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    XBIO

    Xenetic Biosciences, Inc.

    Company overview

    Market capitalization
    $5.46M
    Employees
    2
    Latest publication
    2026-09-29
    About Xenetic Biosciences, Inc.

    Xenetic Biosciences, Inc., a biopharmaceutical company, focuses on advancing immune-oncology technologies to treat cancers. Its DNase technology targets neutrophil extracellular traps (NETS), which are involved in cancer growth, metastasis, and progression, and contribute to immunotherapy, chemotherapy, and radiotherapy resistance. The company's product pipeline includes XBIO-015 for the treatment of pancreatic carcinoma and solid tumors; XBIO-020 for the treatment of solid tumors; and ErepoXen, which uses PolyXen platform technology for the treatment of anemia in chronic kidney disease (CKD) patients. It has a sublicensing agreement with Takeda Pharmaceutical Co. Ltd, as well as various research, development, license and supply agreements with Serum Institute of India, PJSC Pharmsynthez, and SynBio, LLC. Xenetic Biosciences, Inc. is headquartered in Framingham, Massachusetts.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Revenue660,601USD806,923USD766,296USD1,026,956USD589,897USD593,261USD648,820USD614,243USD
    Research Development552,013USD661,443USD773,416USD756,482USD656,557USD879,029USD1,042,255USD367,985USD
    General And Administrative Expenses1,080,278USD———————
    Total Operating Expenses1,632,291USD1,309,040USD1,389,323USD1,571,690USD1,314,309USD1,535,670USD1,747,965USD1,113,716USD
    Operating Income-971,690USD-502,117USD-623,027USD-544,734USD-724,412USD-942,409USD-1,099,145USD-499,473USD
    Total Other Income Expense Net41,995USD45,735USD43,951USD34,795USD35,709USD39,268USD44,624USD62,802USD
    Interest Income42,067USD45,756USD43,792USD30,783USD34,232USD39,190USD51,867USD61,298USD
    Net Income-929,695USD-456,382USD-579,076USD-509,939USD-688,703USD-903,141USD-1,054,521USD-436,671USD
    Gross Profit—806,923USD766,296USD1,026,956USD589,897USD593,261USD648,820USD614,243USD
    Selling General Administrative—647,597USD615,907USD815,209USD657,752USD656,641USD705,710USD745,731USD
    Net Interest Income—45,756USD43,792USD30,783USD34,232USD39,190USD51,867USD61,298USD
    Income Before Tax—-456,382USD-579,076USD-509,939USD-688,703USD-903,141USD-1,054,521USD-436,671USD
    Net Income From Continuing Ops—-456,382USD-579,076USD-509,940USD-688,703USD-903,141USD-1,054,521USD-436,671USD
    Ebitda—-502,117USD-623,027USD-523,176USD-724,412USD-942,409USD-1,099,145USD-499,473USD
    Ebit———-509,939USD—-1,109,769USD——
    Depreciation And Amortization———-13,237USD—10,624USD——
    Income Tax Expense—————-10,624USD—-436,671USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Revenue2,976,411USD2,500,284USD2,539,986USD1,706,925USD1,160,692USD436,942USD17,066USD0USD
    Gross Profit2,976,411USD2,500,284USD2,539,986USD1,706,925USD1,160,692USD436,942USD17,066USD-15,827USD
    Research Development3,065,484USD3,288,332USD3,494,765USD4,770,834USD3,163,485USD1,731,406USD4,889,340USD2,883,952USD
    Selling General Administrative2,745,509USD3,416,380USD3,560,936USD3,653,999USD3,743,972USD3,400,071USD4,731,176USD4,392,375USD
    Total Operating Expenses5,810,993USD6,704,712USD7,055,701USD8,424,833USD6,907,457USD14,374,605USD12,903,895USD7,276,327USD
    Operating Income-2,834,582USD-4,204,428USD-4,515,715USD-6,717,908USD-5,746,765USD-13,937,663USD-12,886,829USD-7,276,327USD
    Interest Income147,997USD249,861USD351,807USD167,152USD100,467USD126,171USD108,490USD510USD
    Net Interest Income147,997USD249,861USD351,807USD167,152USD100,467USD126,171USD108,489USD509USD
    Income Before Tax-2,680,860USD-3,960,275USD-4,134,578USD-6,552,353USD-5,645,179USD-13,811,984USD-12,775,025USD-7,300,458USD
