| Rank | Company | Operating income | Sector | Industry | Country | Exchange |
|---|---|---|---|---|---|---|
| 1 | $8.15B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 2 | $5.13B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 3 | $4.60B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 4 | $4.04B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 5 | $3.98B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 6 | $3.45B | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 7 | $2.73B | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 8 | $2.32B | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 9 | $2.12B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 10 | $2.04B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 11 | $1.64B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 12 | $1.45B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 13 | $1.35B | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 14 | $1.33B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 15 | $1.29B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 16 | $1.24B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 17 | $1.21B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 18 | $1.14B | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 19 | $882M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 20 | $787M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 21 | $681M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 22 | $643M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 23 | $577M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 24 | $548M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 25 | $544M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 26 | $413M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 27 | $398M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 28 | $359M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 29 | $330M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 30 | $323M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 31 | $304M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 32 | $284M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 33 | $274M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 34 | $238M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 35 | $164M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 36 | $135M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 37 | $83.9M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 38 | $82.8M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 39 | $69.1M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 40 | $54.5M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 41 | $53.1M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 42 | $48.5M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 43 | $47.4M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 44 | $32.0M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 45 | $22.5M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 46 | $13.7M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 47 | $11.6M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 48 | $8.42M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 49 | $5.74M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 50 | $5.27M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 51 | $4.64M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 52 | $1.83M | Healthcare | Medical Instruments & Supplies | United States | Nasdaq | |
| 53 | $1.55M | Healthcare | Medical Instruments & Supplies | United States | NYSE | |
| 54 | $0.65M | Healthcare | Medical Instruments & Supplies | United States | NYSE |