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    DNLI

    Denali Therapeutics Inc.

    Company overview

    Market capitalization
    $3.35B
    Employees
    507
    Latest publication
    2026-09-29
    About Denali Therapeutics Inc.

    Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Total Revenue0USD0USD0USD0USD0USD0USD0USD0USD
    Cost Of Revenue2,845,000USD2,866,000USD101,950,000USD3,045,000USD———1,942,000USD
    Gross Profit-2,845,000USD-2,866,000USD-101,950,000USD-3,045,000USD———-1,942,000USD
    Research Development103,846,000USD97,905,000USD101,950,000USD102,696,000USD116,227,000USD99,787,000USD98,238,000USD91,399,000USD
    Selling General Administrative33,511,000USD39,460,000USD35,484,000USD32,267,000USD29,353,000USD30,059,000USD24,949,000USD25,194,000USD
    Unclassified Operating Expenses-2,845,000USD-2,866,000USD——————
    Total Operating Expenses134,512,000USD134,499,000USD137,434,000USD134,963,000USD145,580,000USD129,846,000USD123,187,000USD116,593,000USD
    Operating Income-137,357,000USD-137,365,000USD-137,434,000USD-134,963,000USD-145,580,000USD-129,846,000USD-123,187,000USD-116,593,000USD
    Interest Income8,910,000USD8,918,000USD10,532,000USD10,844,000USD12,610,000USD15,161,000USD15,995,000USD17,567,000USD
    Net Interest Income8,910,000USD8,918,000USD10,532,000USD10,844,000USD12,610,000USD15,161,000USD15,995,000USD17,567,000USD
    Income Before Tax-128,447,000USD-128,447,000USD-126,902,000USD-124,119,000USD-132,970,000USD-114,685,000USD-107,192,000USD-99,026,000USD
    Net Income-128,447,000USD-128,549,000USD-126,902,000USD-124,119,000USD-132,970,000USD-114,753,000USD-107,192,000USD-99,026,000USD
    Net Income From Continuing Ops-128,447,000USD-128,549,000USD-126,902,000USD-124,119,000USD-132,970,000USD-114,753,000USD-107,192,000USD-99,026,000USD
    Ebit-137,357,000USD-128,447,000USD-137,434,000USD-134,963,000USD-145,580,000USD-129,846,000USD-123,187,000USD-116,593,000USD
    Ebitda-134,512,000USD-124,665,000USD-133,572,000USD-131,007,000USD-142,368,000USD-127,227,000USD-120,918,000USD-114,651,000USD
    Depreciation And Amortization2,845,000USD3,782,000USD3,862,000USD3,956,000USD3,212,000USD2,619,000USD2,269,000USD1,942,000USD
    Reconciled Depreciation3,761,000USD3,782,000USD3,862,000USD3,956,000USD3,212,000USD2,619,000USD2,269,000USD1,942,000USD
    Total Other Income Expense Net8,910,000USD8,918,000USD10,532,000USD10,844,000USD12,610,000USD15,161,000USD15,995,000USD17,567,000USD
    Income Tax Expense—102,000USD———68,000USD——
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Revenue0USD0USD330,531,000USD108,463,000USD48,661,000USD335,659,000USD26,678,000USD129,160,000USD
    Cost Of Revenue11,183,000USD7,795,000USD16,726,000USD7,032,000USD5,609,000USD212,615,000USD193,382,000USD143,183,000USD
    Gross Profit-11,183,000USD-7,795,000USD330,531,000USD108,463,000USD48,661,000USD335,659,000USD26,678,000USD129,160,000USD
    Research Development418,778,000USD396,440,000USD423,876,000USD358,732,000USD265,353,000USD212,615,000USD193,382,000USD143,183,000USD
    Selling General Administrative97,104,000USD105,438,000USD103,354,000USD90,475,000USD79,059,000USD60,326,000USD46,480,000USD32,349,000USD
    Unclassified Operating Expenses28,277,000USD-14,537,000USD——————
    Total Operating Expenses544,159,000USD487,341,000USD527,230,000USD449,207,000USD344,412,000USD272,941,000USD239,862,000USD175,532,000USD
