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    Nautilus Biotechnology, Inc.

    Company overview

    Market capitalization
    $141.25M
    Employees
    127
    Latest publication
    2026-09-29
    About Nautilus Biotechnology, Inc.

    Nautilus Biotechnology, Inc., a development stage life sciences company, engages in creating a platform technology for quantifying and unlocking the complexity of the proteome in the United States. The company develops Nautilus Voyager Platform, which includes an end-to-end solution comprising instruments, reagents, consumables, and software analysis. It also provides nautilus voyager instrument, a high-resolution optical imaging system with integrated fluidics and liquid handling sub-system to deposit protein libraries onto a flow cell and to process labeled multi-affinity reagent binding and imaging cycles rapidly to decode and quantify the proteins present in biological samples. In addition, the company offers single-molecule library preparation kits, flow cells, affinity reagents, and instrument run buffers to perform multi-cycle analysis runs. It has a research collaboration agreement Genentech, Buck Institute, Allen Institute, Cornell University and the Qatar Foundation, and Michael J. Fox Foundation. Nautilus Biotechnology, Inc. was founded in 2016 and is headquartered in Seattle, Washington.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ2 20242024-06-30 · USDQ2 20222022-06-30 · USD
    Total Revenue190,000USD0USD0USD0USD0USD0USD0USD0USD
    Cost Of Revenue15,000USD1,476,000USD1,588,000USD1,619,000USD1,633,000USD1,625,000USD1,597,000USD829,000USD
    Gross Profit175,000USD-1,476,000USD-1,588,000USD-1,619,000USD-1,633,000USD-1,625,000USD-1,597,000USD-829,000USD
    Research Development9,613,000USD9,373,000USD10,923,000USD9,605,000USD10,394,000USD11,536,000USD11,924,000USD8,575,000USD
    Selling General Administrative6,325,000USD6,417,000USD5,849,000USD5,867,000USD6,703,000USD7,308,000USD8,353,000USD6,616,000USD
    Total Operating Expenses15,938,000USD14,648,000USD13,836,000USD15,472,000USD17,097,000USD18,844,000USD19,192,000USD14,643,000USD
    Operating Income-15,763,000USD-16,123,999USD-15,424,000USD-15,472,000USD-17,097,000USD-18,844,000USD-20,789,000USD-15,472,000USD
    Total Other Income Expense Net1,294,000USD1,426,999USD1,643,000USD1,898,000USD2,064,000USD2,231,000USD2,779,000USD783,000USD
    Net Income-14,469,000USD-14,697,000USD-13,781,000USD-13,574,000USD-15,033,000USD-16,613,000USD-18,010,000USD-14,689,000USD
    Unclassified Operating Expenses—-1,142,000USD-2,936,000USD———-1,085,000USD—
    Interest Income—1,442,000USD1,654,000USD1,903,000USD2,080,000USD2,231,000USD2,798,000USD—
    Net Interest Income—1,442,000USD1,654,000USD1,903,000USD2,080,000USD2,231,000USD2,798,000USD—
    Income Before Tax—-14,697,000USD-13,781,000USD-13,574,000USD-15,033,000USD-16,613,000USD-18,010,000USD-14,689,000USD
    Net Income From Continuing Ops—-14,697,000USD-13,781,000USD-13,574,000USD-15,033,000USD-16,613,000USD-18,010,000USD-14,689,000USD
    Ebit—-14,697,000USD-13,781,000USD-13,574,000USD-15,033,000USD-16,613,000USD-18,010,000USD-14,689,000USD
    Ebitda—-13,221,000USD-12,193,000USD-11,955,000USD-13,400,000USD-14,988,000USD-16,413,000USD-13,860,000USD
    Depreciation And Amortization—1,476,000USD1,588,000USD1,619,000USD1,633,000USD1,625,000USD1,597,000USD829,000USD