    Net Income-2,680,860USD-3,960,275USD-4,134,578USD-6,552,353USD-5,645,179USD-10,893,466USD-12,775,025USD-7,300,458USD
    Net Income From Continuing Ops-2,680,860USD-3,960,275USD-4,445,607USD-6,552,353USD-5,645,179USD-10,893,466USD-12,775,025USD-7,300,458USD
    Ebitda-2,834,582USD-4,051,092USD-4,515,715USD-6,690,865USD-5,711,283USD-4,665,698USD-9,575,963USD-7,260,500USD
    Total Other Income Expense Net153,722USD244,153USD381,137USD165,555USD101,586USD125,679USD111,804USD-24,131USD
    Ebit—-4,204,428USD-4,487,792USD-6,717,908USD-5,746,765USD-4,694,535USD-9,603,450USD-7,276,327USD
    Depreciation And Amortization—153,336USD-28,208USD27,043USD35,482USD28,837USD27,487USD15,827USD
    Income Tax Expense——28,207USD-165,555USD-100,467USD-2,918,518USD3,174,890USD24,131USD
    Reconciled Depreciation——0USD27,043USD35,482USD28,837USD27,487USD15,827USD
    Cost Of Revenue———27,043USD35,482USD——15,827USD
    Interest Expense———165,555USD101,586USD18,360,577USD111,804USD24,131USD
    Tax Provision————0USD-2,918,518USD——
    Net Income Applicable To Common Shares————-5,645,179USD-10,893,466USD-18,059,404USD-7,300,458USD
    Unclassified Operating Expenses—————9,243,128USD3,283,379USD—
    Non Operating Income Net Other—————-492USD3,315USD-24,640USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets6,967,998USD7,908,991USD8,363,847USD5,067,960USD5,353,700USD5,791,217USD6,901,443USD8,046,000USD
    Cash And Equivalents6,471,766USD———————
    Total Current Assets6,654,077USD7,595,070USD8,049,926USD5,067,960USD5,353,700USD5,477,296USD6,587,522USD7,027,648USD
    Other Current Assets182,311USD247,815USD166,294USD946,361USD573,854USD313,620USD421,954USD188,088USD
    Other Non Current Assets313,921USD———————
    Total Liabilities894,977USD———————
    Total Current Liabilities894,977USD958,239USD968,025USD1,111,775USD903,430USD667,927USD894,263USD1,009,407USD
    Total Stockholder Equity6,073,021USD6,950,752USD7,395,822USD3,956,185USD4,450,270USD5,123,290USD6,007,180USD7,036,593USD
    Total Equity Including Noncontrolling Interest6,073,021USD———————
    Accounts Payable322,537USD558,808USD258,109USD578,250USD346,828USD240,293USD283,615USD243,343USD
    Common Stock2,346USD2,294USD2,294USD1,545USD1,545USD1,545USD1,545USD1,545USD
    Retained Earnings-201,261,408USD-200,331,713USD-199,875,331USD-199,296,255USD-198,786,315USD-198,097,612USD-197,194,471USD-196,139,950USD
    Accumulated Other Comprehensive Income253,734USD253,734USD253,734USD253,734USD253,734USD253,734USD253,734USD253,734USD
    Total Liab—958,239USD968,025USD1,111,775USD903,430USD667,927USD894,263USD1,009,407USD
    Other Current Liab—399,431USD709,916USD533,525USD556,602USD427,634USD610,648USD766,064USD
    Capital Stock—3,748USD3,748USD3,349USD3,349USD3,349USD3,349USD3,349USD
    Cash—7,347,255USD7,883,632USD4,121,599USD4,779,846USD5,163,676USD6,165,568USD6,839,560USD
    Cash And Short Term Investments—7,347,255USD7,883,632USD4,121,599USD4,779,846USD5,163,676USD6,165,568USD6,839,560USD
    Net Debt—-7,347,255USD-7,883,632USD-4,121,599USD-4,779,846USD-5,163,676USD-6,165,568USD-6,839,560USD
    Common Stock Shares Outstanding—2,291,056shares2,291,056shares1,542,139shares1,542,139shares1,542,139shares1,541,339shares1,541,722shares
    Non Current Assets Total—313,921USD313,921USD0USD0USD313,921USD313,921USD1,018,352USD
    Non Current Liabilities Total—0USD0USD0USD0USD0USD0USD0USD
    Non Currrent Assets Other—313,921USD313,921USD——313,921USD313,921USD1,018,352USD
    Net Working Capital—6,636,831USD7,081,901USD3,956,185USD4,450,270USD4,809,369USD5,693,259USD6,018,241USD
    Unclassified Equity—207,022,689USD207,011,377USD202,993,812USD202,977,957USD202,962,274USD202,943,023USD202,917,915USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Assets8,363,847USD6,901,443USD10,605,226USD14,720,290USD19,815,360USD13,179,495USD21,546,926USD14,431,094USD