    Operating Income-555,342,000USD-487,341,000USD-196,699,000USD-340,744,000USD-295,751,000USD62,718,000USD-213,184,000USD-46,372,000USD
    Interest Income42,904,000USD64,636,000USD51,505,000USD14,774,000USD4,595,000USD9,241,000USD15,219,000USD10,132,000USD
    Net Interest Income42,904,000USD64,636,000USD45,036,000USD14,774,000USD4,595,000USD9,241,000USD15,219,000USD10,132,000USD
    Income Before Tax-512,438,000USD-422,705,000USD-145,194,000USD-325,970,000USD-291,156,000USD71,959,000USD-197,965,000USD-36,240,000USD
    Income Tax Expense102,000USD68,000USD30,000USD21,000USD-575,000USD823,000USD-351,000USD10,132,000USD
    Tax Provision102,000USD68,000USD-6,000USD21,000USD-575,000USD823,000USD-351,000USD—
    Net Income-512,540,000USD-422,773,000USD-145,224,000USD-325,991,000USD-290,581,000USD71,136,000USD-197,614,000USD-36,240,000USD
    Net Income From Continuing Ops-512,540,000USD-422,773,000USD-124,429,000USD-325,991,000USD-290,581,000USD72,782,000USD-197,614,000USD-36,240,000USD
    Ebit-512,438,000USD-501,878,000USD-196,699,000USD-340,744,000USD-295,751,000USD62,718,000USD-213,184,000USD-46,372,000USD
    Ebitda-497,626,000USD-492,886,000USD-179,973,000USD-330,361,000USD-287,158,000USD71,249,000USD-205,193,000USD-38,957,000USD
    Depreciation And Amortization14,812,000USD8,992,000USD16,726,000USD10,383,000USD8,593,000USD8,531,000USD7,991,000USD7,415,000USD
    Reconciled Depreciation14,812,000USD8,992,000USD18,640,000USD10,383,000USD8,593,000USD8,531,000USD7,991,000USD7,415,000USD
    Total Other Income Expense Net42,904,000USD64,636,000USD51,505,000USD14,774,000USD4,595,000USD9,241,000USD15,219,000USD10,132,000USD
    Interest Expense———14,774,000USD13,188,000USD17,772,000USD15,219,000USD1,955,000USD
    Net Income Applicable To Common Shares———-325,991,000USD-290,581,000USD71,136,000USD-197,614,000USD-36,240,000USD
    Non Operating Income Net Other————4,595,000USD9,241,000USD15,219,000USD10,132,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Total Assets1,266,023,000USD1,144,854,000USD1,055,621,000USD1,166,241,000USD1,271,343,000USD1,374,180,000USD1,454,013,000USD1,502,565,000USD
    Intangible Assets36,000,000USD———————
    Other Current Assets33,468,000USD30,602,000USD32,494,000USD35,754,000USD60,712,000USD29,934,000USD32,280,000USD32,339,000USD
    Total Liab339,925,000USD131,093,000USD129,424,000USD139,188,000USD148,657,000USD144,496,000USD135,518,000USD115,514,000USD
    Total Stockholder Equity926,098,000USD1,013,761,000USD926,197,000USD1,027,053,000USD1,122,686,000USD1,229,684,000USD1,318,495,000USD1,387,051,000USD
    Other Current Liab44,801,000USD85,475,000USD51,657,000USD71,342,000USD74,834,000USD79,037,000USD69,463,000USD52,826,000USD
    Common Stock1,913,000USD1,888,000USD1,793,000USD1,783,000USD1,778,000USD1,768,000USD1,764,000USD1,757,000USD
    Capital Stock1,913,000USD1,888,000USD1,793,000USD1,783,000USD1,778,000USD1,768,000USD1,764,000USD1,757,000USD
    Retained Earnings-2,179,971,000USD-2,051,524,000USD-1,922,975,000USD-1,796,073,000USD-1,671,954,000USD-1,538,984,000USD-1,424,231,000USD-1,317,039,000USD
    Cash387,626,000USD205,326,000USD90,963,000USD141,207,000USD56,947,000USD174,960,000USD90,636,000USD74,679,000USD
    Cash And Short Term Investments987,684,000USD867,879,000USD848,204,000USD898,952,000USD817,926,000USD832,331,000USD836,559,000USD896,044,000USD