    Reconciled Depreciation—1,476,000USD1,588,000USD1,619,000USD1,633,000USD1,625,000USD1,597,000USD829,000USD
    Interest Expense———————783,000USD
    Income Tax Expense———————-783,000USD
    Non Operating Income Net Other———————783,000USD
    Net Income Applicable To Common Shares———————-14,689,000USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20232023-12-31 · USDFY 20192019-12-31 · USD
    Total Revenue0USD0USD—
    Cost Of Revenue6,465,000USD5,705,000USD—
    Gross Profit-6,465,000USD-5,705,000USD—
    Research Development41,110,000USD47,251,000USD8,488,000USD
    Selling General Administrative25,727,000USD28,901,000USD1,622,000USD
    Unclassified Operating Expenses-6,465,000USD-5,705,000USD—
    Total Operating Expenses60,372,000USD70,447,000USD10,110,000USD
    Operating Income-66,837,000USD-76,152,000USD-10,110,000USD
    Interest Income7,868,000USD12,404,000USD—
    Net Interest Income7,868,000USD12,404,000USD—
    Income Before Tax-59,001,000USD-63,675,000USD-9,618,000USD
    Net Income-59,001,000USD-63,675,000USD-9,618,000USD
    Net Income From Continuing Ops-59,001,000USD-60,060,000USD—
    Ebit-59,001,000USD-63,675,000USD-10,110,000USD
    Ebitda-52,536,000USD-61,826,000USD-9,562,000USD
    Depreciation And Amortization6,465,000USD1,849,000USD548,000USD
    Reconciled Depreciation6,465,000USD5,036,000USD—
    Total Other Income Expense Net7,836,000USD12,477,000USD492,000USD
    Interest Expense——0USD
    Income Tax Expense——-171,312USD
    Net Income Applicable To Common Shares——-9,618,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets163,576,000USD177,779,000USD191,112,000USD200,915,000USD213,189,000USD227,690,000USD242,743,000USD259,704,000USD
    Cash And Equivalents13,166,000USD———————
    Total Current Assets87,626,000USD98,832,000USD105,963,000USD134,325,000USD150,725,000USD141,601,000USD132,826,000USD144,205,000USD
    Other Current Assets3,595,000USD2,963,000USD2,557,000USD2,898,000USD2,852,000USD2,791,000USD2,933,000USD3,596,000USD
    Other Non Current Assets1,177,000USD———————
    Total Liabilities32,464,000USD———————
    Total Current Liabilities8,639,000USD8,343,000USD7,952,000USD8,982,000USD8,137,000USD8,156,000USD7,632,000USD8,662,000USD
    Total Stockholder Equity131,112,000USD144,415,000USD156,973,000USD169,139,000USD181,094,000USD194,435,000USD208,730,000USD223,434,000USD
    Total Equity Including Noncontrolling Interest131,112,000USD———————
    Property Plant Equipment Net29,618,000USD30,266,000USD31,230,000USD28,351,000USD29,648,000USD30,886,000USD32,332,000USD33,701,000USD
    Accounts Payable1,095,000USD1,186,000USD943,000USD893,000USD974,000USD841,000USD987,000USD1,487,000USD
    Short Term Debt3,991,000USD3,852,000USD3,832,000USD4,209,000USD4,225,000USD4,242,000USD4,097,000USD3,959,000USD
    Common Stock13,000USD13,000USD13,000USD13,000USD13,000USD13,000USD13,000USD13,000USD
    Retained Earnings-361,186,000USD-346,717,000USD-332,020,000USD-318,239,000USD-304,665,000USD-289,632,000USD-273,019,000USD-255,425,000USD
    Accumulated Other Comprehensive Income-331,000USD-91,000USD243,000USD200,000USD77,000USD189,000USD57,000USD731,000USD
    Total Liab—33,364,000USD34,139,000USD31,776,000USD32,095,000USD33,255,000USD34,013,000USD36,270,000USD
    Other Current Liab—3,305,000USD3,177,000USD3,880,000USD2,938,000USD3,073,000USD2,548,000USD3,216,000USD
    Capital Stock—13,000USD13,000USD13,000USD13,000USD13,000USD13,000USD13,000USD