    Other Current Assets166,294USD421,954USD603,828USD556,094USD479,399USD841,958USD722,079USD622,366USD
    Total Liab968,025USD894,263USD809,585USD1,073,156USD1,421,103USD963,971USD4,333,675USD4,518,306USD
    Total Stockholder Equity7,395,822USD6,007,180USD9,795,641USD13,647,134USD18,394,257USD12,215,524USD17,213,251USD9,912,788USD
    Other Current Liab709,916USD610,648USD568,753USD785,796USD1,031,590USD574,050USD463,987USD665,641USD
    Common Stock2,294USD1,545USD1,544USD1,520USD13,465USD8,771USD6,092USD9,726USD
    Capital Stock3,748USD3,349USD3,348USD17,966USD16,239USD11,545USD8,866USD12,500USD
    Retained Earnings-199,875,331USD-197,194,471USD-193,234,196USD-189,099,618USD-182,547,265USD-176,902,086USD-166,008,620USD-153,233,595USD
    Cash7,883,632USD6,165,568USD8,983,046USD13,097,265USD18,244,030USD11,527,552USD10,367,920USD571,605USD
    Cash And Short Term Investments7,883,632USD6,165,568USD8,983,046USD13,097,265USD18,244,030USD11,527,552USD10,367,920USD571,605USD
    Total Current Assets8,049,926USD6,587,522USD9,586,874USD13,653,359USD18,723,429USD12,369,510USD11,089,999USD1,193,971USD
    Total Current Liabilities968,025USD894,263USD809,585USD1,073,156USD1,421,103USD936,928USD1,415,157USD1,599,788USD
    Net Debt-7,883,632USD-6,165,568USD-8,983,046USD-13,097,265USD-18,216,987USD-11,465,027USD-10,347,878USD-571,605USD
    Accounts Payable258,109USD283,615USD240,832USD287,360USD362,470USD327,396USD931,128USD934,147USD
    Accumulated Other Comprehensive Income253,734USD253,734USD253,734USD253,734USD253,734USD253,734USD253,734USD253,734USD
    Common Stock Shares Outstanding1,701,571shares1,541,339shares1,528,210shares1,422,443shares1,027,940shares639,238shares285,246shares75,601shares
    Non Current Assets Total313,921USD313,921USD1,018,352USD1,066,931USD1,091,931USD809,985USD10,456,926USD13,237,123USD
    Non Current Liabilities Total0USD0USD0USD287,360USD362,470USD27,043USD2,918,518USD2,918,518USD
    Non Currrent Assets Other313,921USD313,921USD1,018,352USD1,066,931USD1,091,931USD782,942USD1,192,999USD705,660USD
    Net Working Capital7,081,901USD5,693,259USD8,777,289USD12,580,203USD17,302,326USD11,432,582USD9,674,842USD-405,817USD
    Unclassified Equity207,011,377USD202,943,023USD202,771,211USD202,473,532USD200,658,084USD194,124,740USD188,234,359USD168,151,603USD
    Other Assets————1,091,931USD809,985USD1,213,042USD705,660USD
    Current Deferred Revenue————-27,043USD-35,482USD-20,042USD—
    Short Term Debt————27,043USD35,482USD20,042USD—
    Short Long Term Debt Total————27,043USD62,525USD20,042USD—
    Property Plant Equipment Net————0USD27,043USD20,799USD4,956USD
    Property Plant Equipment Gross————50,243USD57,027USD57,027USD—
    Net Tangible Assets————18,391,483USD12,212,750USD7,967,349USD-2,616,493USD
    Unclassified Non Current Assets————-1,091,931USD—-10,456,170USD—
    Deferred Long Term Liab—————27,043USD2,918,518USD2,918,518USD
    Other Liab—————27,043USD2,918,518USD2,918,518USD
    Good Will—————0USD9,243,128USD3,283,379USD
    Net Receivables—————500,000USD——
    Treasury Stock—————-5,281,180USD-5,281,180USD-5,281,180USD
    Non Current Liabilities Other—————27,043USD——
    Intangible Assets——————9,243,128USD9,243,128USD
    Unclassified Non Current Liabilities——————-2,918,518USD-2,918,518USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-456,382USD-579,076USD-509,939USD-688,703USD-903,141USD-1,054,521USD-436,671USD-1,273,970USD
    Stock Based Compensation11,312USD13,998USD15,855USD15,683USD19,251USD25,108USD27,536USD42,096USD
    Other Non Cash Items11,312USD322,396USD15,854USD171,190USD19,251USD—615,562USD-829,012USD
