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    PTCT

    PTC THERAPEUTICS, INC.

    Company overview

    Market capitalization
    $5.50B
    Employees
    991
    Latest publication
    2026-09-29
    About PTC THERAPEUTICS, INC.

    PTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to children and adults living with rare disorders in the United States and internationally. The company provides Translarna and Emflaza for the treatment of Duchenne muscular dystrophy; Upstaza to treat aromatic l-amino acid decarboxylas (AADC) deficiency, a central nervous system disorder; Tegsedi and Waylivra for the treatment of rare diseases; and Evrysdi to treat spinal muscular atrophy (SMA) in adults and children. Its development pipeline products include Sepiapterin for the treatment of phenylketonuria; PTC518 splicing platform, which is being developed for the treatment of Huntington's disease; and inflammation and ferroptosis platforms, including vatiquinone to treat Friedreich's ataxia. The company distributes its products through third-party distributors. It has collaborations with F. Hoffman-La Roche Ltd., Hoffman-La Roche Inc., the SMA Foundation, National Taiwan University, Akcea Therapeutics, Inc., and Shiratori Pharmaceutical Co., Ltd. The company has license and collaboration agreement with Novartis Pharmaceuticals Corporation to develop PTC518 Huntington's disease program. It markets Upstaza, a gene therapy with the brand name Kebilidi in the United States. PTC Therapeutics, Inc. was incorporated in 1998 and is headquartered in Warren, New Jersey.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ3 20252025-09-30 · USDQ1 20252025-03-31 · USDQ4 20232023-12-31 · USDQ2 20172017-06-30 · USDQ1 20172017-03-31 · USDQ3 20162016-09-30 · USD
    Total Revenue360,519,000USD272,551,000USD211,007,000USD1,176,096,000USD307,056,000USD47,962,000USD26,547,000USD22,986,000USD
    Research Development99,150,000USD100,873,000USD100,158,000USD108,973,000USD121,353,000USD30,835,000USD27,363,000USD31,396,000USD
    Selling General Administrative80,630,000USD86,183,000USD84,046,000USD80,961,000USD80,886,000USD28,866,000USD25,500,000USD23,654,000USD
    Total Operating Expenses211,542,000USD187,056,000USD92,052,000USD193,009,000USD197,644,000USD59,701,000USD52,863,000USD55,050,000USD
    Operating Income148,977,000USD45,886,000USD3,016,000USD970,225,000USD3,120,000USD-12,497,000USD-26,355,000USD-32,064,000USD
    Total Other Income Expense Net-51,432,000USD-48,348,000USD-26,090,000USD-40,397,000USD-160,171,000USD-4,828,000USD-2,537,000USD-2,919,000USD
    Income Before Tax97,545,000USD-2,462,000USD-23,074,000USD929,828,000USD-157,051,000USD-17,325,000USD-28,892,000USD-34,983,000USD
    Income Tax Expense14,049,000USD347,000USD-38,970,000USD63,266,000USD-1,259,000USD150,000USD165,000USD184,000USD
    Net Income83,496,000USD-2,809,000USD15,896,000USD866,562,000USD-155,792,000USD-17,475,000USD-29,057,000USD-35,167,000USD
    Net Income Applicable To Common Shares84,455,000USD————-17,475,000USD-29,057,000USD-35,167,000USD
    Cost Of Revenue—39,609,000USD115,939,000USD12,862,000USD106,292,000USD758,000USD39,000USD31,396,000USD
    Gross Profit—232,942,000USD95,068,000USD1,163,234,000USD200,764,000USD47,204,000USD26,508,000USD-8,410,000USD
    Interest Expense—49,030,000USD32,592,000USD34,092,000USD44,275,000USD3,008,000USD2,219,000USD2,133,000USD
    Net Interest Income—-49,030,000USD-32,592,000USD-34,092,000USD-44,275,000USD———
    Tax Provision—347,000USD-38,970,000USD63,266,000USD-1,259,000USD———
    Net Income From Continuing Ops—-2,809,000USD15,896,000USD866,562,000USD-155,792,000USD-17,475,000USD-29,057,000USD-35,167,000USD
    Ebit—-51,492,000USD9,518,000USD963,920,000USD-112,776,000USD-12,497,000USD-26,355,000USD-32,064,000USD