    Total Current Assets1,022,752,000USD900,658,000USD882,598,000USD934,706,000USD878,638,000USD864,436,000USD868,839,000USD928,383,000USD
    Total Current Liabilities110,156,000USD98,351,000USD90,146,000USD91,057,000USD91,877,000USD102,208,000USD87,093,000USD74,533,000USD
    Current Deferred Revenue15,116,000USD—22,580,000USD———14,874,000USD—
    Net Debt-347,579,000USD-163,038,000USD-46,559,000USD-94,649,000USD-8,315,000USD-126,253,000USD-38,119,000USD-25,927,000USD
    Short Term Debt9,859,000USD9,546,000USD9,164,000USD8,871,000USD8,585,000USD12,034,000USD8,036,000USD7,771,000USD
    Short Long Term Debt Total40,047,000USD42,287,999USD44,404,000USD46,558,000USD48,632,000USD48,707,000USD52,517,000USD48,752,000USD
    Long Term Investments63,785,000USD98,322,000USD24,703,000USD78,463,000USD235,844,000USD359,373,000USD445,463,000USD450,994,000USD
    Short Term Investments600,058,000USD662,553,000USD757,241,000USD757,745,000USD760,979,000USD657,371,000USD745,923,000USD821,365,000USD
    Net Receivables1,600,000USD2,177,000USD1,900,000USD1,400,000USD—2,171,000USD—1,400,000USD
    Accounts Payable40,380,000USD3,330,000USD6,745,000USD10,844,000USD8,458,000USD11,137,000USD9,594,000USD13,936,000USD
    Property Plant Equipment Net117,266,000USD119,935,000USD123,214,000USD130,102,000USD129,927,000USD125,630,000USD113,224,000USD72,610,000USD
    Property Plant Equipment Gross117,266,000USD182,830,000USD123,214,000USD130,102,000USD129,927,000USD177,672,000USD113,224,000USD72,610,000USD
    Accumulated Other Comprehensive Income-682,000USD682,000USD1,101,000USD939,000USD2,037,000USD2,020,000USD5,529,000USD-2,659,000USD
    Common Stock Shares Outstanding186,636,978shares175,458,962shares172,421,492shares171,449,847shares171,222,030shares170,086,146shares169,456,988shares168,831,329shares
    Non Current Assets Total243,270,999USD244,196,000USD173,023,000USD231,535,000USD392,705,000USD509,744,000USD585,174,000USD574,182,000USD
    Non Current Liabilities Total229,769,000USD32,742,000USD39,278,000USD48,131,000USD56,780,000USD42,288,000USD48,425,000USD40,981,000USD
    Non Current Liabilities Other5,508,000USD5,532,000USD———5,615,000USD——
    Non Currrent Assets Other23,119,999USD22,839,000USD22,006,000USD22,970,000USD26,934,000USD24,741,000USD26,487,000USD50,578,000USD
    Net Working Capital912,596,000USD802,307,000USD792,452,000USD843,649,000USD786,761,000USD762,228,000USD781,746,000USD853,850,000USD
    Unclassified Non Current Assets3,100,000USD3,100,000USD3,100,000USD—————
    Unclassified Non Current Liabilities224,261,000USD27,210,000USD39,278,000USD48,131,000USD56,780,000USD36,673,000USD48,425,000USD40,981,000USD
    Unclassified Equity3,102,925,000USD3,060,827,000USD2,844,485,000USD2,818,621,000USD2,789,047,000USD2,763,112,000USD2,733,669,000USD2,703,235,000USD
    Unclassified Current Liabilities——————-14,874,000USD—
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Assets1,144,854,000USD1,374,180,000USD1,153,917,000USD1,460,242,000USD1,404,162,000USD1,604,280,000USD553,231,000USD661,984,000USD
    Other Current Assets30,602,000USD29,934,000USD26,206,000USD26,822,000USD30,601,000USD25,958,000USD14,675,000USD7,993,000USD
    Total Liab131,093,000USD144,496,000USD122,963,000USD417,812,000USD441,871,000USD453,749,000USD158,341,000USD115,139,000USD
    Total Stockholder Equity1,013,761,000USD1,229,684,000USD1,030,954,000USD1,042,430,000USD962,291,000USD1,150,531,000USD394,890,000USD546,845,000USD
