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    Monte Rosa Therapeutics, Inc.

    Company overview

    Market capitalization
    $999.02M
    Employees
    187
    Latest publication
    2026-09-29
    About Monte Rosa Therapeutics, Inc.

    Monte Rosa Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of novel small molecule precision medicines that employ the body's natural mechanisms to selectively degrade therapeutically relevant proteins. The company develops orally bioavailable molecular glue degraders (MGDs), such as MRT-2359 for the treatment of MYC-driven tumors; MRT-6160 for the treatment of neurologic and systemic autoimmune and inflammatory diseases; and MRT-8102 for the treatment of inflammatory diseases driven by IL-1a, IL-1ß and IL-18, as well as damage-associated molecular patterns. In addition, it develops CDK2 to treat multiple cancers, including ovarian, endometrial, gastric and breast. Further, its pipeline includes programs in immunology and inflammation indications, oncology, cardiovascular, metabolic, and genetic diseases. The company also develops QuEEN, a discovery engine, to enable its target-centric MGD discovery and development approach and its rational design of MGD product candidates. It has a strategic collaboration and licensing agreement with F. Hoffmann-La Roche Ltd.; and Novartis. The company was incorporated in 2019 and is headquartered in Boston, Massachusetts.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ4 20232023-12-31 · USD
    Total Revenue8,968,000USD2,781,000USD12,768,000USD23,194,000USD84,929,000USD60,647,000USD9,216,000USD8,752,000USD
    Research Development47,964,000USD41,979,000USD36,678,000USD30,653,000USD32,190,000USD38,866,000USD27,616,000USD27,135,000USD
    General And Administrative Expenses10,134,000USD———————
    Total Operating Expenses58,098,000USD52,496,000USD45,743,000USD38,748,000USD40,893,000USD47,643,000USD35,743,000USD34,863,000USD
    Operating Income-49,130,000USD-49,715,000USD-32,975,000USD-15,554,000USD44,036,000USD13,004,000USD-26,527,000USD-34,863,000USD
    Total Other Income Expense Net5,941,000USD3,639,000USD2,717,000USD4,458,000USD3,671,000USD2,597,000USD2,739,000USD1,589,000USD
    Income Before Tax-43,189,000USD-46,076,000USD-30,258,000USD-11,096,000USD47,707,000USD15,601,000USD-23,788,000USD-33,274,000USD
    Income Tax Expense208,000USD59,000USD-3,177,000USD1,199,000USD822,000USD2,164,000USD71,000USD-22,000USD
    Net Income-43,397,000USD-46,135,000USD-27,081,000USD-12,295,000USD46,885,000USD13,437,000USD-23,859,000USD-33,252,000USD
    Cost Of Revenue—2,088,000USD2,095,000USD2,125,000USD—2,061,000USD2,103,000USD1,846,000USD
    Gross Profit—2,781,000USD12,768,000USD23,194,000USD84,929,000USD60,647,000USD9,216,000USD-1,846,000USD
    Selling General Administrative—10,517,000USD9,065,000USD8,095,000USD8,703,000USD8,777,000USD8,127,000USD7,728,000USD
    Interest Income—3,689,000USD2,746,000USD3,068,000USD3,439,000USD2,595,000USD2,892,000USD2,368,000USD
    Net Interest Income—3,689,000USD2,746,000USD3,068,000USD3,439,000USD2,595,000USD2,892,000USD2,368,000USD
    Tax Provision—59,000USD-3,177,000USD1,199,000USD822,000USD2,164,000USD71,000USD-22,000USD
    Net Income From Continuing Ops—-46,135,000USD-27,081,000USD-12,295,000USD46,885,000USD13,437,000USD-23,859,000USD-33,252,000USD
    Ebit—-46,076,000USD-30,258,000USD-11,096,000USD47,707,000USD15,601,000USD-23,788,000USD-33,274,000USD
    Ebitda—-43,988,000USD-28,163,000USD-8,971,000USD49,755,000USD17,662,000USD-21,685,000USD-31,428,000USD