    Ebitda—-36,079,000USD20,627,000USD971,141,000USD-32,071,000USD-11,661,000USD-25,743,000USD-31,251,000USD
    Depreciation And Amortization—15,413,000USD11,109,000USD7,221,000USD80,705,000USD836,000USD612,000USD813,000USD
    Reconciled Depreciation—15,413,000USD11,109,000USD7,221,000USD80,705,000USD836,000USD612,000USD813,000USD
    Unclassified Operating Expenses——-92,152,000USD3,075,000USD-4,595,000USD———
    Non Operating Income Net Other—————-1,820,000USD-318,000USD-786,000USD
    Minority Interest—————0USD0USD0USD
    Discontinued Operations—————0USD0USD0USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20162016-12-31 · USDFY 20152015-12-31 · USDFY 20142014-12-31 · USDFY 20112011-12-31 · USDFY 20052005-12-31 · USDFY 20042004-12-31 · USD
    Total Revenue1,730,655,000USD82,705,000USD36,766,000USD22,963,000USD98,960,851USD4,967,000USD1,606,000USD
    Cost Of Revenue71,755,000USD117,633,000USD121,816,000USD79,838,000USD71,959,000USD27,601,000USD24,656,000USD
    Gross Profit1,658,900,000USD82,705,000USD36,766,000USD-56,875,000USD98,960,851USD——
    Research Development455,249,000USD117,633,000USD121,816,000USD79,838,000USD58,677,081USD21,123,000USD20,070,000USD
    Selling General Administrative347,143,000USD97,130,000USD82,080,000USD44,820,000USD16,153,069USD——
    Total Operating Expenses802,392,000USD214,763,000USD203,896,000USD122,376,000USD68,378,854USD——
    Operating Income856,508,000USD-132,058,000USD-167,130,000USD-99,413,000USD30,581,997USD——
    Interest Expense152,230,000USD8,276,000USD2,367,000USD1,180,000USD2,444,417USD0USD0USD
    Net Interest Income-152,230,000USD-8,276,000USD—————
    Income Before Tax696,619,000USD-141,541,000USD-169,962,000USD-98,446,000USD28,598,938USD——
    Income Tax Expense13,975,000USD569,000USD485,000USD-4,693,000USD-2,305,576USD——
    Tax Provision13,975,000USD569,000USD485,000USD————
    Net Income682,644,000USD-142,110,000USD-170,447,000USD-93,753,000USD30,904,514USD——
    Net Income From Continuing Ops682,644,000USD-142,110,000USD-170,447,000USD-93,753,000USD———
    Ebit848,849,000USD-132,058,000USD-167,130,000USD-99,413,000USD30,581,997USD——
    Ebitda887,664,000USD-128,768,000USD-164,254,000USD-97,178,000USD33,453,197USD——
    Depreciation And Amortization38,815,000USD3,290,000USD2,876,000USD2,235,000USD2,871,200USD——
    Reconciled Depreciation38,815,000USD——————
    Total Other Income Expense Net-159,889,000USD-1,207,000USD-465,000USD-213,000USD-1,983,059USD——
    Interest Income—8,276,000USD2,367,000USD————
    Non Operating Income Net Other—-1,207,000USD-465,000USD-213,000USD———
    Net Income Applicable To Common Shares—-142,110,000USD-170,447,000USD-93,753,000USD30,905,000USD——
    Unclassified Operating Expenses———-2,282,000USD-6,451,296USD——
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets3,250,477,000USD2,869,104,000USD2,911,250,000USD2,643,700,000USD2,634,155,000USD2,655,387,000USD1,705,024,000USD1,842,236,000USD
    Cash And Equivalents1,049,887,000USD———————
    Cash And Short Term Investments2,229,082,000USD1,892,463,000USD1,945,371,000USD1,687,817,000USD1,989,150,000USD2,027,181,000USD1,139,696,000USD1,013,357,000USD
    Short Term Investments1,179,195,000USD1,058,477,000USD960,723,000USD1,015,200,000USD971,764,000USD546,950,000USD359,987,000USD487,356,000USD
    Total Current Assets2,617,359,000USD2,254,003,000USD2,273,948,000USD2,007,803,000USD2,272,875,000USD2,316,406,000USD1,365,531,000USD1,281,550,000USD
    Other Current Assets57,879,000USD66,054,000USD67,309,000USD64,224,000USD53,531,000USD57,055,000USD44,087,000USD32,546,000USD
    Total Liabilities3,415,840,000USD———————
    Total Current Liabilities771,068,000USD923,604,000USD968,427,000USD866,245,000USD627,809,000USD595,391,000USD580,981,000USD610,712,000USD