    Other Current Liab85,475,000USD79,037,000USD61,239,000USD63,761,000USD47,712,000USD42,455,000USD20,350,000USD19,468,000USD
    Common Stock1,888,000USD1,768,000USD1,711,000USD1,686,000USD1,548,000USD1,531,000USD1,288,000USD1,273,000USD
    Capital Stock1,888,000USD1,768,000USD1,711,000USD1,686,000USD1,548,000USD1,531,000USD1,288,000USD1,273,000USD
    Retained Earnings-2,051,524,000USD-1,538,984,000USD-1,116,211,000USD-970,987,000USD-644,996,000USD-354,415,000USD-425,551,000USD-227,937,000USD
    Cash205,326,000USD174,960,000USD127,106,000USD218,044,000USD293,477,000USD507,144,000USD79,449,000USD77,123,000USD
    Cash And Short Term Investments867,879,000USD832,331,000USD1,034,511,000USD1,336,215,000USD865,407,000USD1,469,697,000USD415,356,000USD464,297,000USD
    Total Current Assets900,658,000USD864,436,000USD1,064,137,000USD1,372,319,000USD897,234,000USD1,495,655,000USD430,031,000USD480,836,000USD
    Total Current Liabilities98,351,000USD102,208,000USD77,982,000USD363,922,000USD378,245,000USD71,699,000USD45,344,000USD32,786,000USD
    Net Debt-163,038,000USD-126,253,000USD-74,865,000USD-157,694,000USD-229,470,000USD-438,279,000USD-6,919,000USD-77,123,000USD
    Short Term Debt9,546,000USD12,034,000USD7,260,000USD7,318,000USD5,453,000USD4,690,000USD3,665,000USD19,088,000USD
    Short Long Term Debt Total42,287,999USD48,707,000USD52,241,000USD60,350,000USD64,007,000USD68,865,000USD72,530,000USD—
    Long Term Investments98,322,000USD359,373,000USD0USD0USD425,449,000USD32,699,000USD39,886,000USD147,881,000USD
    Short Term Investments662,553,000USD657,371,000USD907,405,000USD1,118,171,000USD571,930,000USD962,553,000USD335,907,000USD387,174,000USD
    Net Receivables2,177,000USD2,171,000USD3,420,000USD9,282,000USD1,226,000USD5,674,000USD—8,546,000USD
    Accounts Payable3,330,000USD11,137,000USD9,483,000USD2,790,000USD4,779,000USD1,071,000USD2,590,000USD1,891,000USD
    Property Plant Equipment Net119,935,000USD125,630,000USD71,637,000USD74,524,000USD69,608,000USD73,464,000USD80,655,000USD25,162,000USD
    Property Plant Equipment Gross182,830,000USD177,672,000USD117,640,000USD74,524,000USD69,608,000USD73,464,000USD80,655,000USD14,923,000USD
    Accumulated Other Comprehensive Income682,000USD2,020,000USD643,000USD-6,886,000USD-2,499,000USD-245,000USD350,000USD-649,000USD
    Common Stock Shares Outstanding175,458,962shares164,473,772shares137,370,897shares125,530,703shares121,524,795shares112,703,108shares95,608,208shares92,621,991shares
    Non Current Assets Total244,196,000USD509,744,000USD89,780,000USD87,923,000USD506,928,000USD108,625,000USD123,200,000USD181,148,000USD
    Non Current Liabilities Total32,742,000USD42,288,000USD44,981,000USD53,890,000USD63,626,000USD382,050,000USD112,997,000USD82,353,000USD
    Non Current Liabilities Other5,532,000USD5,615,000USD—379,000USD379,000USD382,050,000USD379,000USD471,000USD
    Non Currrent Assets Other124,261,000USD24,741,000USD18,143,000USD13,399,000USD11,871,000USD962,000USD2,659,000USD8,105,000USD
    Net Working Capital802,307,000USD762,228,000USD986,155,000USD1,008,397,000USD518,989,000USD1,423,956,000USD384,687,000USD448,050,000USD
    Unclassified Non Current Assets-98,322,000USD——-13,399,000USD-11,871,000USD—-2,659,000USD-8,105,000USD
    Unclassified Non Current Liabilities27,210,000USD36,673,000USD44,981,000USD52,653,000USD58,175,000USD-317,875,000USD68,486,000USD-6,312,000USD
