
    Investments-120,156,000USD34,434,000USD-14,806,000USD20,866,000USD32,026,000USD6,958,000USD21,557,000USD-144,991,000USD
    Total Cashflows From Investing Activities-120,244,000USD34,377,000USD-14,806,000USD20,866,000USD32,026,000USD6,958,000USD21,557,000USD-144,991,000USD
    Total Cash From Financing Activities160,383,000USD4,683,000USD647,000USD583,000USD2,187,000USD706,000USD743,000USD373,000USD
    Issuance Of Capital Stock147,853,000USD0USD0USD0USD0USD0USD0USD0USD
    Change In Cash7,568,000USD15,436,000USD-36,539,000USD-2,231,000USD8,755,000USD-11,926,000USD4,402,000USD-154,876,000USD
    Begin Period Cash Flow78,387,000USD62,951,000USD98,490,000USD101,721,000USD92,966,000USD104,892,000USD99,490,000USD255,366,000USD
    End Period Cash Flow85,955,000USD78,387,000USD61,951,000USD99,490,000USD101,721,000USD92,966,000USD103,892,000USD100,490,000USD
    Other Cashflows From Financing Activities160,383,000USD4,683,000USD647,000USD—2,187,000USD706,000USD743,000USD624,000USD
    Unclassified Financing Cash Flow-147,853,000USD———————
    Sale Purchase Of Stock—0USD0USD0USD0USD0USD420,000USD-251,000USD
    Other Cashflows From Investing Activities——————-1USD-144,521USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USD
    Net Income-119,947,000USD-86,481,000USD-69,134,000USD-55,325,000USD-26,294,000USD-9,336,000USD-4,065,000USD
    Depreciation546,000USD519,000USD353,000USD296,000USD140,000USD47,000USD8,000USD
    Stock Based Compensation28,006,000USD22,801,000USD13,525,000USD10,588,000USD2,887,000USD439,000USD0USD
    Other Non Cash Items-2,119,000USD-5,884,000USD12,282,000USD3,000USD3,000USD17,000USD934,000USD
    Change In Working Capital-1,628,000USD-729,000USD6,360,000USD-5,847,000USD-481,000USD1,070,000USD505,000USD
    Total Cash From Operating Activities-95,142,000USD-69,774,000USD-50,139,000USD-50,285,000USD-23,745,000USD-7,763,000USD-2,618,000USD
    Capital Expenditures-141,000USD-664,000USD-770,000USD-559,000USD-661,000USD-312,000USD-20,000USD
    Free Cash Flow-95,283,000USD-70,438,000USD-50,909,000USD-50,844,000USD-24,406,000USD-8,075,000USD-2,638,000USD
    Investments72,604,000USD-98,403,000USD-144,605,000USD-559,000USD-645,000USD-312,000USD-20,000USD
    Total Cashflows From Investing Activities72,463,000USD-98,403,000USD-144,605,000USD-559,000USD-645,000USD-312,000USD-20,000USD
    Total Cash From Financing Activities8,100,000USD202,137,000USD1,537,000USD632,000USD311,348,000USD23,434,000USD157,000USD
    Sale Purchase Of Stock0USD-420,000USD0USD—311,382,000USD——
    Issuance Of Capital Stock0USD200,000,000USD0USD181,336,000USD310,843,000USD23,311,000USD0USD
    Change In Cash-14,579,000USD33,960,000USD-193,207,000USD-50,969,000USD286,958,000USD15,359,000USD-2,481,000USD
    Begin Period Cash Flow92,966,000USD59,006,000USD251,213,000USD302,182,000USD15,467,000USD108,000USD2,589,000USD
    End Period Cash Flow78,387,000USD92,966,000USD58,006,000USD251,213,000USD302,425,000USD15,467,000USD108,000USD
    Other Cashflows From Financing Activities8,100,000USD2,557,000USD1,537,000USD632,000USD130,137,000USD23,451,000USD165,000USD
    Unclassified Financing Cash Flow—200,000,000USD—-181,336,000USD-130,146,000USD-23,311,000USD—
    Unclassified Operating Cash Flow——-13,525,000USD————
    Change To Liabilities———2,357,000USD1,492,000USD1,019,000USD461,000USD
    Net Borrowings———0USD-25,000USD-17,000USD-8,000USD
    Cash And Cash Equivalents Changes———-50,212,000USD286,958,000USD——
    Other Cashflows From Investing Activities————16USD——
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    No revenue breakdown is currently published for this company.

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.