    Depreciation And Amortization—2,088,000USD2,095,000USD2,125,000USD2,048,000USD2,061,000USD2,103,000USD1,846,000USD
    Reconciled Depreciation—2,088,000USD2,095,000USD2,125,000USD2,048,000USD2,061,000USD2,103,000USD1,846,000USD
    Interest Expense———————935,000USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20232023-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USD
    Total Revenue0USD0USD0USD
    Cost Of Revenue6,222,000USD537,000USD72,000USD
    Gross Profit-6,222,000USD-537,000USD-72,000USD
    Research Development105,050,000USD23,468,000USD7,350,000USD
    Selling General Administrative32,039,000USD4,005,000USD644,000USD
    Total Operating Expenses137,089,000USD27,473,000USD7,994,000USD
    Operating Income-143,311,000USD-28,010,000USD-7,994,000USD
    Interest Income8,956,000USD9,000USD—
    Net Interest Income8,956,000USD9,000USD-1,000USD
    Income Before Tax-135,014,000USD-35,879,000USD-7,740,000USD
    Income Tax Expense338,000USD189,000USD277,000USD
    Tax Provision338,000USD——
    Net Income-135,352,000USD-35,879,000USD-8,017,000USD
    Net Income From Continuing Ops-132,882,000USD-35,879,000USD-7,740,000USD
    Ebit-135,014,000USD-28,010,000USD-7,739,000USD
    Ebitda-128,792,000USD-27,473,000USD-7,667,000USD
    Depreciation And Amortization6,222,000USD537,000USD72,000USD
    Reconciled Depreciation5,446,000USD537,000USD72,000USD
    Total Other Income Expense Net8,297,000USD-7,869,000USD254,000USD
    Interest Expense—9,000USD1,000USD
    Net Income Applicable To Common Shares—-35,879,000USD-92,880,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets691,161,000USD736,428,000USD448,659,000USD459,841,000USD359,586,000USD393,199,000USD438,732,000USD315,080,000USD
    Cash And Equivalents90,104,000USD———————
    Total Current Assets631,406,000USD677,547,000USD393,185,000USD401,817,000USD299,465,000USD332,280,000USD377,440,000USD251,207,000USD
    Other Current Assets5,382,000USD6,718,000USD11,481,000USD5,594,000USD6,501,000USD4,798,000USD5,118,000USD8,426,000USD
    Other Non Current Assets828,000USD———————
    Total Liabilities203,880,000USD———————
    Total Current Liabilities59,658,000USD71,036,000USD64,212,000USD61,443,000USD41,852,000USD59,216,000USD156,946,000USD41,641,000USD
    Total Stockholder Equity487,281,000USD521,916,000USD233,056,000USD245,837,000USD268,080,000USD275,160,000USD222,936,000USD205,457,000USD
    Total Equity Including Noncontrolling Interest487,281,000USD———————
    Deferred Revenue22,103,000USD———————
    Property Plant Equipment Net53,988,000USD53,102,000USD50,372,000USD52,663,000USD54,726,000USD55,599,000USD56,314,000USD58,806,000USD
    Accounts Payable7,152,000USD7,900,000USD3,550,000USD14,509,000USD5,581,000USD6,489,000USD17,215,000USD3,978,000USD
    Short Term Debt4,630,000USD4,483,000USD4,397,000USD4,241,000USD4,094,000USD3,865,000USD3,714,000USD3,646,000USD
    Common Stock9,000USD8,000USD7,000USD6,000USD6,000USD6,000USD6,000USD6,000USD
    Retained Earnings-565,114,000USD-521,717,000USD-477,214,000USD-431,079,000USD-403,998,000USD-391,703,000USD-438,588,000USD-452,025,000USD
    Accumulated Other Comprehensive Income-5,165,000USD-4,746,000USD-3,827,000USD-3,247,000USD-3,373,000USD-3,329,000USD-3,356,000USD-2,322,000USD
    Total Liab—214,512,000USD215,603,000USD214,004,000USD91,506,000USD118,039,000USD215,796,000USD109,623,000USD
    Other Current Liab—25,594,000USD26,694,000USD17,902,000USD13,767,000USD16,287,000USD18,785,000USD15,099,000USD
    Capital Stock—8,000USD7,000USD6,000USD6,000USD6,000USD6,000USD6,000USD
    Cash—159,859,000USD129,883,000USD208,343,000USD69,429,000USD78,530,000USD224,254,000USD125,575,000USD