    Cash—14,626,000USD12,388,000USD23,875,000USD34,457,000USD33,238,000USD27,646,000USD4,409,000USD
    Cash And Short Term Investments—95,869,000USD103,406,000USD131,427,000USD147,873,000USD138,810,000USD129,893,000USD140,609,000USD
    Net Debt—14,247,000USD17,631,000USD3,128,000USD-6,274,000USD-3,897,000USD2,832,000USD27,158,000USD
    Short Long Term Debt Total—28,873,000USD30,019,000USD27,003,000USD28,183,000USD29,341,000USD30,478,000USD31,567,000USD
    Long Term Investments—47,505,000USD52,739,000USD37,059,000USD31,636,000USD54,023,000USD76,405,000USD80,618,000USD
    Short Term Investments—81,243,000USD91,018,000USD107,552,000USD113,416,000USD105,572,000USD102,247,000USD136,200,000USD
    Property Plant Equipment Gross—38,726,000USD39,351,000USD36,089,000USD37,091,000USD37,886,000USD38,866,000USD39,814,000USD
    Common Stock Shares Outstanding—126,634,782shares126,256,583shares126,305,122shares126,204,632shares126,144,240shares125,796,000shares125,452,000shares
    Non Current Assets Total—78,947,000USD85,149,000USD66,590,000USD62,464,000USD86,089,000USD109,917,000USD115,499,000USD
    Non Current Liabilities Total—25,021,000USD26,187,000USD22,794,000USD23,958,000USD25,099,000USD26,381,000USD27,608,000USD
    Non Currrent Assets Other—1,176,000USD1,180,000USD1,180,000USD1,180,000USD1,180,000USD1,180,000USD1,180,000USD
    Net Working Capital—90,489,000USD98,011,000USD125,343,000USD142,588,000USD133,445,000USD125,194,000USD135,543,000USD
    Unclassified Non Current Liabilities—25,021,000USD26,187,000USD22,794,000USD23,958,000USD25,099,000USD26,381,000USD27,608,000USD
    Unclassified Equity—491,197,000USD488,724,000USD487,152,000USD485,656,000USD483,852,000USD481,666,000USD478,102,000USD
    Current Deferred Revenue———————-1,847,000USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USD
    Total Assets191,112,000USD242,743,000USD305,565,000USD350,052,000USD398,450,000USD85,011,000USD18,542,000USD
    Other Current Assets2,557,000USD2,933,000USD3,419,000USD2,738,000USD3,493,000USD917,000USD305,000USD
    Total Liab34,139,000USD34,013,000USD40,212,000USD35,128,000USD34,874,000USD114,732,000USD490,000USD
    Total Stockholder Equity156,973,000USD208,730,000USD265,353,000USD314,924,000USD363,576,000USD-29,721,000USD18,052,000USD
    Other Current Liab3,177,000USD2,548,000USD3,945,000USD3,528,000USD3,119,000USD1,069,000USD201,000USD
    Common Stock13,000USD13,000USD13,000USD12,000USD12,000USD1,000USD1,000USD
    Capital Stock13,000USD13,000USD13,000USD12,000USD12,000USD1,000USD—
    Retained Earnings-332,020,000USD-273,019,000USD-202,239,000USD-138,564,000USD-80,640,000USD-30,325,000USD-14,706,000USD
    Cash12,388,000USD27,646,000USD19,397,000USD114,523,000USD185,619,000USD36,607,000USD595,000USD
    Cash And Short Term Investments103,406,000USD129,893,000USD173,418,000USD184,471,000USD345,729,000USD76,742,000USD16,659,000USD
    Total Current Assets105,963,000USD132,826,000USD176,837,000USD187,209,000USD349,222,000USD77,659,000USD16,964,000USD
    Total Current Liabilities7,952,000USD7,632,000USD9,122,000USD6,791,000USD5,812,000USD3,018,000USD490,000USD
    Net Debt17,631,000USD2,832,000USD15,231,000USD-84,195,000USD-155,587,000USD-31,832,000USD274,405,000USD
    Short Term Debt3,832,000USD4,097,000USD3,538,000USD1,991,000USD970,000USD1,479,000USD—
    Short Long Term Debt Total30,019,000USD30,478,000USD34,628,000USD30,328,000USD30,032,000USD4,775,000USD275,000,000USD