    Other Non Current Liabilities14,501,000USD———————
    Total Stockholder Equity-165,363,000USD-180,465,000USD-205,313,000USD-155,758,000USD-206,546,000USD-185,760,000USD-1,098,071,000USD-1,054,352,000USD
    Total Equity Including Noncontrolling Interest-165,363,000USD———————
    Short Long Term Debt55,451,000USD286,937,000USD569,631,000USD286,319,000USD——257,821,000USD—
    Long Term Debt535,519,000USD—2,025,366,000USD—286,013,000USD285,712,000USD2,109,367,000USD285,106,000USD
    Deferred Revenue1,192,000USD———————
    Inventory91,354,000USD75,567,000USD79,647,000USD52,688,000USD34,061,000USD21,675,000USD23,194,000USD35,671,000USD
    Property Plant Equipment Net126,270,000USD129,431,000USD135,424,000USD137,652,000USD113,351,000USD116,776,000USD117,655,000USD122,640,000USD
    Goodwill82,341,000USD———————
    Intangible Assets402,926,000USD380,684,000USD388,753,000USD396,466,000USD143,806,000USD118,448,000USD118,794,000USD330,368,000USD
    Accounts Payable40,447,000USD25,484,000USD45,487,000USD36,617,000USD26,505,000USD15,150,000USD17,274,000USD13,292,000USD
    Short Term Debt11,965,000USD305,015,000USD302,115,000USD300,805,000USD17,083,000USD16,511,000USD271,184,000USD16,755,000USD
    Common Stock82,000USD81,000USD80,000USD79,000USD78,000USD78,000USD77,000USD76,000USD
    Retained Earnings-2,883,542,000USD-2,967,038,000USD-2,964,229,000USD-2,829,264,000USD-2,845,160,000USD-2,780,311,000USD-3,646,873,000USD-3,580,987,000USD
    Accumulated Other Comprehensive Income6,017,000USD8,466,000USD10,501,000USD5,930,000USD7,356,000USD-13,949,000USD-25,886,000USD-4,343,000USD
    Total Liab—3,049,569,000USD3,116,563,000USD2,799,458,000USD2,840,701,000USD2,841,147,000USD2,803,095,000USD2,896,588,000USD
    Other Current Liab—592,607,000USD618,785,000USD527,132,000USD534,538,000USD486,275,000USD282,317,000USD574,653,000USD
    Capital Stock—81,000USD80,000USD79,000USD78,000USD78,000USD77,000USD76,000USD
    Good Will—82,341,000USD82,341,000USD82,341,000USD82,341,000USD82,341,000USD82,341,000USD82,341,000USD
    Other Assets—1USD————-11,740,000USD—
    Cash—833,986,000USD984,648,000USD672,617,000USD1,017,386,000USD1,480,231,000USD779,709,000USD526,001,000USD
    Current Deferred Revenue—498,000USD2,040,000USD1,691,000USD9,760,000USD12,833,000USD5,505,000USD—
    Net Debt—-438,899,000USD-492,367,000USD-167,003,000USD-629,220,000USD-1,090,616,000USD1,691,363,000USD-125,796,000USD
    Short Long Term Debt Total—395,087,000USD492,281,000USD505,614,000USD388,166,000USD389,615,000USD2,471,072,000USD400,205,000USD
    Net Receivables—219,919,000USD181,621,000USD203,074,000USD196,133,000USD210,495,000USD158,554,000USD199,976,000USD
    Property Plant Equipment Gross—129,431,000USD182,417,000USD137,652,000USD113,351,000USD116,776,000USD151,013,000USD122,640,000USD
    Common Stock Shares Outstanding—82,521,023shares80,689,810shares87,115,369shares78,151,240shares86,385,922shares77,201,783shares76,925,523shares
    Non Current Assets Total—615,100,999USD637,302,000USD635,896,999USD361,280,000USD338,981,000USD339,493,000USD560,686,000USD
    Non Current Liabilities Total—2,125,965,000USD2,148,136,000USD1,933,213,000USD2,212,892,000USD2,245,756,000USD2,222,114,000USD2,285,876,000USD
    Non Current Liabilities Other—2,035,893,000USD13,704,000USD1,823,892,000USD1,841,809,000USD1,872,652,000USD21,426,000USD1,824,517,000USD
    Non Currrent Assets Other—6,195,999USD4,615,000USD5,754,999USD21,782,000USD21,416,000USD20,703,000USD25,337,000USD
    Net Working Capital—1,330,399,000USD1,305,521,000USD1,141,558,000USD1,645,066,000USD1,721,015,000USD784,550,000USD670,838,000USD
    Unclassified Non Current Assets—16,448,999USD26,169,000USD13,683,000USD————
    Unclassified Current Liabilities—-286,937,000USD-569,631,000USD-286,319,000USD39,923,000USD64,622,000USD-253,120,000USD—