    Cash And Short Term Investments—666,220,000USD377,104,000USD391,258,000USD290,594,000USD326,074,000USD372,149,000USD242,186,000USD
    Current Deferred Revenue—33,059,000USD29,571,000USD24,791,000USD18,410,000USD32,575,000USD117,232,000USD18,918,000USD
    Net Debt—-120,795,000USD-90,692,000USD-168,175,000USD-28,298,000USD-36,666,000USD-181,539,000USD-81,877,000USD
    Short Long Term Debt Total—39,064,000USD39,191,000USD40,168,000USD41,131,000USD41,864,000USD42,715,000USD43,698,000USD
    Short Term Investments—506,361,000USD247,221,000USD182,915,000USD221,165,000USD247,544,000USD147,895,000USD116,611,000USD
    Net Receivables—4,609,000USD4,600,000USD4,965,000USD2,370,000USD1,408,000USD173,000USD595,000USD
    Property Plant Equipment Gross—82,746,000USD77,985,000USD78,187,000USD78,155,000USD76,904,000USD76,678,000USD77,110,000USD
    Common Stock Shares Outstanding—65,543,723shares65,543,723shares82,397,753shares82,186,768shares82,956,423shares61,436,740shares82,011,670shares
    Non Current Assets Total—58,881,000USD55,474,000USD58,024,000USD60,121,000USD60,919,000USD61,292,000USD63,873,000USD
    Non Current Liabilities Total—143,476,000USD151,391,000USD152,561,000USD49,654,000USD58,823,000USD58,850,000USD67,982,000USD
    Non Currrent Assets Other—5,779,000USD5,102,000USD5,361,000USD445,000USD5,320,000USD4,978,000USD159,000USD
    Net Working Capital—606,511,000USD328,973,000USD340,374,000USD257,613,000USD273,064,000USD220,494,000USD209,566,000USD
    Unclassified Non Current Liabilities—143,476,000USD151,391,000USD152,561,000USD49,654,000USD58,823,000USD58,850,000USD67,982,000USD
    Unclassified Equity—1,048,363,000USD714,083,000USD680,151,000USD675,439,000USD670,180,000USD664,868,000USD659,792,000USD
    Unclassified Non Current Assets————4,950,000USD——4,908,000USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USD
    Total Assets448,659,000USD438,732,000USD303,755,000USD342,389,000USD366,329,000USD49,378,000USD11,094,000USD
    Other Current Assets11,481,000USD5,118,000USD3,294,000USD5,404,000USD2,595,000USD1,892,000USD3,764,000USD
    Total Liab215,603,000USD215,796,000USD124,505,000USD70,976,000USD18,814,000USD98,106,000USD23,242,000USD
    Total Stockholder Equity233,056,000USD222,936,000USD179,250,000USD271,413,000USD347,515,000USD-48,728,000USD-12,148,000USD
    Other Current Liab26,694,000USD18,785,000USD14,600,000USD14,580,000USD10,080,000USD22,209,000USD347,000USD
    Common Stock7,000USD6,000USD5,000USD5,000USD5,000USD1,000USD50,000USD
    Capital Stock7,000USD6,000USD5,000USD5,000USD5,000USD1,000USD50,000USD
    Retained Earnings-477,214,000USD-438,588,000USD-365,888,000USD-230,536,000USD-122,035,000USD-48,077,000USD-12,198,000USD
    Cash129,883,000USD224,254,000USD128,101,000USD54,912,000USD346,071,000USD41,699,000USD5,995,000USD
    Cash And Short Term Investments377,104,000USD372,149,000USD232,413,000USD262,826,000USD346,071,000USD41,699,000USD5,995,000USD
    Total Current Assets393,185,000USD377,440,000USD236,212,000USD275,886,000USD348,666,000USD43,591,000USD9,759,000USD
    Total Current Liabilities64,212,000USD156,946,000USD46,592,000USD25,569,000USD16,638,000USD29,275,000USD4,292,000USD
    Current Deferred Revenue29,571,000USD117,232,000USD17,678,000USD————
    Net Debt-90,692,000USD-181,539,000USD-82,062,000USD-7,911,000USD-346,071,000USD26,065,000USD-5,245,000USD
    Short Term Debt4,397,000USD3,714,000USD3,162,000USD3,127,000USD——750,000USD
    Short Long Term Debt Total39,191,000USD42,715,000USD46,039,000USD47,001,000USD—67,764,000USD750,000USD
    Short Term Investments247,221,000USD147,895,000USD104,312,000USD207,914,000USD0USD——