    Unclassified Equity3,060,827,000USD2,763,112,000USD2,143,100,000USD2,016,931,000USD1,606,690,000USD1,502,129,000USD817,515,000USD772,885,000USD
    Other Assets——1USD13,399,000USD11,871,000USD2,462,000USD2,659,000USD8,105,000USD
    Current Deferred Revenue——-46,909,000USD290,053,000USD320,301,000USD23,483,000USD18,739,000USD11,427,000USD
    Inventory——1USD-5,000,000USD———-8,546,000USD
    Other Liab———858,000USD5,072,000USD317,875,000USD44,132,000USD82,353,000USD
    Net Tangible Assets———1,042,430,000USD962,291,000USD1,150,531,000USD394,890,000USD546,845,000USD
    Deferred Long Term Liab———————5,841,000USD
    Unclassified Current Liabilities———————-19,088,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-128,447,000USD-128,549,000USD-126,902,000USD-124,119,000USD-132,970,000USD-114,753,000USD-107,192,000USD-99,026,000USD
    Depreciation3,761,000USD3,782,000USD2,947,000USD3,045,000USD3,212,000USD1,853,000USD1,838,000USD1,942,000USD
    Stock Based Compensation23,087,000USD23,951,000USD25,135,000USD25,387,000USD25,160,000USD25,078,000USD24,860,000USD25,100,000USD
    Other Non Cash Items-2,109,000USD-2,738,000USD22,880,000USD22,489,000USD-4,937,000USD-6,448,000USD15,864,000USD-11,077,000USD
    Change In Working Capital-27,496,000USD5,016,000USD-6,221,000USD23,287,000USD-21,933,000USD10,555,000USD30,351,000USD-8,159,000USD
    Total Cash From Operating Activities-131,204,000USD-98,538,000USD-107,296,000USD-75,298,000USD-131,468,000USD-83,715,000USD-59,139,000USD-91,220,000USD
    Capital Expenditures-2,466,000USD-1,524,000USD1,378,000USD-4,278,000USD-5,078,000USD-5,092,000USD-3,884,000USD-4,786,000USD
    Free Cash Flow-133,670,000USD-100,062,000USD-105,918,000USD-79,576,000USD-136,546,000USD-88,807,000USD-63,023,000USD-96,006,000USD
    Investments96,926,000USD22,292,000USD57,830,000USD157,935,000USD18,748,000USD172,207,000USD93,655,000USD98,569,000USD
    Total Cashflows From Investing Activities94,460,000USD20,768,000USD57,830,000USD157,935,000USD18,748,000USD172,207,000USD93,655,000USD98,569,000USD
    Net Borrowings-17,000USD-16,000USD-1,361,000USD-2,434,000USD-4,357,000USD-8,323,000USD-24,015,000USD—
    Total Cash From Financing Activities219,044,000USD192,133,000USD-778,000USD1,623,000USD-3,762,000USD-4,168,000USD-18,559,000USD6,756,000USD
    Change In Cash182,300,000USD114,363,000USD-50,244,000USD84,260,000USD-116,482,000USD84,324,000USD15,957,000USD14,105,000USD
    Begin Period Cash Flow208,432,000USD94,069,000USD141,207,000USD56,947,000USD176,535,000USD92,211,000USD74,679,000USD60,574,000USD
    End Period Cash Flow390,732,000USD208,432,000USD90,963,000USD141,207,000USD60,053,000USD176,535,000USD90,636,000USD74,679,000USD
    Other Cashflows From Financing Activities200,000,000USD192,133,000USD-778,000USD1,623,000USD595,000USD4,155,000USD-18,559,000USD6,756,000USD
    Unclassified Financing Cash Flow19,061,000USD-189,233,000USD1,361,000USD2,434,000USD——24,015,000USD—
    Issuance Of Capital Stock—189,249,000USD0USD0USD0USD0USD0USD0USD
    Unclassified Operating Cash Flow——-25,135,000USD-25,387,000USD——-24,860,000USD—
    Unclassified Investing Cash Flow——-1,378,000USD4,278,000USD5,078,000USD5,092,000USD3,884,000USD-98,569,000USD
    Other Cashflows From Investing Activities———————103,355,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Net Income-512,540,000USD-422,773,000USD-145,224,000USD-325,991,000USD-290,581,000USD71,136,000USD-197,614,000USD-36,240,000USD