    Unclassified Non Current Liabilities—90,072,000USD109,066,000USD109,321,000USD85,070,000USD87,392,000USD91,321,000USD176,253,000USD
    Unclassified Equity—2,777,945,000USD2,748,255,000USD2,667,418,000USD2,631,102,000USD2,608,344,000USD2,574,534,000USD2,530,826,000USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Assets2,911,250,000USD1,705,024,000USD1,895,698,000USD1,705,619,000USD1,938,056,000USD2,208,278,000USD1,623,782,000USD1,119,222,000USD
    Intangible Assets388,753,000USD118,794,000USD379,497,000USD705,891,000USD724,841,000USD715,328,000USD710,500,000USD701,031,000USD
    Other Current Assets67,309,000USD44,087,000USD150,491,000USD105,658,000USD-126,311,000USD39,469,000USD17,898,000USD18,494,000USD
    Total Liab3,116,563,000USD2,803,095,000USD2,714,253,000USD2,052,705,000USD1,936,618,000USD1,726,296,000USD1,029,452,000USD768,495,000USD
    Total Stockholder Equity-205,313,000USD-1,098,071,000USD-818,555,000USD-347,086,000USD1,438,000USD481,982,000USD594,330,000USD350,727,000USD
    Other Current Liab618,785,000USD282,317,000USD385,938,000USD288,386,000USD60,751,000USD241,461,000USD191,639,000USD145,412,000USD
    Common Stock80,000USD77,000USD75,000USD72,000USD71,000USD70,000USD62,000USD51,000USD
    Capital Stock80,000USD77,000USD75,000USD72,000USD71,000USD70,000USD62,000USD51,000USD
    Retained Earnings-2,964,229,000USD-3,646,873,000USD-3,283,578,000USD-2,656,974,000USD-2,097,957,000USD-1,628,877,000USD-1,190,499,000USD-938,923,000USD
    Good Will82,341,000USD82,341,000USD82,341,000USD82,341,000USD82,341,000USD82,341,000USD82,341,000USD82,341,000USD
    Cash984,648,000USD779,709,000USD594,001,000USD279,834,000USD773,376,000USD208,812,000USD288,028,000USD227,586,000USD
    Cash And Short Term Investments1,945,371,000USD1,139,696,000USD876,739,000USD410,705,000USD773,376,000USD1,103,650,000USD686,563,000USD227,586,000USD
    Total Current Assets2,273,948,000USD1,365,531,000USD1,218,629,000USD693,785,000USD773,376,000USD1,231,745,000USD779,284,000USD320,857,000USD
    Total Current Liabilities968,427,000USD580,981,000USD603,100,000USD406,236,000USD509,348,000USD277,333,000USD235,857,000USD166,796,000USD
    Current Deferred Revenue2,040,000USD5,505,000USD801,000USD1,351,000USD265,751,000USD4,151,000USD8,242,000USD3,716,000USD
    Net Debt-492,367,000USD1,691,363,000USD1,635,122,000USD1,181,679,000USD-341,942,000USD211,626,000USD40,002,000USD-74,572,000USD
    Short Term Debt302,115,000USD271,184,000USD210,316,000USD84,519,000USD159,813,000USD8,741,000USD25,153,000USD11,667,000USD
    Short Long Term Debt569,631,000USD257,821,000USD194,314,000USD72,149,000USD149,540,000USD—20,000,000USD11,667,000USD
    Short Long Term Debt Total492,281,000USD2,471,072,000USD2,229,123,000USD1,461,513,000USD441,707,000USD420,438,000USD328,030,000USD153,014,000USD
    Long Term Debt2,025,366,000USD2,109,367,000USD1,903,996,000USD571,722,000USD281,894,000USD309,145,000USD293,859,000USD141,347,000USD
    Short Term Investments960,723,000USD359,987,000USD282,738,000USD130,871,000USD583,658,000USD894,838,000USD398,535,000USD58,088,000USD
    Net Receivables181,621,000USD158,554,000USD160,822,000USD155,614,000USD110,455,000USD69,929,000USD55,538,000USD67,907,000USD
    Inventory79,647,000USD23,194,000USD30,577,000USD21,808,000USD15,856,000USD18,697,000USD19,285,000USD16,117,000USD
    Accounts Payable45,487,000USD17,274,000USD6,045,000USD27,268,000USD23,033,000USD18,665,000USD10,324,000USD6,001,000USD
    Property Plant Equipment Net135,424,000USD117,655,000USD178,985,000USD175,020,000USD130,006,000USD118,241,000USD35,242,000USD12,694,000USD
    Property Plant Equipment Gross182,417,000USD151,013,000USD230,259,000USD212,388,000USD157,179,000USD118,241,000USD21,549,000USD12,694,000USD
