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    MNPR

    Monopar Therapeutics

    Company overview

    Market capitalization
    $561.94M
    Employees
    22
    Latest publication
    2026-09-29
    About Monopar Therapeutics

    Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. The company develops ALXN1840, a late-stage, investigational once-daily and oral medicine; MNPR-101, a proprietary humanized monoclonal antibody that is conjugated with different radioisotopes for the treatment of advanced solid tumors expressing urokinase plasminogen activator receptor; and MNPR-101-Zr, which is in phase 1 imaging and dosimetry clinical trial, a radiopharmaceutical imaging agent comprised of MNPR-101 conjugated to zirconium-89. It develops MNPR-101-Lu, a Phase1a stage radiotherapeutic comprised of MNPR-101 conjugated to actinium-225. The company has collaborations NorthStar to develop radio-immuno-therapeutics targeting severe COVID-19; Excel Diagnostics and Nuclear Oncology Center, for the investigational imaging agent MNPR-101-Zr and investigational therapeutic agent MNPR-101-Lu; license agreement with Alexion to develop and commercialize ALXN1840, a drug candidate for Wilson disease. The company was founded in 2014 and is headquartered in Wilmette, Illinois.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Total Revenue0USD0USD0USD0USD0USD0USD0USD0USD
    Research Development3,487,247USD3,941,101USD2,589,749USD1,730,000USD1,643,375USD9,924,620USD984,278USD1,130,978USD
    Selling General Administrative1,738,006,000USD2,214,127USD1,503,326USD1,504,295USD1,578,442USD1,150,024USD590,624,000USD657,806USD
    Unclassified Operating Expenses-1,736,267,994USD—————-590,033,376USD—
    Total Operating Expenses5,225,253USD6,155,228USD4,093,074USD3,234,295USD3,221,817USD11,074,644USD1,574,902USD1,788,784USD
    Operating Income-5,225,253USD-6,155,228USD-4,093,074USD-3,234,295USD-3,221,817USD-11,074,644USD-1,574,902USD-1,788,784USD
    Interest Income1,332,203USD954,434USD655,473USD780,769USD596,845USD149,036USD99,344USD73,475USD
    Net Interest Income1,332,203USD954,434USD655,473USD780,769USD596,845USD149,036USD99,344USD73,475USD
    Income Before Tax-3,893,050USD-5,200,795USD-3,437,601USD-2,453,526USD-2,624,972USD-10,925,608USD-1,304,276USD-1,715,309USD
    Net Income-3,893,050USD-5,200,795USD-3,437,601USD-2,453,526USD-2,624,972USD-10,925,608USD-1,304,276USD-1,715,309USD
    Net Income From Continuing Ops-3,893,050USD-5,200,795USD-3,437,601USD-2,453,526USD-2,624,972USD-10,925,608USD-1,304,276USD-1,715,309USD
    Ebitda-5,225,253USD-6,155,228USD-4,093,075USD-2,453,526USD-3,221,817USD-10,925,608USD-1,304,278USD-1,788,784USD
    Total Other Income Expense Net1,332,203USD954,433USD655,473USD780,769USD596,845USD149,036USD270,626USD73,475USD
    Ebit———-3,234,295USD-6,444,000USD-21,574,000USD-2,723,000USD-3,151,000USD
    Depreciation And Amortization————3,222,000USD11,075,000USD1,575,000USD1,789,000USD
    Income Tax Expense———————-1,789,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Revenue0USD0USD0USD0USD0USD122,400USD0USD0USD
    Research Development9,904,225,000USD13,005,986USD5,600,193USD7,591,601USD6,493,208USD4,065,199USD1,968,518USD1,774,454USD
