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    PALI

    PALISADE BIO, INC.

    Company overview

    Market capitalization
    $261.41M
    Employees
    14
    Latest publication
    2026-09-29
    About PALISADE BIO, INC.

    Palisade Bio, Inc., a clinical-stage biopharmaceutical company, engages in developing oral phosphodiesterase-4 inhibitor prodrugs designed for targeted delivery to the terminal ileum and colon in the United States. Its lead clinical product candidate includes PALI-2108, which is in phase 1b clinical trial to treat patients with inflammatory bowel disease, including ulcerative colitis and Fibrostenotic Crohn's disease. The company has a research collaboration and license agreement with Giiant Pharma, Inc. for the development, manufacture, and commercialization of its compounds; license agreement with the Regents of the University of California for sole purpose of maintaining the Newsoara Co-Development; and a co-development and distribution agreement with Newsoara Biopharma Co., Ltd. The company was founded in 2001 and is headquartered in Denver, Colorado.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Revenue500,000USD0USD0USD0USD0USD0USD4,000USD0USD
    Research Development7,400,000USD6,397,000USD6,173,000USD1,394,000USD1,675,000USD950,000USD2,084,000USD2,137,000USD
    Total Operating Expenses12,198,000USD10,748,000USD9,981,000USD2,922,000USD2,843,000USD2,310,000USD3,382,000USD3,593,000USD
    Net Income-10,574,000USD-9,600,000USD-8,899,000USD-2,868,000USD-2,784,000USD-2,230,000USD-3,344,000USD-3,487,000USD
    Selling General Administrative—4,351,000USD3,808,000USD1,528,000USD1,168,000USD1,360,000USD1,298,000USD1,456,000USD
    Operating Income—-10,748,000USD-9,981,000USD-2,922,000USD-2,843,000USD-2,310,000USD-3,382,000USD-3,593,000USD
    Interest Expense—1,000USD2,000USD5,000USD2,000USD1,000USD3,000USD6,000USD
    Net Interest Income—-1,000USD-2,000USD-5,000USD-2,000USD-1,000USD-3,000USD-6,000USD
    Income Before Tax—-9,600,000USD-8,899,000USD-2,868,000USD-2,784,000USD-2,230,000USD-3,344,000USD-3,487,000USD
    Net Income From Continuing Ops—-9,600,000USD-8,899,000USD-2,868,000USD-2,784,000USD-2,230,000USD-3,344,000USD-3,487,000USD
    Ebitda—-10,748,000USD-10,185,000USD-2,862,000USD-2,781,000USD-2,228,000USD-3,382,000USD-3,480,000USD
    Reconciled Depreciation—0USD0USD1,000USD1,000USD1,000USD0USD1,000USD
    Total Other Income Expense Net—1,148,000USD1,082,000USD54,000USD59,000USD80,000USD38,000USD106,000USD
    Ebit——-10,182,000USD-2,863,000USD-2,782,000USD-2,229,000USD-3,338,000USD-3,481,000USD
    Depreciation And Amortization——-3,000USD1,000USD1,000USD1,000USD-3,000USD1,000USD
    Cost Of Revenue————1,000USD1,000USD2,000USD1,000USD
    Gross Profit————-1,000USD-1,000USD2,000USD-1,000USD
    Source0001357459-26-000017PreliminaryLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Revenue0USD0USD250,000USD250,000USD0USD13,520USD15,394USD260,000USD
    Cost Of Revenue3,000USD3,000USD4,000USD167,000USD168,000USD146,000USD—-990,000USD
    Gross Profit-3,000USD-3,000USD250,000USD-167,000USD-168,000USD-146,000USD15,394USD1,250,000USD
    Research Development10,192,000USD9,063,000USD6,893,000USD6,547,000USD2,430,000USD3,099,000USD4,061,000USD3,960,000USD
    Selling General Administrative7,864,000USD5,796,000USD6,202,000USD8,764,000USD9,307,000USD6,198,000USD7,272,000USD3,566,000USD
