| Rank | Company | Operating income | Sector | Industry | Country | Exchange |
|---|---|---|---|---|---|---|
| 1 | $16.9B | Healthcare | Pharmaceuticals | United States | NYSE | |
| 2 | $11.4B | Healthcare | Biotechnology | United States | Nasdaq | |
| 3 | $8.29B | Healthcare | Pharmaceutical Retailers | United States | NYSE | |
| 4 | $8.15B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 5 | $7.35B | Healthcare | Pharmaceuticals | United States | NYSE | |
| 6 | $6.79B | Healthcare | Medical Devices | United States | NYSE | |
| 7 | $5.53B | Healthcare | Medical Devices | United States | NYSE | |
| 8 | $5.13B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 9 | $4.78B | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 10 | $4.62B | Healthcare | Medical Devices | United States | NYSE | |
| 11 | $4.60B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 12 | $4.54B | Healthcare | Healthcare Providers | United States | NYSE | |
| 13 | $4.15B | Healthcare | Medical Devices | United States | NYSE | |
| 14 | $4.04B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 15 | $3.98B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 16 | $3.84B | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 17 | $3.45B | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 18 | $2.73B | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 19 | $2.48B | Healthcare | Medical Devices | United States | NYSE | |
| 20 | $2.32B | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 21 | $2.20B | Healthcare | Diagnostics & Research | United States | NYSE | |
| 22 | $2.13B | Healthcare | Healthcare Providers | United States | NYSE | |
| 23 | $2.12B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 24 | $2.08B | Healthcare | Medical Devices | United States | NYSE | |
| 25 | $2.06B | Healthcare | Healthcare Providers | United States | NYSE | |
| 26 | $2.04B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 27 | $1.89B | Healthcare | Medical Devices | United States | NYSE | |
| 28 | $1.78B | Healthcare | Diagnostics & Research | United States | Nasdaq | |
| 29 | $1.64B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 30 | $1.63B | Healthcare | Healthcare Providers | United States | NYSE | |
| 31 | $1.51B | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 32 | $1.50B | Healthcare | Healthcare Providers | United States | NYSE | |
| 33 | $1.46B | Healthcare | Diagnostics & Research | United States | Nasdaq | |
| 34 | $1.45B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 35 | $1.40B | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 36 | $1.36B | Healthcare | Healthcare Providers | United States | NYSE | |
| 37 | $1.35B | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 38 | $1.33B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 39 | $1.29B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 40 | $1.24B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 41 | $1.21B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 42 | $1.14B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 43 | $1.14B | Healthcare | Medical Devices | United States | Nasdaq | |
| 44 | $1000M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 45 | $972M | Healthcare | Biotechnology | United States | Nasdaq | |
| 46 | $897M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 47 | $883M | Healthcare | Pharmaceuticals | United States | NYSE | |
| 48 | $882M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 49 | $795M | Healthcare | Biotechnology | United States | Nasdaq | |
| 50 | $787M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 51 | $681M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 52 | $680M | Healthcare | Medical Devices | United States | NYSE | |
| 53 | $643M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 54 | $640M | Healthcare | Medical Devices | United States | NYSE | |
| 55 | $622M | Healthcare | Healthcare Providers | United States | Nasdaq | |
| 56 | $597M | Healthcare | Biotechnology | United States | Nasdaq | |
| 57 | $583M | Healthcare | Diagnostics & Research | United States | Nasdaq | |
| 58 | $577M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 59 | $548M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 60 | $544M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 61 | $516M | Healthcare | Medical Devices | United States | Nasdaq | |
| 62 | $467M | Healthcare | Healthcare Providers | United States | Nasdaq | |
| 63 | $454M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 64 | $448M | Healthcare | Healthcare Providers | United States | Nasdaq | |
| 65 | $421M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 66 | $413M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 67 | $410M | Healthcare | Healthcare Providers | United States | NYSE | |
| 68 | $398M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 69 | $384M | Healthcare | Healthcare Providers | United States | Nasdaq | |
| 70 | $375M | Healthcare | Healthcare Providers | United States | NYSE | |
| 71 | $359M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 72 | $349M | Healthcare | Healthcare Providers | United States | NYSE | |
| 73 | $334M | Healthcare | Healthcare Providers | United States | Nasdaq | |
| 74 | $330M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 75 | $323M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 76 | $311M | Healthcare | Health Services | United States | NYSE | |
| 77 | $304M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 78 | $302M | Healthcare | Diagnostics & Research | United States | Nasdaq | |
| 79 | $290M | Healthcare | Pharmaceuticals | United States | NYSE | |
| 80 | $284M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 81 | $274M | Healthcare | Healthcare Providers | United States | Nasdaq | |
| 82 | $274M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 83 | $252M | Healthcare | Biotechnology | United States | Nasdaq | |
| 84 | $238M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 85 | $234M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 86 | $231M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 87 | $224M | Healthcare | Biotechnology | United States | Nasdaq | |
| 88 | $224M | Healthcare | Medical Devices | United States | Nasdaq | |
| 89 | $217M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 90 | $215M | Healthcare | Healthcare Providers | United States | NYSE | |
| 91 | $201M | Healthcare | Medical Devices | United States | Nasdaq | |
| 92 | $198M | Healthcare | Biotechnology | United States | Nasdaq | |
| 93 | $194M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 94 | $188M | Healthcare | Medical Devices | United States | Nasdaq | |
| 95 | $187M | Healthcare | Medical Devices | United States | NYSE | |
| 96 | $184M | Healthcare | Biotechnology | United States | Nasdaq | |
| 97 | $179M | Healthcare | Medical Devices | United States | NYSE | |
| 98 | $169M | Healthcare | Pharmaceuticals | United States | Nasdaq | |
| 99 | $164M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 100 | $163M | Healthcare | Pharmaceuticals | United States | Nasdaq |