    Selling General Administrative6,800,190,000USD3,155,735USD3,231,042USD2,945,276USD2,634,040USD2,443,676USD2,355,243USD1,628,308USD
    Unclassified Operating Expenses-16,687,710,585USD———————
    Total Operating Expenses16,704,415USD16,161,721USD8,831,235USD10,536,877USD9,127,248USD6,508,875USD4,323,761USD3,402,762USD
    Operating Income-16,704,415USD-16,161,721USD-8,831,235USD-10,536,877USD-9,127,248USD-6,508,875USD-4,323,761USD-3,402,762USD
    Interest Income2,987,521USD404,020USD343,626USD21,239USD24,024USD81,902USD98,887USD103,215USD
    Net Interest Income2,987,521USD404,020USD343,626USD21,239USD24,024USD81,902USD98,887USD103,215USD
    Income Before Tax-13,716,894USD-15,586,419USD-8,402,196USD-10,515,638USD-9,103,224USD-6,304,573USD-4,224,874USD-3,299,547USD
    Net Income-13,716,894USD-15,586,419USD-8,402,196USD-10,494,399USD-9,079,200USD-6,304,573USD-4,125,987USD-3,227,932USD
    Net Income From Continuing Ops-13,716,894USD-15,586,419USD-9,484,619USD-10,515,638USD-9,103,224USD-6,304,573USD-4,224,874USD-3,227,932USD
    Ebitda-16,704,415USD-16,161,721USD-8,831,235USD-10,515,638USD-9,079,200USD-6,304,573USD-4,323,761USD-3,196,332USD
    Total Other Income Expense Net2,987,521USD575,302USD429,039USD21,239USD24,024USD204,302USD98,887USD103,215USD
    Ebit—-31,748,000USD-8,401,961USD-10,536,877USD-9,127,248USD-13,140,000USD-4,323,761USD-3,402,762USD
    Depreciation And Amortization—16,162,000USD8,831,000USD21,239USD48,048USD6,508,875USD4,324USD206,430USD
    Income Tax Expense——-8,831USD-21,239USD-24,024USD-81,902USD-98,887USD-71,615USD
    Interest Expense———21,239USD24,024USD81,902USD98,887USD103,215USD
    Net Income Applicable To Common Shares————-9,103,224USD-6,304,573USD-4,224,874USD-3,227,932USD
    Gross Profit—————122,400USD——
    Tax Provision———————-71,615USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets134,978,829USD137,983,725USD140,717,709USD144,197,000USD53,865,873USD55,085,318USD60,291,071USD6,069,654USD
    Cash And Equivalents52,757,766USD———————
    Total Current Assets134,763,709USD137,743,843USD140,462,788USD144,090,000USD53,747,703USD55,076,216USD60,291,071USD6,069,654USD
    Other Current Assets464,727USD250,903USD63,745USD415,000USD497,294USD523,556USD78,869USD49,570USD
    Total Liabilities4,123,859USD———————
    Total Current Liabilities4,016,031USD2,457,748USD2,735,236USD2,568,549USD1,583,613USD1,491,960USD5,254,300USD1,122,867USD
    Total Stockholder Equity130,854,970USD135,394,412USD137,827,553USD141,557,000USD52,201,894USD53,593,358USD55,036,771USD4,946,787USD
    Total Equity Including Noncontrolling Interest130,854,970USD———————
    Property Plant Equipment Net215,120USD239,882USD254,921USD106,666USD118,170USD9,102USD0USD0USD
    Accounts Payable4,016,031USD2,457,748USD2,735,236USD2,537,194USD1,583,613USD1,491,960USD2,254,300USD1,122,867USD
    Short Term Debt97,834USD——31,355USD————
    Common Stock6,712USD6,699USD6,692USD6,663USD6,127USD6,115USD6,103USD3,525USD
    Retained Earnings-98,715,880USD-93,402,580USD-89,509,530USD-84,308,735USD-80,871,134USD-78,417,608USD-75,792,636USD-64,867,028USD
    Accumulated Other Comprehensive Income91,317USD98,521USD131,389USD11,698USD77,577USD-21,784USD35,992USD-10,991USD