    Total Operating Expenses18,056,000USD14,859,000USD13,320,000USD15,721,000USD41,854,000USD9,151,000USD8,647,000USD8,519,000USD
    Operating Income-18,056,000USD-14,859,000USD-13,070,000USD-15,721,000USD-41,854,000USD-9,297,000USD-8,632,000USD-8,259,000USD
    Interest Expense10,000USD12,000USD15,000USD13,000USD2,398,000USD235,000USD8,920USD7,698USD
    Net Interest Income-10,000USD-12,000USD-15,000USD-13,000USD-3,084,000USD-1,076,000USD——
    Income Before Tax-16,781,000USD-14,438,000USD-12,300,000USD-14,260,000USD-26,616,000USD-10,322,000USD-8,352,000USD-4,925,000USD
    Net Income-16,781,000USD-14,438,000USD-12,300,000USD-14,260,000USD-26,616,000USD-10,322,000USD-8,352,000USD-4,925,000USD
    Net Income From Continuing Ops-16,781,000USD-14,438,000USD-12,300,000USD-14,260,000USD-26,616,000USD-10,322,000USD——
    Ebit-16,771,000USD-14,426,000USD-12,285,000USD-14,247,000USD-24,218,000USD-10,087,000USD-8,342,859USD-4,916,803USD
    Ebitda-16,768,000USD-14,423,000USD-12,281,000USD-14,244,000USD-24,216,000USD-9,941,000USD-8,199,000USD-4,731,000USD
    Depreciation And Amortization3,000USD3,000USD4,000USD3,000USD2,000USD146,000USD143,859USD185,803USD
    Reconciled Depreciation3,000USD3,000USD4,000USD3,000USD2,000USD3,000USD——
    Total Other Income Expense Net1,275,000USD421,000USD770,000USD1,461,000USD15,238,000USD-1,025,000USD280,043USD3,335,000USD
    Selling And Marketing Expenses——4,000USD————807,462USD
    Income Tax Expense——16,000USD-1,461,000USD655,000USD248,000USD288,963USD3,343,000USD
    Net Income Applicable To Common Shares———-14,548,000USD-26,616,000USD-10,322,000USD-10,064,000USD-4,484,000USD
    Unclassified Operating Expenses————30,117,000USD—-2,686,000USD—
    Interest Income—————28,810USD557,950USD3,340,230USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets127,315,000USD133,315,000USD134,344,000USD6,973,000USD6,667,000USD8,190,000USD10,880,000USD9,336,000USD
    Cash And Equivalents125,172,000USD———————
    Total Current Assets127,260,000USD133,243,000USD134,221,000USD6,828,000USD6,447,000USD7,887,000USD10,494,000USD8,870,000USD
    Total Liabilities5,567,000USD———————
    Total Current Liabilities5,246,000USD5,620,000USD4,636,000USD3,478,000USD3,970,000USD2,777,000USD3,236,000USD2,681,000USD
    Total Stockholder Equity121,748,000USD127,362,000USD129,380,000USD3,212,000USD2,620,000USD5,331,000USD7,492,000USD6,608,000USD
    Total Equity Including Noncontrolling Interest121,748,000USD———————
    Short Long Term Debt71,000USD—71,000USD211,000USD314,000USD—79,000USD235,000USD
    Net Receivables500,000USD9,000USD264,000USD18,000USD6,000USD78,000USD24,000USD96,000USD
    Other Current Assets—606,000USD572,000USD1,583,000USD1,024,000USD579,000USD649,000USD830,000USD
    Total Liab—5,953,000USD4,964,000USD3,761,000USD4,047,000USD2,859,000USD3,388,000USD2,728,000USD
    Other Current Liab—2,924,000USD3,798,000USD1,841,000USD1,847,000USD1,777,000USD1,853,000USD1,958,000USD
    Common Stock—1,674,000USD1,594,000USD91,000USD48,000USD43,000USD27,000USD11,000USD
    Capital Stock—1,676,000USD1,596,000USD93,000USD50,000USD45,000USD29,000USD13,000USD
    Retained Earnings—-162,325,000USD-152,725,000USD-143,826,000USD-140,958,000USD-138,174,000USD-135,944,000USD-132,600,000USD
    Cash—132,628,000USD133,385,000USD5,227,000USD5,417,000USD7,230,000USD9,821,000USD8,040,000USD