    Accumulated Other Comprehensive Income10,501,000USD-25,886,000USD-1,285,000USD4,796,000USD-24,282,000USD-60,957,000USD-10,584,000USD1,462,000USD
    Common Stock Shares Outstanding88,311,494shares76,845,055shares74,838,392shares71,728,634shares70,466,393shares66,027,908shares58,863,185shares46,576,313shares
    Non Current Assets Total637,302,000USD339,493,000USD677,069,000USD1,011,834,000USD1,164,680,000USD976,533,000USD844,498,000USD798,365,000USD
    Non Current Liabilities Total2,148,136,000USD2,222,114,000USD2,111,153,000USD1,646,469,000USD1,165,419,000USD1,448,963,000USD793,595,000USD601,699,000USD
    Non Current Liabilities Other13,704,000USD21,426,000USD141,000USD971,913,000USD1,008,266,000USD1,003,083,000USD368,874,000USD338,320,000USD
    Non Currrent Assets Other4,615,000USD20,703,000USD36,246,000USD48,582,000USD227,492,000USD60,623,000USD16,415,000USD2,299,000USD
    Net Working Capital1,305,521,000USD784,550,000USD615,529,000USD287,549,000USD445,020,000USD954,412,000USD543,427,000USD154,061,000USD
    Unclassified Non Current Assets26,169,000USD——-33,382,000USD-46,500,000USD-60,623,000USD-16,415,000USD—
    Unclassified Current Liabilities-569,631,000USD-253,120,000USD-194,314,000USD-67,437,000USD-149,540,000USD4,315,000USD-19,501,000USD-11,667,000USD
    Unclassified Non Current Liabilities109,066,000USD91,321,000USD207,016,000USD-269,475,000USD-1,313,555,000USD-1,037,266,000USD-490,718,000USD-460,352,000USD
    Unclassified Equity2,748,255,000USD2,574,534,000USD2,466,158,000USD2,304,948,000USD2,123,535,000USD2,171,676,000USD1,795,289,000USD1,288,086,000USD
    Deferred Long Term Liab———102,834,000USD137,110,000USD136,735,000USD130,862,000USD122,032,000USD
    Other Liab———269,475,000USD1,051,704,000USD1,037,266,000USD490,718,000USD460,352,000USD
    Other Assets———33,382,000USD46,500,000USD60,623,000USD16,415,000USD2,299,000USD
    Net Tangible Assets———-1,135,318,000USD-805,744,000USD-315,687,000USD-198,511,000USD-432,645,000USD
    Unclassified Current Assets————-709,969,000USD——-67,335,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow YTD

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USD
    Depreciation31,287,000USD
    Stock Based Compensation46,712,000USD
    Change To Inventory-13,217,000USD
    Change To Liabilities-35,338,000USD
    Change In Working Capital-39,011,000USD
    Operating Cash Flow70,071,000USD
    Capital Expenditures-3,389,000USD
    Net Investments-207,795,000USD
    Unclassified Investing Cash Flow-5,108,000USD
    Investing Cash Flow-216,292,000USD
    Common Stock Issuance3,163,000USD
    Unclassified Financing Cash Flow215,118,000USD
    Financing Cash Flow218,281,000USD
    Effect Of Forex Changes On Cash-4,062,000USD
    Change In Cash67,998,000USD
    End Cash Flow1,066,332,000USD
    SourceDisclosureDeterministicFinal

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-2,809,000USD-134,965,000USD15,896,000USD-64,849,000USD866,562,000USD-65,886,000USD-106,654,000USD-99,179,000USD
    Depreciation15,413,000USD12,902,000USD11,109,000USD7,583,000USD7,221,000USD6,764,000USD6,486,000USD7,018,000USD
    Stock Based Compensation23,421,000USD18,518,000USD19,426,000USD18,543,000USD18,060,000USD17,239,000USD19,755,000USD19,243,000USD
    Other Non Cash Items15,642,000USD-21,842,000USD-27,852,000USD-2,888,000USD15,655,000USD31,210,000USD-8,208,000USD12,641,000USD
    Change To Account Receivables-40,390,000USD22,214,000USD-6,474,000USD21,901,000USD-47,792,000USD40,761,000USD-7,719,000USD8,190,000USD
    Change To Inventory2,643,000USD-26,779,000USD-18,526,000USD-10,782,000USD2,191,000USD11,086,000USD-3,106,000USD-1,936,000USD
    Change In Working Capital-110,699,000USD91,113,000USD-84,876,000USD-16,720,000USD-37,397,000USD36,579,000USD11,632,000USD-11,178,000USD