    Change In Working Capital-91,307USD322,396USD-164,162USD289,190USD-118,002USD355,421USD-49,902USD706,770USD
    Total Cash From Operating Activities-536,377USD-242,682USD-658,247USD-383,830USD-1,001,892USD-673,992USD-459,037USD-525,104USD
    Capital Expenditures-3USD0USD-3USD0USD-2USD0USD0USD0USD
    Free Cash Flow-536,380USD-242,682USD-658,250USD-383,830USD-1,001,890USD-673,992USD-459,037USD-525,104USD
    Change In Cash-536,377USD3,762,033USD-658,247USD-383,830USD-1,001,892USD-673,992USD-459,037USD-525,104USD
    Begin Period Cash Flow7,883,632USD4,121,599USD4,779,846USD5,163,676USD6,165,568USD6,839,560USD7,298,597USD7,823,701USD
    End Period Cash Flow7,347,255USD7,883,632USD4,121,599USD4,779,846USD5,163,676USD6,165,568USD6,839,560USD7,298,597USD
    Total Cash From Financing Activities—4,004,715USD——————
    Other Cashflows From Financing Activities—4,004,715USD——————
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Net Income-2,680,860USD-3,960,275USD-4,134,578USD-6,552,353USD-5,645,179USD-10,893,466USD-12,775,025USD-7,300,458USD
    Stock Based Compensation64,787USD171,814USD283,085USD511,480USD410,437USD468,914USD853,517USD1,421,581USD
    Other Non Cash Items329,422USD970,983USD283,085USD1,793,750USD24,269USD9,099,489USD6,376,141USD-5,231USD
    Change In Working Capital329,422USD970,983USD-262,726USD-426,685USD461,193USD-52,449USD-881,524USD-595,676USD
    Total Cash From Operating Activities-2,286,651USD-2,817,478USD-4,114,219USD-4,646,765USD-4,738,067USD-4,267,193USD-6,399,404USD-6,463,957USD
    Capital Expenditures0USD0USD-1USD-500,000USD0USD0USD0USD0USD
    Free Cash Flow-2,286,651USD-2,817,478USD-4,114,220USD-5,146,765USD-4,738,067USD-4,267,193USD-6,399,404USD-6,463,957USD
    Total Cash From Financing Activities4,004,715USD1USD16USD1,293,750USD11,454,545USD5,426,825USD16,127,209USD1,480,000USD
    Issuance Of Capital Stock4,004,715USD1USD—0USD11,450,866USD5,426,825USD16,121,000USD—
    Change In Cash1,718,064USD-2,817,478USD-4,114,219USD-5,146,765USD6,716,478USD1,159,632USD9,729,805USD-4,961,457USD
    Begin Period Cash Flow6,165,568USD8,983,046USD13,097,265USD18,244,030USD11,527,552USD10,367,920USD638,115USD5,599,572USD
    End Period Cash Flow7,883,632USD6,165,568USD8,983,046USD13,097,265USD18,244,030USD11,527,552USD10,367,920USD638,115USD
    Other Cashflows From Financing Activities4,004,715USD—-16USD-500,000USD3,679USD5,426,825USD6,209USD1,480,000USD
    Unclassified Financing Cash Flow-4,004,715USD————-5,426,825USD13,089,774USD-1,480,000USD
    Depreciation——0USD27,043USD35,482USD28,837USD27,487USD15,827USD
    Investments——0USD-500,000USD0USD0USD2,000USD22,500USD
    Total Cashflows From Investing Activities———-500,000USD——2,000USD22,500USD
    Sale Purchase Of Stock———1,293,750USD—5,426,825USD3,031,226USD1,480,000USD
    Other Cashflows From Investing Activities———500,000USD——2,000USD22,500USD
    Change To Liabilities————457,132USD-378,111USD-227,961USD-343,878USD
    Cash And Cash Equivalents Changes—————1,159,632USD9,729,805USD-4,961,457USD
    Unclassified Operating Cash Flow—————-2,918,518USD——
    Change To Account Receivables———————0USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    PeriodDimensionBusiness / regionRevenueCurrencySource
    FY 2019Yearly · 2019-12-31ProductCodevelopment Agr0USD0001683168-20-000967
    FY 2019Yearly · 2019-12-31ProductRoyalty17,066USD0001683168-20-000967
    FY 2019Yearly · 2019-12-31ProductRoyalty Revenue0USD0001683168-20-000967
    FY 2017Yearly · 2017-12-31ProductCodevelopment Agr0USD0001683168-19-000840
    FY 2017Yearly · 2017-12-31ProductLicense7,500,000USD0001683168-19-000840
    FY 2017Yearly · 2017-12-31ProductRoyalty Revenue0USD0001683168-19-000840
    FY 2017Yearly · 2017-12-31ProductServices85,000USD0001683168-19-000840

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.