    Cash And Short Term Investments—132,628,000USD133,385,000USD5,227,000USD5,417,000USD7,230,000USD9,821,000USD8,040,000USD
    Net Debt—-132,628,000USD-133,314,000USD-5,016,000USD-5,079,000USD-7,172,000USD-9,652,000USD-7,683,000USD
    Accounts Payable—2,696,000USD767,000USD1,426,000USD1,785,000USD942,000USD1,214,000USD366,000USD
    Common Stock Shares Outstanding—209,663,966shares55,669,821shares7,473,898shares4,797,196shares4,796,000shares8,540,000shares5,818,000shares
    Non Current Assets Total—72,000USD123,000USD145,000USD220,000USD303,000USD386,000USD466,000USD
    Non Current Liabilities Total—333,000USD328,000USD283,000USD77,000USD82,000USD152,000USD47,000USD
    Non Current Liabilities Other—271,000USD266,000USD283,000USD75,000USD80,000USD150,000USD47,000USD
    Non Currrent Assets Other—17,000USD68,000USD119,000USD197,000USD222,000USD273,000USD324,000USD
    Net Working Capital—127,623,000USD129,585,000USD3,350,000USD2,477,000USD5,110,000USD7,258,000USD6,189,000USD
    Unclassified Equity—286,337,000USD278,915,000USD146,854,000USD143,480,000USD143,417,000USD143,380,000USD139,184,000USD
    Short Term Debt——71,000USD211,000USD338,000USD58,000USD169,000USD357,000USD
    Short Long Term Debt Total——71,000USD211,000USD338,000USD58,000USD169,000USD357,000USD
    Property Plant Equipment Net——0USD0USD23,000USD55,000USD87,000USD116,000USD
    Property Plant Equipment Gross——0USD0USD23,000USD55,000USD87,000USD116,000USD
    Inventory———————-96,000USD
    Source0001357459-26-000017PreliminaryLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Assets134,344,000USD10,880,000USD14,052,000USD15,763,000USD12,512,000USD3,019,000USD6,583,889USD7,684,450USD
    Other Current Assets572,000USD649,000USD748,000USD912,000USD861,000USD167,000USD510,900USD363,288USD
    Total Liab4,964,000USD3,388,000USD2,739,000USD3,284,000USD5,147,000USD10,118,000USD1,457,896USD1,634,900USD
    Total Stockholder Equity129,380,000USD7,492,000USD11,313,000USD12,479,000USD7,365,000USD-7,099,000USD5,125,993USD6,049,550USD
    Other Current Liab3,798,000USD1,962,000USD1,609,000USD1,060,000USD779,000USD4,330,000USD260,351USD218,602USD
    Common Stock1,594,000USD27,000USD93,000USD30,000USD3,000USD28,000USD38,665USD182,051USD
    Capital Stock1,596,000USD29,000USD95,000USD32,000USD145,000USD28,000USD——
    Retained Earnings-152,725,000USD-135,944,000USD-121,506,000USD-109,190,000USD-94,642,000USD-68,026,000USD-221,975,544USD-213,623,893USD
    Cash133,385,000USD9,821,000USD12,432,000USD12,383,000USD10,495,000USD713,000USD5,114,917USD5,787,110USD
    Cash And Short Term Investments133,385,000USD9,821,000USD12,432,000USD12,383,000USD10,495,000USD729,000USD5,114,917USD5,787,110USD
    Total Current Assets134,221,000USD10,494,000USD13,328,000USD14,733,000USD11,506,000USD896,000USD5,646,881USD6,508,393USD
    Total Current Liabilities4,636,000USD3,236,000USD2,586,000USD3,012,000USD2,496,000USD8,082,000USD1,224,757USD1,051,166USD
    Net Debt-133,314,000USD-9,652,000USD-12,063,000USD-11,979,000USD-10,296,000USD708,000USD-4,826,374USD-749,110USD
    Short Term Debt71,000USD169,000USD279,000USD193,000USD199,000USD1,215,000USD140,000USD—
    Short Long Term Debt71,000USD79,000USD158,000USD88,000USD87,000USD1,047,000USD——
    Short Long Term Debt Total71,000USD169,000USD369,000USD404,000USD199,000USD1,421,000USD288,543USD5,038,000USD