    Total Cash From Operating Activities-59,042,000USD-34,273,000USD-66,301,000USD-58,333,000USD870,103,000USD-30,004,000USD-76,992,000USD-71,453,000USD
    Capital Expenditures-1,353,000USD-37,291,000USD-3,445,000USD-3,994,000USD-2,532,000USD-6,497,000USD-10,776,000USD7,375,000USD
    Free Cash Flow-60,395,000USD-71,564,000USD-69,746,000USD-62,327,000USD867,571,000USD-36,501,000USD-87,768,000USD-64,078,000USD
    Investments-92,383,000USD71,299,000USD-289,623,000USD-422,009,000USD-184,360,000USD267,712,000USD-42,675,000USD-65,923,000USD
    Total Cashflows From Investing Activities-93,736,000USD34,008,000USD-289,623,000USD-422,009,000USD-184,360,000USD267,712,000USD-42,675,000USD-65,923,000USD
    Total Cash From Financing Activities6,403,000USD302,504,000USD15,219,000USD3,961,000USD9,410,000USD26,471,000USD-17,627,000USD246,482,000USD
    Change In Cash-150,662,000USD312,031,000USD-344,769,000USD-462,793,000USD700,546,000USD255,526,000USD-128,752,000USD103,919,000USD
    Begin Period Cash Flow984,648,000USD672,617,000USD1,017,386,000USD1,495,862,000USD795,316,000USD539,790,000USD668,542,000USD564,623,000USD
    End Period Cash Flow833,986,000USD984,648,000USD672,617,000USD1,033,069,000USD1,495,862,000USD795,316,000USD539,790,000USD668,542,000USD
    Other Cashflows From Investing Activities-156,000USD-34,917,000USD-252,750,000USD-2,677,000USD-738,000USD147,270,000USD-10,236,000USD28,038,000USD
    Net Borrowings—0USD-1,611,000USD0USD0USD0USD0USD—
    Other Cashflows From Financing Activities—240,000,000USD15,219,000USD3,961,000USD-6,341,000USD-1,490,000USD-17,627,000USD246,482,000USD
    Unclassified Investing Cash Flow—34,917,000USD256,195,000USD6,671,000USD3,270,000USD-140,773,000USD21,012,000USD-35,413,000USD
    Unclassified Financing Cash Flow—62,504,000USD1,611,000USD—15,751,000USD27,961,000USD——
    Unclassified Operating Cash Flow—————-55,910,000USD——
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Net Income682,644,000USD-363,295,000USD-626,604,000USD-559,017,000USD-523,901,000USD-438,160,000USD-251,576,000USD-128,081,000USD
    Depreciation38,815,000USD75,663,000USD236,590,000USD128,836,000USD64,134,000USD84,872,000USD32,180,000USD26,087,000USD
    Stock Based Compensation74,547,000USD74,615,000USD131,206,000USD110,333,000USD103,513,000USD70,325,000USD42,134,000USD33,252,000USD
    Other Non Cash Items-36,927,000USD58,698,000USD151,323,000USD82,805,000USD128,333,000USD46,109,000USD49,367,000USD27,382,000USD
    Change To Account Receivables-10,151,000USD1,732,000USD-1,539,000USD-48,468,000USD-44,991,000USD-10,483,000USD11,525,000USD-29,589,000USD
    Change To Inventory-53,896,000USD6,164,000USD-8,183,000USD-6,668,000USD1,800,000USD1,841,000USD-3,456,000USD-5,823,000USD
    Change In Working Capital-47,880,000USD102,543,000USD-4,003,000USD-85,335,000USD-23,788,000USD36,911,000USD20,427,000USD14,209,000USD
    Total Cash From Operating Activities711,196,000USD-107,688,000USD-158,418,000USD-356,654,000USD-251,332,000USD-194,071,000USD-98,639,000USD-27,641,000USD
    Capital Expenditures-8,860,000USD-74,249,000USD-120,619,000USD-152,460,000USD-85,331,000USD-55,977,000USD-45,439,000USD-15,530,000USD
    Free Cash Flow702,336,000USD-181,937,000USD-279,037,000USD-509,114,000USD-336,663,000USD-250,048,000USD-144,078,000USD-43,171,000USD
    Investments-562,042,000USD44,182,000USD-49,880,000USD442,641,000USD304,513,000USD-505,571,000USD-341,798,000USD21,809,000USD
    Total Cashflows From Investing Activities-861,984,000USD44,182,000USD-176,737,000USD290,181,000USD219,182,000USD-561,548,000USD-387,237,000USD-42,613,000USD
    Net Borrowings-1,611,000USD-1,490,000USD-301,379,000USD138,546,000USD-2,224,000USD-28,930,000USD267,600,000USD267,600,000USD