    Total Liab—2,589,313USD2,890,156USD2,640,000USD1,663,979USD1,491,960USD5,254,300USD1,122,867USD
    Other Current Liab—2,455,290,252USD2,732,500,764USD2,568,549,000USD1,583,613,000USD1,491,960,000USD3,000,000USD1,122,867USD
    Capital Stock—6,699USD6,692USD6,663USD6,127USD6,115USD6,103USD3,525USD
    Cash—52,544,263USD61,833,552USD127,677,360USD39,501,936USD39,711,409USD45,816,289USD6,020,084USD
    Cash And Short Term Investments—137,492,940USD140,399,043USD143,675,787USD53,250,409USD54,552,660USD60,212,202USD6,020,084USD
    Net Debt—-52,412,698USD-61,678,632USD-127,574,764USD-39,421,570USD-39,711,409USD-45,816,289USD-6,020,084USD
    Short Long Term Debt Total—131,565USD154,920USD102,236USD80,366USD———
    Short Term Investments—84,948,677USD78,565,491USD15,998,427USD13,748,473USD14,841,251USD14,395,913USD6,014,063,916USD
    Property Plant Equipment Gross—239,882USD254,921USD106,666USD118,170USD9,102USD0USD0USD
    Common Stock Shares Outstanding—8,535,000shares6,692,140shares7,123,849shares6,998,082shares6,987,000shares11,483,500shares11,483,500shares
    Non Current Assets Total—239,882USD254,921USD107,000USD118,170USD9,102USD0USD-6,063,584,346USD
    Non Current Liabilities Total—131,565USD154,920USD71,451USD80,366USD0USD0USD0USD
    Net Working Capital—135,286,095USD137,727,552USD141,522,063USD52,164,090USD53,584,256USD55,036,771USD4,946,787USD
    Unclassified Current Liabilities—-2,455,290,252USD-2,732,500,764USD-2,568,549,000USD-1,583,613,000USD-1,491,960,000USD—-1,122,867USD
    Unclassified Equity—228,685,073USD227,192,310USD225,840,711USD132,983,197USD132,020,520USD130,781,209USD69,817,756USD
    Non Currrent Assets Other———334USD————
    Unclassified Current Assets———————-6,014,063,916USD
    Unclassified Non Current Assets———————-6,063,584,346USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Assets140,717,709USD60,291,071USD7,345,159USD13,226,954USD20,521,614USD16,868,657USD13,352,021USD7,317,955USD
    Other Current Assets63,745USD78,869USD66,433USD45,982USD217,745USD62,690USD15,711USD425,183USD
    Total Liab2,890,156USD5,254,300USD1,757,393USD3,137,302USD1,580,543USD1,176,666USD724,165USD399,551USD
    Total Stockholder Equity137,827,553USD55,036,771USD5,587,766USD10,089,652USD18,941,071USD15,691,991USD12,627,856USD6,918,404USD
    Other Current Liab2,732,500,764USD3,000,000USD1,757,393,000USD-48,582USD1,580,543USD1,176,666USD724,165USD399,551USD
    Common Stock6,692USD6,103USD14,905USD12,947USD12,598USD11,453USD10,587USD9,291USD
    Capital Stock6,692USD6,103USD14,905USD12,947USD12,598USD11,453USD10,587USD9,291USD
    Retained Earnings-89,509,530USD-75,792,636USD-60,206,217USD-51,804,021USD-41,288,383USD-32,185,159USD-25,880,586USD-21,655,712USD
    Cash61,833,552USD45,816,289USD7,266,080USD8,186,194USD20,303,869USD16,737,109USD13,213,929USD6,892,772USD
    Cash And Short Term Investments140,399,043USD60,212,202USD7,266,080USD13,119,744USD20,303,869USD16,737,109USD13,213,929USD6,892,772USD
    Total Current Assets140,462,788USD60,291,071USD7,332,513USD13,165,726USD20,521,614USD16,799,799USD13,229,640USD7,317,955USD
    Total Current Liabilities2,735,236USD5,254,300USD1,757,393USD3,128,894USD1,580,543USD1,176,666USD724,165USD399,551USD