    Net Receivables264,000USD24,000USD148,000USD1,438,000USD150,000USD59,000USD21,064USD357,995USD
    Accounts Payable767,000USD1,105,000USD698,000USD1,759,000USD1,518,000USD2,537,000USD824,406USD832,564USD
    Property Plant Equipment Net0USD87,000USD208,000USD310,000USD112,000USD280,000USD242,736USD90,311USD
    Property Plant Equipment Gross0USD87,000USD208,000USD310,000USD112,000USD10,776USD268,072USD90,311USD
    Common Stock Shares Outstanding55,669,821shares1,416,000shares456,014shares880,305shares12,463shares237,390shares237,390shares273,240shares
    Non Current Assets Total123,000USD386,000USD724,000USD1,030,000USD1,006,000USD2,123,000USD937,008USD1,176,057USD
    Non Current Liabilities Total328,000USD152,000USD153,000USD272,000USD2,651,000USD2,036,000USD233,138USD583,734USD
    Non Current Liabilities Other266,000USD150,000USD63,000USD61,000USD2,651,000USD1,830,000USD——
    Non Currrent Assets Other68,000USD273,000USD516,000USD694,000USD894,000USD1,843,000USD25,336USD23,965USD
    Net Working Capital129,585,000USD7,258,000USD10,742,000USD11,721,000USD9,878,000USD-7,186,000USD——
    Unclassified Equity278,915,000USD143,380,000USD132,631,000USD121,607,000USD101,859,000USD60,871,734USD227,069,058USD219,491,805USD
    Inventory—12,000USD—-1,438,000USD-150,000USD-2,227,552USD——
    Accumulated Other Comprehensive Income——0USD——-734USD-6,186USD-413USD
    Other Liab————2,651,000USD1,830,000USD—176,000USD
    Other Assets————26,000USD157,572USD26,000USD0USD
    Net Tangible Assets————7,363,000USD-16,602,000USD-8,332,000USD-45,198,000USD
    Unclassified Non Current Liabilities————-2,651,000USD-3,535,000USD——
    Intangible Assets—————147,130USD668,936USD763,543USD
    Deferred Long Term Liab—————1,817,000USD——
    Long Term Debt—————94,000USD——
    Short Term Investments—————16,000USD——
    Unclassified Current Liabilities—————-1,047,000USD——
    Current Deferred Revenue———————-4,503,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-9,600,000USD-8,899,000USD-2,868,000USD-2,784,000USD-2,230,000USD-3,344,000USD-3,487,000USD-4,080,000USD
    Depreciation0USD0USD1,000USD1,000USD1,000USD0USD1,000USD1,000USD
    Stock Based Compensation4,297,000USD3,727,000USD90,000USD69,000USD69,000USD77,000USD95,000USD362,000USD
    Other Non Cash Items4,302,000USD-84,000USD293,000USD98,000USD30,000USD145,000USD-84,000USD106,000USD
    Change In Working Capital1,408,000USD2,112,000USD-1,069,000USD799,000USD-203,000USD741,000USD342,000USD112,000USD
    Total Cash From Operating Activities-3,890,000USD-3,144,000USD-3,553,000USD-1,817,000USD-2,333,000USD-2,381,000USD-3,133,000USD-3,499,000USD
    Capital Expenditures0USD0USD0USD0USD0USD0USD0USD0USD
    Free Cash Flow-3,890,000USD-3,144,000USD-3,553,000USD-1,817,000USD-2,333,000USD-2,381,000USD-3,133,000USD-3,499,000USD
    Net Borrowings-71,000USD-140,000USD-100,000USD0USD-80,000USD-156,000USD-112,000USD—
    Total Cash From Financing Activities3,133,000USD131,331,000USD3,363,000USD4,000USD-258,000USD4,162,000USD-180,000USD3,576,000USD
    Issuance Of Capital Stock3,250,000USD128,219,000USD0USD0USD0USD4,435,000USD0USD4,000,000USD
    Change In Cash-757,000USD128,187,000USD-190,000USD-1,813,000USD-2,591,000USD1,781,001USD-3,313,000USD77,000USD
    Begin Period Cash Flow133,384,999USD5,253,000USD5,417,000USD7,256,000USD9,847,000USD8,039,999USD11,379,000USD11,276,000USD