    Depreciation14,812,000USD8,992,000USD16,726,000USD10,383,000USD8,593,000USD8,531,000USD7,991,000USD7,415,000USD
    Stock Based Compensation99,633,000USD102,878,000USD108,102,000USD99,847,000USD85,247,000USD50,351,000USD38,378,000USD18,791,000USD
    Other Non Cash Items-14,654,000USD-53,728,000USD-47,669,000USD-4,925,000USD5,764,000USD-2,322,000USD-3,253,000USD-2,741,000USD
    Change In Working Capital149,000USD16,937,000USD-289,926,000USD-24,030,000USD-20,412,000USD288,401,000USD2,922,000USD62,891,000USD
    Total Cash From Operating Activities-412,600,000USD-347,694,000USD-357,991,000USD-244,716,000USD-211,389,000USD416,152,000USD-151,576,000USD50,116,000USD
    Capital Expenditures-9,502,000USD-15,912,000USD-12,939,000USD-17,833,000USD-8,500,000USD-3,095,000USD-17,919,000USD-3,393,000USD
    Free Cash Flow-422,102,000USD-363,606,000USD-370,930,000USD-262,549,000USD-219,889,000USD413,057,000USD-169,495,000USD46,723,000USD
    Investments264,783,000USD-88,756,000USD48,702,000USD-141,387,000USD-13,126,000USD-620,111,000USD165,631,000USD-284,029,000USD
    Total Cashflows From Investing Activities255,281,000USD-88,756,000USD249,308,000USD-141,387,000USD-21,626,000USD-623,206,000USD147,712,000USD-287,422,000USD
    Net Borrowings-8,168,000USD-32,338,000USD0USD0USD————
    Total Cash From Financing Activities189,216,000USD484,304,000USD17,820,000USD310,670,000USD19,348,000USD634,749,000USD6,190,000USD97,019,000USD
    Issuance Of Capital Stock189,249,000USD499,253,000USD0USD296,215,000USD0USD614,094,000USD193,948,000USD94,406,000USD
    Change In Cash31,897,000USD47,854,000USD-90,938,000USD-75,433,000USD-213,667,000USD427,695,000USD2,326,000USD-140,287,000USD
    Begin Period Cash Flow176,535,000USD128,681,000USD218,044,000USD294,977,000USD508,644,000USD80,949,000USD78,623,000USD218,910,000USD
    End Period Cash Flow208,432,000USD176,535,000USD127,106,000USD219,544,000USD294,977,000USD508,644,000USD80,949,000USD78,623,000USD
    Other Cashflows From Financing Activities189,216,000USD17,389,000USD17,820,000USD14,455,000USD19,348,000USD20,655,000USD6,190,000USD2,613,000USD
    Unclassified Financing Cash Flow-181,081,000USD———-19,348,000USD399,491,000USD-6,190,000USD91,793,000USD
    Unclassified Investing Cash Flow—15,912,000USD213,545,000USD141,387,000USD13,126,000USD620,111,000USD-165,631,000USD284,029,000USD
    Change To Liabilities———-32,188,000USD-11,957,000USD20,805,000USD2,533,000USD8,966,000USD
    Other Cashflows From Investing Activities———-123,554,000USD-13,126,000USD-620,111,000USD165,631,000USD-284,029,000USD
    Sale Purchase Of Stock————19,348,000USD214,603,000USD6,190,000USD2,613,000USD
    Cash And Cash Equivalents Changes————-213,667,000USD427,695,000USD2,326,000USD-140,287,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    PeriodDimensionBusiness / regionRevenueCurrencySource
    FY 2023Yearly · 2023-12-31ProductATVAbeta Option Material Right293,912,000USD0001714899-26-000021
    FY 2023Yearly · 2023-12-31ProductOption Services1,619,000USD0001714899-26-000021
    Q3 2023Quarterly · 2023-09-30ProductATVAbeta Program License0USD0001714899-23-000146
    Q3 2023Quarterly · 2023-09-30ProductCNSProgram License0USD0001714899-23-000146
    Q3 2023Quarterly · 2023-09-30ProductCollaboration Agreement Services0USD0001714899-23-000146