    Net Debt-61,678,632USD-45,816,289USD-7,266,080USD-8,177,786USD-20,303,869USD-16,737,109USD-13,213,929USD-6,892,772USD
    Short Long Term Debt Total154,920USD——8,408USD————
    Short Term Investments78,565,491USD14,395,913USD0USD4,933,550USD0USD———
    Accounts Payable2,735,236USD2,254,300USD1,757,393USD3,128,894USD1,580,543USD1,176,666USD724,165USD399,551USD
    Property Plant Equipment Net254,921USD0USD12,646USD61,228USD0USD———
    Property Plant Equipment Gross254,921USD0USD12,646USD61,228USD0USD———
    Accumulated Other Comprehensive Income131,389USD35,992USD-14,132USD8,942USD-3,160USD-7,873USD-10,970USD-2,396USD
    Common Stock Shares Outstanding7,411,000shares11,483,500shares14,511,000shares12,718,000shares12,472,000shares10,958,000shares10,588,000shares10,421,000shares
    Non Current Assets Total254,921USD60,230,779,929USD12,646USD61,228USD0USD68,858USD122,381USD410,667USD
    Non Current Liabilities Total154,920USD0USD0USD8,408USD1,580,543USD1,176,666USD724,165USD0USD
    Net Working Capital137,727,552USD55,036,771USD5,575,120USD10,036,832USD18,941,071USD15,623,133USD12,505,475USD6,918,404USD
    Unclassified Current Liabilities-2,732,500,764USD—-1,757,393,000USD—-1,580,543USD-1,176,666USD——
    Unclassified Equity227,192,310USD130,781,209USD65,778,305USD61,858,837USD60,207,418USD47,862,117USD38,498,238USD28,557,930USD
    Unclassified Non Current Assets—60,230,779,929USD——————
    Non Currrent Assets Other——0USD0USD—68,858USD122,381USD410,667USD
    Other Assets———0USD—68,858USD122,381USD-410,667USD
    Short Term Debt———48,582USD————
    Net Tangible Assets————18,941,071USD15,691,991USD12,627,856USD6,918,404USD
    Unclassified Non Current Liabilities————1,580,543USD1,176,666USD——
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-3,893,050USD-5,200,795USD-3,437,601USD-2,453,526USD-2,624,972USD-10,925,608USD-1,304,276USD-1,715,309USD
    Stock Based Compensation1,692,980USD1,104,104USD1,099,210USD1,279,546USD1,355,017USD278,612USD199,121USD334,390USD
    Other Non Cash Items893,346USD387,640USD1,099,210USD1,279,546USD1,355,017USD4,552,258USD28,693USD334,390USD
    Change In Working Capital-474,202USD1,443,083USD247,859USD96,609USD-4,393,361USD4,096,320USD2,962USD-295,879USD
    Total Cash From Operating Activities-3,473,906USD-3,370,072USD-2,090,532USD-1,077,371USD-5,663,316USD-1,998,418USD-1,073,500USD-1,676,798USD
    Capital Expenditures-4USD0USD-2USD-1USD-4USD0USD-2USD-2USD
    Free Cash Flow-3,473,910USD-3,370,070USD-2,090,530USD-1,077,370USD-5,663,320USD-1,998,418USD-1,073,500USD-1,676,800USD
    Investments-5,583,552USD-62,188,553USD-2,126,027USD1,187,294USD-325,828USD-14,338,403USD985,730USD-2,423USD
    Total Cashflows From Investing Activities-5,583,552USD-62,188,553USD-2,126,027USD1,187,294USD-325,828USD-14,338,403USD985,730USD-2,423USD
    Total Cash From Financing Activities-200,203USD-384,680USD92,391,609USD-316,845USD-115,682USD56,136,829USD-16,534USD-9,919USD
    Change In Cash-9,289,289USD-65,843,808USD88,175,424USD-209,473USD-6,104,880USD39,796,205USD-99,847USD-1,687,648USD
    Begin Period Cash Flow61,833,552USD127,677,360USD39,501,936USD39,711,409USD45,816,289USD6,020,084USD6,119,931USD7,807,579USD