    Total Cash From Financing Activities331,094,000USD255,866,000USD646,400,000USD167,952,000USD20,877,000USD668,715,000USD613,209,000USD131,571,000USD
    Change In Cash204,939,000USD185,032,000USD314,359,000USD98,707,000USD-19,094,000USD-79,216,000USD126,030,000USD57,706,000USD
    Begin Period Cash Flow779,709,000USD610,284,000USD295,925,000USD197,218,000USD216,312,000USD295,528,000USD169,498,000USD111,792,000USD
    End Period Cash Flow984,648,000USD795,316,000USD610,284,000USD295,925,000USD197,218,000USD216,312,000USD295,528,000USD169,498,000USD
    Other Cashflows From Financing Activities232,048,000USD257,356,000USD947,779,000USD-30,772,000USD23,101,000USD686,785,000USD21,853,000USD13,655,000USD
    Unclassified Investing Cash Flow-291,082,000USD-36,060,000USD85,943,000USD128,436,000USD57,118,000USD38,134,000USD373,480,000USD-62,268,000USD
    Unclassified Financing Cash Flow100,657,000USD——-10,904,000USD-23,101,000USD-92,714,000USD-21,853,000USD-281,255,000USD
    Issuance Of Capital Stock—0USD0USD50,000,000USD0USD28,092,000USD323,756,000USD117,916,000USD
    Other Cashflows From Investing Activities—110,309,000USD-92,181,000USD-128,436,000USD-57,118,000USD-38,134,000USD-373,480,000USD13,376,000USD
    Unclassified Operating Cash Flow—-55,912,000USD-46,930,000USD-34,276,000USD—5,872,000USD8,829,000USD—
    Change To Liabilities———22,984,000USD41,649,000USD66,868,000USD40,504,000USD45,809,000USD
    Sale Purchase Of Stock———71,082,000USD23,101,000USD103,574,000USD345,609,000USD131,571,000USD
    Cash And Cash Equivalents Changes———101,479,000USD-11,273,000USD-86,904,000USD126,030,000USD57,706,000USD
    Exchange Rate Changes——————-1,303,000USD-3,611,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    PeriodDimensionBusiness / regionRevenueCurrencySource
    Q2 2026Quarterly · 2026-06-30ProductCollaboration And License Revenue50,595,000USDDisclosure
    Q2 2026Quarterly · 2026-06-30ProductEmflaza24,634,000USDDisclosure
    Q2 2026Quarterly · 2026-06-30ProductOther Products9,495,000USDDisclosure
    Q2 2026Quarterly · 2026-06-30ProductRoyalty71,105,000USDDisclosure
    Q2 2026Quarterly · 2026-06-30ProductSephience151,310,000USDDisclosure
    Q2 2026Quarterly · 2026-06-30ProductTranslarna42,217,000USDDisclosure
    Q2 2026Quarterly · 2026-06-30ProductUpstaza And Kebilidi11,163,000USDDisclosure
    Q1 2026Quarterly · 2026-03-31ProductCollaboration And License Revenue100,000USD0001070081-26-000012
    Q1 2026Quarterly · 2026-03-31ProductEmflaza21,478,000USD0001070081-26-000012
    Q1 2026Quarterly · 2026-03-31ProductOther Products10,974,000USD0001070081-26-000012
    Q1 2026Quarterly · 2026-03-31ProductRoyalty46,800,000USD0001070081-26-000012
    Q1 2026Quarterly · 2026-03-31ProductSephience124,551,000USD0001070081-26-000012
    Q1 2026Quarterly · 2026-03-31ProductTranslarna58,976,000USD0001070081-26-000012
    Q1 2026Quarterly · 2026-03-31ProductUpstaza And Kebilidi9,594,000USD0001070081-26-000012
    Q3 2025Quarterly · 2025-09-30ProductCollaboration And License Revenue9,300,000USD0001070081-25-000028
    Q3 2025Quarterly · 2025-09-30ProductEmflaza35,160,000USD0001070081-25-000028
    Q3 2025Quarterly · 2025-09-30ProductManufacturing0USD0001070081-25-000028
    Q3 2025Quarterly · 2025-09-30ProductOther Products9,833,000USD0001070081-25-000028
    Q3 2025Quarterly · 2025-09-30ProductRoyalty70,800,000USD0001070081-25-000028
    Q3 2025Quarterly · 2025-09-30ProductSephience19,563,000USD0001070081-25-000028
    Q3 2025Quarterly · 2025-09-30ProductTranslarna50,665,000USD0001070081-25-000028
    Q3 2025Quarterly · 2025-09-30ProductUpstaza15,735,000USD0001070081-25-000028
    Q2 2025Quarterly · 2025-06-30ProductCollaboration And License Revenue2,900,000USD0001558370-25-010796
    Q2 2025Quarterly · 2025-06-30ProductEmflaza36,353,000USD0001558370-25-010796
