PSNL

MKT CAP:$540M

Personalis, Inc.

Market Cap

$540M

Healthcare·Medical - Diagnostics & Research·🇺🇸 United States·NASDAQ

Healthcare·Medical·🇺🇸·NASDAQ

Stock Price

$6.10-$1.75 (-22.29%)

Apr 24, 2026

Company Details

Personalis, Inc. operates as a cancer genomics company worldwide. The company provides sequencing and data analysis services to support the development of cancer therapies and large-scale genetic research programs. It offers NeXT Platform, ...

CEO

Christopher Hall

IPO Date

Jun 20, 2019

Website

www.personalis.com

Key Metrics TTM

Revenue

$70M

-17.7% YoY

Net Income

-$81M

EPS (Diluted)

-$0.91

Free Cash Flow

-$79M

Revenue / Share

$0.75

Gross Margin

22.7%

Operating Margin

-126.4%

Net Margin

-116.7%

FCF Margin

-114.1%

P/S

7.8x

P/E

—

Earnings Reports

Q1 2026

May 5, 2026

PENDING

FY 2025

Feb 26, 2026

$0-100.0%EPS -$0.91

Q4 2025

Feb 26, 2026

$17M+3.2%EPS -$0.26

Q3 2025

Nov 4, 2025

$14M-43.6%EPS -$0.24

Q2 2025

Aug 5, 2025

$17M-23.8%EPS -$0.23

Revenue & Profitability

Quarter	Revenue	Gross Profit	Operating Income
Q1 22	$15M	$4M	-$28M
Q2 22	$18M	$4M	-$28M
Q3 22	$15M	$2M	-$27M
Q4 22	$17M	$2M	-$32M
Q1 23	$19M	$5M	-$30M
Q2 23	$17M	$5M	-$25M
Q3 23	$18M	$3M	-$31M
Q4 23	$20M	$5M	-$24M
Q1 24	$20M	$5M	-$19M
Q2 24	$23M	$8M	-$17M
Q3 24	$26M	$9M	-$14M
Q4 24	$17M	$5M	-$18M
Q1 25	$21M	$7M	-$18M
Q2 25	$17M	$5M	-$22M
Q3 25	$14M	$2M	-$23M
Q4 25	$17M	$2M	-$25M

Valuation

Quarter	P/S	P/E
Q1 22	4.4x	—
Q2 22	2.3x	—
Q3 22	2.3x	—
Q4 22	1.7x	—
Q1 23	1.9x	—
Q2 23	1.3x	—
Q3 23	0.9x	—
Q4 23	1.5x	—
Q1 24	1.0x	—
Q2 24	0.9x	—
Q3 24	4.5x	—
Q4 24	5.1x	—
Q1 25	3.0x	—
Q2 25	7.1x	—
Q3 25	8.1x	—
Q4 25	10.1x	—

Operating Cash Flow

Quarter	Operating CF	Free CF
Q1 22	-$11M	-$20M
Q2 22	-$27M	-$38M
Q3 22	-$15M	-$36M
Q4 22	-$17M	-$26M
Q1 23	-$16M	-$20M
Q2 23	-$10M	-$13M
Q3 23	-$17M	-$18M
Q4 23	-$13M	-$17M
Q1 24	-$20M	-$21M
Q2 24	-$11M	-$11M
Q3 24	-$6M	-$6M
Q4 24	-$8M	-$9M
Q1 25	-$18M	-$20M
Q2 25	-$13M	-$13M
Q3 25	-$22M	-$23M
Q4 25	-$22M	-$22M

Capital Expenditures

Quarter	CapEx
Q1 22	$9M
Q2 22	$10M
Q3 22	$21M
Q4 22	$10M
Q1 23	$4M
Q2 23	$3M
Q3 23	$868.0K
Q4 23	$4M
Q1 24	$104.0K
Q2 24	$6.0K
Q3 24	$247.0K
Q4 24	$1M
Q1 25	$3M
Q2 25	$290.0K
Q3 25	$2M
Q4 25	$77.0K

CapEx

OpEx vs Revenue Growth (YoY)