    Long Term Investments52,739,000USD76,405,000USD90,647,000USD129,169,000USD16,371,000USD0USD—
    Short Term Investments91,018,000USD102,247,000USD154,021,000USD69,948,000USD160,110,000USD40,135,000USD16,064,000USD
    Accounts Payable943,000USD987,000USD1,639,000USD1,272,000USD1,723,000USD470,000USD289,000USD
    Property Plant Equipment Net31,230,000USD32,332,000USD36,901,000USD32,566,000USD31,860,000USD6,213,000USD1,119,000USD
    Property Plant Equipment Gross39,351,000USD38,866,000USD41,535,000USD3,700,000USD2,483,000USD7,498,000USD—
    Accumulated Other Comprehensive Income243,000USD57,000USD-255,000USD-1,854,000USD-184,000USD3,000USD7,000USD
    Common Stock Shares Outstanding126,256,583shares125,427,000shares124,919,000shares124,589,000shares84,464,000shares33,070,000shares6,066,928shares
    Non Current Assets Total85,149,000USD109,917,000USD128,728,000USD162,843,000USD49,228,000USD7,352,000USD1,578,000USD
    Non Current Liabilities Total26,187,000USD26,381,000USD31,090,000USD28,337,000USD29,062,000USD111,714,000USD275,000,000USD
    Non Currrent Assets Other1,180,000USD1,180,000USD1,180,000USD1,108,000USD997,000USD1,139,000USD459,000USD
    Net Working Capital98,011,000USD125,194,000USD167,715,000USD180,418,000USD343,410,000USD74,641,000USD—
    Unclassified Non Current Liabilities26,187,000USD26,381,000USD31,090,000USD——106,269,500USD275,000,000USD
    Unclassified Equity488,724,000USD481,666,000USD467,821,000USD455,318,000USD444,376,000USD—32,750,000USD
    Current Deferred Revenue——-948,000USD—2,731,000USD936,000USD—
    Other Assets———1,108,000USD997,000USD0USD459USD
    Non Current Liabilities Other———28,337,000USD29,062,000USD5,232,500USD—
    Net Tangible Assets———314,924,000USD363,576,000USD-29,721,000USD-14,509,000USD
    Unclassified Current Liabilities————-2,731,000USD——
    Deferred Long Term Liab—————212,000USD—
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-14,697,000USD-13,781,000USD-13,574,000USD-15,033,000USD-16,613,000USD-17,594,000USD-16,446,000USD-18,010,000USD
    Depreciation1,476,000USD1,588,000USD1,619,000USD1,633,000USD1,625,000USD1,553,000USD1,612,000USD1,597,000USD
    Stock Based Compensation1,362,000USD1,471,000USD1,496,000USD1,709,000USD2,168,000USD3,124,000USD3,184,000USD3,279,000USD
    Other Non Cash Items-68,000USD-134,000USD-306,000USD-439,000USD-541,000USD216,000USD-723,000USD-702,000USD
    Change In Working Capital-1,173,000USD-1,519,000USD-269,000USD-1,220,000USD-576,000USD-1,608,000USD-740,000USD-1,621,000USD
    Total Cash From Operating Activities-13,100,000USD-12,375,000USD-11,034,000USD-13,350,000USD-13,937,000USD-14,309,000USD-13,113,000USD-15,457,000USD
    Capital Expenditures-510,000USD-244,000USD-418,000USD-396,000USD-219,000USD-254,000USD-709,000USD-512,000USD
    Free Cash Flow-13,610,000USD-12,619,000USD-11,452,000USD-13,746,000USD-14,156,000USD-14,563,000USD-13,822,000USD-15,969,000USD
    Investments14,743,000USD1,031,000USD452,000USD14,474,000USD19,511,000USD37,106,000USD-7,503,000USD14,294,000USD
    Total Cashflows From Investing Activities14,233,000USD787,000USD452,000USD14,474,000USD19,511,000USD37,106,000USD-7,503,000USD14,294,000USD
    Total Cash From Financing Activities1,105,000USD101,000USD0USD95,000USD18,000USD440,000USD140,000USD319,000USD
    Change In Cash2,238,000USD-11,487,000USD-10,582,000USD1,219,000USD5,592,000USD23,237,000USD-20,476,000USD-844,000USD