    Net Receivables4,600,000USD173,000USD505,000USD7,656,000USD—79,000USD51,000USD
    Accounts Payable3,550,000USD17,215,000USD11,152,000USD7,862,000USD6,558,000USD7,066,000USD3,195,000USD
    Property Plant Equipment Net50,372,000USD56,314,000USD62,611,000USD61,907,000USD12,325,000USD4,623,000USD1,335,000USD
    Property Plant Equipment Gross77,985,000USD76,678,000USD74,855,000USD61,907,000USD15,028,000USD4,623,000USD1,335,000USD
    Accumulated Other Comprehensive Income-3,827,000USD-3,356,000USD-2,724,000USD-1,752,000USD-2,021,000USD-1,056,000USD-68,950USD
    Common Stock Shares Outstanding83,071,185shares73,910,026shares51,396,961shares47,227,370shares46,535,966shares44,002,715shares44,002,715shares
    Non Current Assets Total55,474,000USD61,292,000USD67,543,000USD66,503,000USD17,663,000USD5,787,000USD1,335,000USD
    Non Current Liabilities Total151,391,000USD58,850,000USD77,913,000USD45,407,000USD2,176,000USD68,831,000USD18,950,000USD
    Non Currrent Assets Other5,102,000USD4,978,000USD4,932,000USD4,596,000USD5,338,000USD1,164,000USD—
    Net Working Capital328,973,000USD220,494,000USD189,620,000USD250,317,000USD332,028,000USD14,316,000USD5,467,000USD
    Unclassified Non Current Liabilities151,391,000USD58,850,000USD77,913,000USD-1,533,000USD-2,176,000USD67,764,000USD18,950,000USD
    Unclassified Equity714,083,000USD664,868,000USD547,852,000USD503,691,000USD471,561,000USD——
    Other Liab———1,533,000USD2,176,000USD1,067,000USD—
    Other Assets———4,596,000USD5,338,000USD1,164,000USD—
    Inventory———960,000USD———
    Non Current Liabilities Other———45,407,000USD2,176,000USD——
    Net Tangible Assets———271,413,000USD347,515,000USD-48,728,000USD-12,148,000USD
    Unclassified Non Current Assets———-4,596,000USD-5,338,000USD-1,164,000USD—
    Short Long Term Debt——————750,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-44,503,000USD-46,135,000USD-27,081,000USD-12,295,000USD46,885,000USD13,437,000USD-23,859,000USD-30,310,000USD
    Depreciation2,029,000USD2,088,000USD2,095,000USD2,125,000USD2,048,000USD2,061,000USD2,103,000USD2,060,000USD
    Stock Based Compensation5,949,000USD4,309,000USD4,364,000USD4,894,000USD5,298,000USD4,469,000USD4,282,000USD4,502,000USD
    Other Non Cash Items-985,000USD87,000USD-466,000USD-737,000USD-1,088,000USD-696,000USD-1,089,000USD-1,094,000USD
    Change To Account Receivables6,991,000USD-2,208,000USD-2,596,000USD-961,000USD-1,235,000USD422,000USD9,247,000USD-9,327,000USD
    Change In Working Capital141,000USD-3,363,000USD121,516,000USD-28,707,000USD-98,635,000USD109,651,000USD-2,431,000USD-2,925,000USD
    Total Cash From Operating Activities-37,369,000USD-43,014,000USD100,428,000USD-34,720,000USD-45,492,000USD128,922,000USD-20,994,000USD-27,767,000USD
    Capital Expenditures-1,868,000USD-767,000USD-651,000USD-1,695,000USD-1,587,000USD-183,000USD-399,000USD-2,022,000USD
    Free Cash Flow-39,237,000USD-43,781,000USD99,777,000USD-36,415,000USD-47,079,000USD128,739,000USD-21,393,000USD-29,789,000USD
    Investments-259,129,000USD-64,299,000USD38,138,000USD25,324,000USD-100,229,000USD-30,896,000USD37,749,000USD-61,158,000USD
    Total Cashflows From Investing Activities-260,997,000USD-65,066,000USD38,138,000USD25,324,000USD-100,229,000USD-30,896,000USD37,749,000USD-61,158,000USD
    Total Cash From Financing Activities328,335,000USD29,624,000USD348,000USD365,000USD14,000USD608,000USD15,000USD98,023,000USD
    Issuance Of Capital Stock324,300,000USD24,250,000USD0USD0USD0USD-47,001,000USD0USD—
    Change In Cash29,976,000USD-78,456,000USD138,914,000USD-9,031,000USD-145,724,000USD98,634,000USD16,770,000USD9,095,000USD