Quarter	Revenue Growth	OpEx Growth
Q1 22	-27.1%	+30.5%
Q2 22	-15.8%	+26.0%
Q3 22	-33.3%	+5.4%
Q4 22	-19.1%	+19.3%
Q1 23	+23.9%	+11.8%
Q2 23	-8.4%	-8.8%
Q3 23	+22.8%	+16.4%
Q4 23	+17.7%	-10.6%
Q1 24	+3.5%	-21.1%
Q2 24	+35.2%	-6.1%
Q3 24	+40.9%	-18.2%
Q4 24	-14.6%	-20.0%
Q1 25	+5.5%	-0.3%
Q2 25	-23.8%	-1.2%
Q3 25	-43.6%	-5.7%
Q4 25	+3.2%	+22.1%

Stock-Based Compensation

Quarter	SBC ($)	% of Revenue
Q1 22	$5M	31.6%
Q2 22	$4M	24.2%
Q3 22	$4M	29.7%
Q4 22	$6M	34.6%
Q1 23	$4M	19.6%
Q2 23	$3M	20.9%
Q3 23	$3M	19.1%
Q4 23	$3M	17.2%
Q1 24	$3M	13.8%
Q2 24	$3M	11.7%
Q3 24	$3M	10.4%
Q4 24	$3M	15.9%
Q1 25	$2M	10.8%
Q2 25	$3M	16.5%
Q3 25	$2M	14.4%
Q4 25	$2M	13.2%

OpEx Breakdown

Quarter	R&D	SG&A
Q1 22	$17M	$15M
Q2 22	$16M	$16M
Q3 22	$15M	$15M
Q4 22	$17M	$18M
Q1 23	$17M	$14M
Q2 23	$18M	$12M
Q3 23	$17M	$12M
Q4 23	$14M	$12M
Q1 24	$13M	$12M
Q2 24	$13M	$12M
Q3 24	$12M	$11M
Q4 24	$11M	$11M
Q1 25	$13M	$12M
Q2 25	$12M	$14M
Q3 25	$12M	$13M
Q4 25	$13M	$14M

War Chest

Quarter	Cash	Short-term Investments	Total
Q1 22	$92M	$175M	$267M
Q2 22	$87M	$147M	$233M
Q3 22	$84M	$109M	$193M
Q4 22	$89M	$79M	$168M
Q1 23	$87M	$62M	$149M
Q2 23	$97M	$40M	$137M
Q3 23	$72M	$48M	$121M
Q4 23	$57M	$57M	$114M
Q1 24	$44M	$51M	$95M
Q2 24	$48M	$39M	$87M
Q3 24	$76M	$68M	$144M
Q4 24	$91M	$94M	$185M
Q1 25	$71M	$115M	$186M
Q2 25	$53M	$120M	$173M
Q3 25	$50M	$101M	$151M
Q4 25	$124M	$116M	$240M

Shares Outstanding

Quarter	Shares (Diluted)	QoQ Change	YoY Change
Q1 22	45M	+0.4%	+6.5%
Q2 22	46M	+1.4%	+3.8%
Q3 22	46M	+0.6%	+3.2%
Q4 22	46M	+0.7%	+3.2%
Q1 23	47M	+1.0%	+3.9%
Q2 23	48M	+2.0%	+4.5%
Q3 23	49M	+2.1%	+6.0%
Q4 23	49M	+1.5%	+6.8%
Q1 24	51M	+2.5%	+8.4%
Q2 24	52M	+3.4%	+9.9%
Q3 24	61M	+16.5%	+25.4%
Q4 24	73M	+19.4%	+47.4%
Q1 25	87M	+20.0%	+72.6%
Q2 25	89M	+1.2%	+68.9%
Q3 25	89M	+0.2%	+45.3%
Q4 25	92M	+4.0%	+26.6%

Shares Outstanding

Revenue Per Employee

Period	Revenue/Employee	Employees
Q1 22	$46.7K	326
Q2 22	$56.0K	326
Q3 22	$45.6K	326
Q4 22	$41.9K	399
Q1 23	$47.3K	399
Q2 23	$41.9K	399
Q3 23	$45.7K	399
Q4 23	$49.3K	399
Q1 24	$48.9K	399
Q2 24	$56.6K	399
Q3 24	$64.4K	399
Q4 24	$73.4K	229
Q1 25	$90.0K	229
Q2 25	$75.1K	229
Q3 25	$63.3K	229
Q4 25	$66.7K	260

Revenue / Employee