    Q2 2025Quarterly · 2025-06-30ProductManufacturing0USD0001558370-25-010796
    Q2 2025Quarterly · 2025-06-30ProductOther Products10,617,000USD0001558370-25-010796
    Q2 2025Quarterly · 2025-06-30ProductRoyalty57,600,000USD0001558370-25-010796
    Q2 2025Quarterly · 2025-06-30ProductTranslarna59,470,000USD0001558370-25-010796
    Q2 2025Quarterly · 2025-06-30ProductUpstaza11,889,000USD0001558370-25-010796
    Q1 2025Quarterly · 2025-03-31ProductCollaboration And License Revenue989,800,000USD0001070081-26-000012
    Q1 2025Quarterly · 2025-03-31ProductEmflaza47,789,000USD0001070081-26-000012
    Q1 2025Quarterly · 2025-03-31ProductOther Products10,824,000USD0001070081-26-000012
    Q1 2025Quarterly · 2025-03-31ProductRoyalty36,400,000USD0001070081-26-000012
    Q1 2025Quarterly · 2025-03-31ProductTranslarna86,154,000USD0001070081-26-000012
    Q1 2025Quarterly · 2025-03-31ProductUpstaza And Kebilidi8,659,000USD0001070081-26-000012
    FY 2024Yearly · 2024-12-31ProductCollaboration And License Revenue0USD0001104659-26-017575
    FY 2024Yearly · 2024-12-31ProductEmflaza207,215,000USD0001104659-26-017575
    FY 2024Yearly · 2024-12-31ProductManufacturing1,700,000USD0001104659-26-017575
    FY 2024Yearly · 2024-12-31ProductOther Products36,946,000USD0001104659-26-017575
    FY 2024Yearly · 2024-12-31ProductRoyalty203,900,000USD0001104659-26-017575
    FY 2024Yearly · 2024-12-31ProductTranslarna18,806,000USD0001104659-26-017575
    FY 2024Yearly · 2024-12-31ProductTranslarna1321,071,000USD0001104659-26-017575
    FY 2024Yearly · 2024-12-31ProductUpstaza And Kebilidi16,913,000USD0001104659-26-017575
    Q3 2024Quarterly · 2024-09-30ProductEmflaza51,941,000USD0001070081-25-000028
    Q3 2024Quarterly · 2024-09-30ProductManufacturing0USD0001070081-25-000028
    Q3 2024Quarterly · 2024-09-30ProductOther Products11,197,000USD0001070081-25-000028
    Q3 2024Quarterly · 2024-09-30ProductRoyalty61,400,000USD0001070081-25-000028
    Q3 2024Quarterly · 2024-09-30ProductTranslarna72,283,000USD0001070081-25-000028
    Q2 2024Quarterly · 2024-06-30ProductCollaboration And License Revenue0USD0001558370-25-010796
    Q2 2024Quarterly · 2024-06-30ProductEmflaza47,296,000USD0001558370-25-010796
    Q2 2024Quarterly · 2024-06-30ProductManufacturing300,000USD0001558370-25-010796
    Q2 2024Quarterly · 2024-06-30ProductOther Products13,985,000USD0001558370-25-010796
    Q2 2024Quarterly · 2024-06-30ProductRoyalty53,200,000USD0001558370-25-010796
    Q2 2024Quarterly · 2024-06-30ProductTranslarna70,350,000USD0001558370-25-010796
    Q2 2024Quarterly · 2024-06-30ProductUpstaza1,589,000USD0001558370-25-010796
    Q1 2024Quarterly · 2024-03-31ProductCollaboration And License Revenue0USD0001070081-25-000019
    Q1 2024Quarterly · 2024-03-31ProductManufacturing1,400,000USD0001070081-25-000019
    Q1 2024Quarterly · 2024-03-31ProductProduct177,604,000USD0001070081-25-000019
    Q1 2024Quarterly · 2024-03-31ProductRoyalty31,200,000USD0001070081-25-000019
    FY 2023Yearly · 2023-12-31ProductCollaboration And License Revenue0USD0001104659-26-017575
    FY 2023Yearly · 2023-12-31ProductCollaboration Revenue100,000,000USD0001104659-26-017575
    FY 2023Yearly · 2023-12-31ProductEmflaza255,087,000USD0001104659-26-017575
    FY 2023Yearly · 2023-12-31ProductManufacturing7,700,000USD0001104659-26-017575
    FY 2023Yearly · 2023-12-31ProductOther Products31,496,000USD0001104659-26-017575
    FY 2023Yearly · 2023-12-31ProductRoyalty168,900,000USD0001104659-26-017575
    FY 2023Yearly · 2023-12-31ProductTranslarna23,072,000USD0001104659-26-017575
    FY 2023Yearly · 2023-12-31ProductTranslarna1332,753,000USD0001104659-26-017575
    FY 2023Yearly · 2023-12-31ProductUpstaza And Kebilidi18,841,000USD0001104659-26-017575

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.