    End Period Cash Flow52,544,263USD61,833,552USD127,677,360USD39,501,936USD39,711,409USD45,816,289USD6,020,084USD6,119,931USD
    Other Cashflows From Financing Activities-200,203USD-298,094USD-381,563USD-321,555USD-131,129USD-66,946USD-16,517USD-10,002USD
    Unclassified Operating Cash Flow-1,692,980USD-1,104,104USD-1,099,210USD-1,279,546USD-1,355,017USD———
    Sale Purchase Of Stock—0USD-34,999,957USD———-16,534USD-10USD
    Issuance Of Capital Stock—-631,386USD127,772,915USD0USD0USD56,203,775USD0USD-1USD
    Unclassified Financing Cash Flow——127,773,129USD—————
    Other Cashflows From Investing Activities——————985,730USD-2USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Net Income-13,716,894USD-15,586,419USD-8,402,196USD-10,515,638USD-9,103,224USD-6,304,573USD-4,224,874USD-3,227,932USD
    Depreciation-716,464,000USD———————
    Stock Based Compensation4,837,877,000USD1,140,785USD1,897,849USD1,641,263USD1,468,054USD1,320,890USD1,011,170USD529,332USD
    Other Non Cash Items4,121,413USD4,552,258USD1,895,951USD162,964USD1,064,087USD-122,400USD767,636USD441,648USD
    Change In Working Capital-2,605,810USD3,489,237USD-1,353,946USD1,645,816USD317,769USD443,809USD196,024USD-188,157USD
    Total Cash From Operating Activities-12,201,291USD-6,404,139USD-7,858,293USD-7,228,559USD-7,317,401USD-4,662,274USD-3,017,680USD-2,886,757USD
    Capital Expenditures0USD0USD-3USD0USD0USD-4USD0USD0USD
    Free Cash Flow-12,201,290USD-6,404,139USD-7,858,293USD-7,228,559USD-7,317,401USD-4,662,274USD-3,017,680USD-2,886,757USD
    Investments-63,453,114USD-14,338,403USD-2,961,198USD-4,918,511USD0USD———
    Total Cashflows From Investing Activities-63,453,114USD-14,338,403USD4,927,748USD-4,918,511USD————
    Total Cash From Financing Activities91,574,402USD59,292,257USD2,027,227USD32,873USD10,879,537USD8,182,120USD9,347,411USD-206,270USD
    Sale Purchase Of Stock-34,999,957USD0USD-47USD-77USD-63USD8,175,291USD10,332,220USD—
    Issuance Of Capital Stock127,141,529USD59,396,393USD1,843,663USD109,337USD10,925,312USD8,175,291USD10,222,224USD0USD
    Change In Cash16,017,263USD38,550,209USD-920,114USD-12,117,675USD3,566,760USD3,523,180USD6,321,157USD-2,889,153USD
    Begin Period Cash Flow45,816,289USD7,266,080USD8,186,194USD20,303,869USD16,737,109USD13,213,929USD6,892,772USD9,781,925USD
    End Period Cash Flow61,833,552USD45,816,289USD7,266,080USD8,186,194USD20,303,869USD16,737,109USD13,213,929USD6,892,772USD
    Other Cashflows From Financing Activities-1,132,341USD-104,136USD-46,969USD-76,464USD-45,775USD-115,571USD-874,813USD-206,270USD
    Unclassified Operating Cash Flow-4,121,413,000USD—-1,895,951USD—-1,064,087USD———
    Unclassified Financing Cash Flow127,706,700USD59,396,393USD2,074,243USD—10,925,375USD———
    Unclassified Investing Cash Flow——7,888,949USD—————
    Other Cashflows From Investing Activities———-4,919USD————
    Change To Liabilities————403,967USD447,598USD243,534USD87,684USD
    Net Borrowings————0USD122,400USD122,400USD122,400USD
    Cash And Cash Equivalents Changes—————3,523,180USD——
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    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    No revenue breakdown is currently published for this company.

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.