    End Period Cash Flow132,627,999USD133,440,000USD5,227,000USD5,443,000USD7,256,000USD9,821,000USD8,066,000USD11,353,000USD
    Other Cashflows From Financing Activities3,133,000USD-49,999USD-445,000USD4,000USD-258,000USD8,318,000USD-68,000USD-424,000USD
    Unclassified Operating Cash Flow-4,297,000USD———————
    Unclassified Financing Cash Flow-3,179,000USD131,504,999USD3,908,000USD——-4,011,000USD—3,989,000USD
    Sale Purchase Of Stock—16,000USD—3,000USD—11,000USD—11,000USD
    Investments—————0USD0USD—
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Net Income-16,781,000USD-14,438,000USD-12,300,000USD-14,260,000USD-26,616,000USD-10,322,000USD-8,351,651USD-4,924,617USD
    Depreciation3,000USD3,000USD4,000USD3,000USD2,000USD3,000USD143,859USD185,803USD
    Stock Based Compensation3,955,000USD652,000USD624,000USD1,032,000USD1,891,000USD2,014,000USD3,325,000USD1,090,000USD
    Other Non Cash Items337,000USD199,000USD139,000USD-1,385,000USD14,706,000USD1,186,000USD743,827USD-2,288,936USD
    Change In Working Capital1,639,000USD1,391,000USD400,000USD1,250,000USD-4,756,000USD2,389,000USD208,285USD-336,881USD
    Total Cash From Operating Activities-10,847,000USD-12,193,000USD-11,133,000USD-13,360,000USD-14,773,000USD-4,768,000USD-7,255,680USD-7,692,419USD
    Capital Expenditures0USD0USD-4,000USD-10,000USD0USD-6,000USD-6,000USD-1,714USD
    Free Cash Flow-10,847,000USD-12,193,000USD-11,137,000USD-13,370,000USD-14,773,000USD-4,774,000USD-7,255,680USD-7,694,133USD
    Net Borrowings-320,000USD-426,000USD-391,000USD-790,000USD-183,000USD1,977,000USD-220,000USD1,357,000USD
    Total Cash From Financing Activities134,440,000USD9,582,000USD11,186,000USD15,258,000USD24,609,000USD1,890,000USD6,589,505USD1,814,233USD
    Sale Purchase Of Stock19,000USD11,000USD17,000USD—-99,000USD14,698,210USD6,553,080USD1,828,000USD
    Issuance Of Capital Stock128,219,000USD8,435,000USD9,419,000USD14,401,000USD25,109,000USD1,175,000USD——
    Change In Cash123,593,000USD-2,611,000USD49,000USD1,888,000USD9,782,000USD-2,884,000USD-672,193USD-887,830USD
    Begin Period Cash Flow9,847,000USD12,458,000USD12,409,000USD10,521,000USD739,000USD3,623,000USD5,787,110USD6,674,940USD
    End Period Cash Flow133,440,000USD9,847,000USD12,458,000USD12,409,000USD10,521,000USD739,000USD5,114,917USD5,787,110USD
    Other Cashflows From Financing Activities-495,000USD1,573,000USD2,158,000USD1,647,000USD19,583,000USD-87,000USD6,553,078USD207,000USD
    Unclassified Financing Cash Flow135,236,000USD8,424,000USD9,402,000USD—5,407,000USD-14,698,210USD-6,296,653USD-1,577,767USD
    Investments—0USD-4,000USD-10,000USD-54,000USD-6,000USD——
    Total Cashflows From Investing Activities——-4,000USD-10,000USD-54,000USD-6,000USD3,921,193USD4,998,286USD
    Change To Account Receivables————84,000USD-59,000USD272,993USD80,809USD
    Change To Inventory————-84,000USD-947,000USD15,741USD36,991USD
    Change To Liabilities————-2,395,000USD1,006,000USD836,000USD86,000USD
    Dividends Paid————-99,000USD———
    Other Cashflows From Investing Activities————-54,000USD——5,000,000USD
    Unclassified Operating Cash Flow——————-3,325,000USD-1,417,788USD
    Unclassified Investing Cash Flow——————3,927,193USD—
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    No revenue breakdown is currently published for this company.

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.