    Begin Period Cash Flow13,390,000USD24,877,000USD35,459,000USD34,240,000USD28,648,000USD5,411,000USD24,885,000USD25,729,000USD
    End Period Cash Flow15,628,000USD13,390,000USD24,877,000USD35,459,000USD34,240,000USD28,648,000USD4,409,000USD24,885,000USD
    Sale Purchase Of Stock—-18,000USD87,000USD87,000USD——289,000USD—
    Other Cashflows From Investing Activities—-11,128,000USD74,241,000USD19,248,000USD26,630,000USD-760,000USD—14,806,000USD
    Other Cashflows From Financing Activities—101,000USD—8,000USD18,000USD440,000USD140,000USD319,000USD
    Unclassified Investing Cash Flow—11,128,000USD-73,823,000USD-18,852,000USD-26,411,000USD1,014,000USD—-14,294,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Net Income-59,001,000USD-70,780,000USD-63,675,000USD-57,924,000USD-50,315,000USD-15,619,000USD-9,618,000USD626,600,000USD
    Depreciation6,465,000USD6,353,000USD5,705,000USD3,416,000USD2,842,000USD2,346,000USD548,000USD—
    Stock Based Compensation6,844,000USD12,701,000USD12,137,000USD10,380,000USD7,934,000USD369,000USD110,000USD—
    Other Non Cash Items-1,420,000USD-1,960,000USD-2,659,000USD-890,000USD320,000USD295,000USD-157,000USD-866,225,272USD
    Change In Working Capital-3,584,000USD-5,459,000USD-3,219,000USD-788,000USD-22,000USD-1,387,000USD-545,000USD1,327,272USD
    Total Cash From Operating Activities-50,696,000USD-59,145,000USD-51,711,000USD-45,806,000USD-39,241,000USD-13,996,000USD-9,662,000USD-238,298,000USD
    Capital Expenditures-1,277,000USD-2,122,000USD-2,442,000USD-2,324,000USD-2,269,000USD-921,000USD-926,000USD0USD
    Free Cash Flow-51,973,000USD-61,267,000USD-54,153,000USD-48,130,000USD-41,510,000USD-14,917,000USD-10,588,000USD-238,298,000USD
    Investments36,501,000USD66,250,000USD-66,730,000USD-25,740,000USD-136,695,000USD-24,358,000USD4,976,000USD—
    Total Cashflows From Investing Activities35,224,000USD66,250,000USD-43,735,000USD-25,740,000USD-138,964,000USD-25,279,000USD4,050,000USD1,198,306USD
    Total Cash From Financing Activities214,000USD1,144,000USD368,000USD562,000USD327,447,000USD75,899,000USD36,000USD145,186,604,000USD
    Sale Purchase Of Stock156,000USD524,000USD264,000USD232,000USD-7,962,000USD154,490,000USD-874,326USD-1,198,306USD
    Change In Cash-15,258,000USD8,249,000USD-95,078,000USD-70,984,000USD149,242,000USD36,624,000USD595,000USD1,198,306USD
    Begin Period Cash Flow28,648,000USD20,399,000USD115,477,000USD186,461,000USD37,219,000USD595,000USD1,198,306USD—
    End Period Cash Flow13,390,000USD28,648,000USD20,399,000USD115,477,000USD186,461,000USD37,219,000USD595,000USD1,198,306USD
    Other Cashflows From Investing Activities108,991,000USD-760,000USD—163,175,000USD-136,695USD-24,358USD4,976,000USD1,198,306USD
    Other Cashflows From Financing Activities214,000USD1,144,000USD368,000USD562,000USD335,409,000USD75,899,000USD36,000USD145,186,604,000USD
    Unclassified Investing Cash Flow-108,991,000USD2,882,000USD25,437,000USD-160,851,000USD——-4,976,000USD—
    Change To Liabilities———-152,000USD3,516,000USD123,000USD66,000USD—
    Cash And Cash Equivalents Changes———-70,984,000USD149,242,000USD———
    Issuance Of Capital Stock————0USD75,857,000USD——
    Dividends Paid—————-52,952USD——
    Unclassified Financing Cash Flow—————-154,437,048USD——
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    No revenue breakdown is currently published for this company.

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.