    Begin Period Cash Flow129,883,000USD213,293,000USD74,379,000USD83,410,000USD224,254,000USD130,483,000USD113,713,000USD99,752,000USD
    End Period Cash Flow159,859,000USD134,837,000USD213,293,000USD74,379,000USD78,530,000USD229,117,000USD130,483,000USD108,847,000USD
    Unclassified Financing Cash Flow4,035,000USD————-47,001,000USD——
    Sale Purchase Of Stock—-357,000USD———0USD——
    Other Cashflows From Financing Activities—29,624,000USD348,000USD—14,000USD47,609,000USD15,000USD98,023,000USD
    Other Cashflows From Investing Activities——38,789,000USD———38,148,000USD-59,136,000USD
    Unclassified Investing Cash Flow——-38,138,000USD1,695,000USD1,587,000USD—-37,749,000USD61,158,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USD
    Net Income-38,626,000USD-72,700,000USD-135,352,000USD-108,501,000USD-73,958,000USD-35,879,000USD-7,740,000USD
    Depreciation8,356,000USD8,121,000USD6,222,000USD3,745,000USD2,132,000USD537,000USD72,000USD
    Stock Based Compensation18,865,000USD18,126,000USD16,669,000USD11,664,000USD5,200,000USD354,000USD0USD
    Other Non Cash Items-2,204,000USD-2,948,000USD-3,807,000USD2,760,000USD960,000USD7,680,000USD-276,000USD
    Change To Account Receivables-7,000,000USD332,000USD1,897,000USD-187USD-187,000USD-187,000USD-187,000USD
    Change In Working Capital-9,189,000USD91,397,000USD72,466,000USD-2,134,000USD6,286,000USD4,255,000USD1,771,000USD
    Total Cash From Operating Activities-22,798,000USD41,996,000USD-43,802,000USD-92,466,000USD-59,363,000USD-23,053,000USD-6,173,000USD
    Capital Expenditures-4,700,000USD-3,988,000USD-19,041,000USD-12,911,000USD-9,732,000USD-3,389,000USD-1,385,000USD
    Free Cash Flow-27,498,000USD38,008,000USD-62,843,000USD-105,377,000USD-69,095,000USD-26,442,000USD-7,558,000USD
    Investments-97,133,000USD-44,452,000USD20,565,000USD-206,417,000USD-9,653,000USD-3,389,000USD-1,385,000USD
    Total Cashflows From Investing Activities-101,833,000USD-44,452,000USD88,801,000USD-219,219,000USD-9,653,000USD-3,389,000USD-1,385,000USD
    Total Cash From Financing Activities30,351,000USD98,892,000USD27,492,000USD20,466,000USD377,562,000USD60,060,000USD15,000,000USD
    Sale Purchase Of Stock-357,000USD-641,000USD-116,000USD20,830,000USD377,562,000USD-440,000USD0USD
    Issuance Of Capital Stock24,250,000USD944,000USD0USD20,055,000USD380,750,000USD60,500,000USD14,250,000USD
    Change In Cash-94,280,000USD96,436,000USD72,491,000USD-291,219,000USD308,546,000USD32,454,000USD7,442,000USD
    Begin Period Cash Flow229,117,000USD132,681,000USD60,190,000USD351,409,000USD42,863,000USD9,245,000USD1,803,000USD
    End Period Cash Flow134,837,000USD229,117,000USD132,681,000USD60,190,000USD351,409,000USD41,699,000USD9,245,000USD
    Other Cashflows From Financing Activities30,351,000USD98,589,000USD27,492,000USD411,000USD139,812,000USD60,500,000USD14,250,000USD
    Unclassified Investing Cash Flow—3,988,000USD87,215,000USD—9,731,921USD3,389,000USD1,385,000USD
    Change To Inventory——-1,897USD187USD———
    Other Cashflows From Investing Activities——62,000USD-206,308USD79USD——
    Change To Liabilities———287,000USD5,881,000USD3,435,000USD34,320,000USD
    Cash And Cash Equivalents Changes———-291,219,000USD308,546,000USD——
    Unclassified Financing Cash Flow————-139,812,000USD—-8,250,000USD
    Net Borrowings——————9,000,000USD
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    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    No revenue breakdown is currently published for this company.

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.