    Q3 2023Quarterly · 2023-09-30ProductOption Services1,267,000USD0001714899-23-000146
    Q3 2023Quarterly · 2023-09-30ProductPTVPGRNServices0USD0001714899-23-000146
    Q2 2023Quarterly · 2023-06-30ProductATVAbeta Program License293,912,000USD0001714899-23-000120
    Q2 2023Quarterly · 2023-06-30ProductCNSProgram License0USD0001714899-23-000120
    Q2 2023Quarterly · 2023-06-30ProductCollaboration Agreement Services0USD0001714899-23-000120
    Q2 2023Quarterly · 2023-06-30ProductOption Services211,000USD0001714899-23-000120
    Q2 2023Quarterly · 2023-06-30ProductPTVPGRNServices0USD0001714899-23-000120
    Q1 2023Quarterly · 2023-03-31ProductCNSProgram License25,000,000USD0001714899-24-000121
    Q1 2023Quarterly · 2023-03-31ProductOption Services141,000USD0001714899-24-000121
    Q1 2023Quarterly · 2023-03-31ProductPTVPGRNServices10,000,000USD0001714899-24-000121
    FY 2022Yearly · 2022-12-31ProductATVAbeta Option Material Right0USD0001714899-24-000086
    FY 2022Yearly · 2022-12-31ProductCNSProgram License40,000,000USD0001714899-24-000086
    FY 2022Yearly · 2022-12-31ProductCollaboration Agreement Services51,916,000USD0001714899-24-000086
    FY 2022Yearly · 2022-12-31ProductCollaborative Arrangement ATVTREM20USD0001714899-24-000086
    FY 2022Yearly · 2022-12-31ProductCollaborative Arrangement PTVPGRN0USD0001714899-24-000086
    FY 2022Yearly · 2022-12-31ProductOption Services3,149,000USD0001714899-24-000086
    FY 2022Yearly · 2022-12-31ProductPeripheral Product10,000,000USD0001714899-24-000086
    Q3 2022Quarterly · 2022-09-30ProductATVAbeta Program License0USD0001714899-23-000146
    Q3 2022Quarterly · 2022-09-30ProductCNSProgram License0USD0001714899-23-000146
    Q3 2022Quarterly · 2022-09-30ProductCollaboration Agreement Services0USD0001714899-23-000146
    Q3 2022Quarterly · 2022-09-30ProductOption Services184,000USD0001714899-23-000146
    Q3 2022Quarterly · 2022-09-30ProductPTVPGRNServices0USD0001714899-23-000146
    Q2 2022Quarterly · 2022-06-30ProductATVAbeta Program License0USD0001714899-23-000120
    Q2 2022Quarterly · 2022-06-30ProductCNSProgram License40,000,000USD0001714899-23-000120
    Q2 2022Quarterly · 2022-06-30ProductCollaboration Agreement Services12,000,000USD0001714899-23-000120
    Q2 2022Quarterly · 2022-06-30ProductOption Services480,000USD0001714899-23-000120
    Q2 2022Quarterly · 2022-06-30ProductPTVPGRNServices0USD0001714899-23-000120
    Q1 2022Quarterly · 2022-03-31ProductCNSProgram License0USD0001714899-23-000075
    Q1 2022Quarterly · 2022-03-31ProductCollaboration Agreement Services39,916,000USD0001714899-23-000075
    Q1 2022Quarterly · 2022-03-31ProductOption Services2,225,000USD0001714899-23-000075
    Q1 2022Quarterly · 2022-03-31ProductPTVPGRNServices0USD0001714899-23-000075
    FY 2021Yearly · 2021-12-31ProductCNSProgram License0USD0001714899-23-000049
    FY 2021Yearly · 2021-12-31ProductCollaboration Agreement Services19,921,000USD0001714899-23-000049
    FY 2021Yearly · 2021-12-31ProductCollaborative Arrangement ATVTREM25,000,000USD0001714899-23-000049
    FY 2021Yearly · 2021-12-31ProductCollaborative Arrangement PTVPGRN5,000,000USD0001714899-23-000049
    FY 2021Yearly · 2021-12-31ProductLRRK2Product0USD0001714899-23-000049
    FY 2021Yearly · 2021-12-31ProductOption Services3,736,000USD0001714899-23-000049
    FY 2021Yearly · 2021-12-31ProductPeripheral Product15,000,000USD0001714899-23-000049
    FY 2021Yearly · 2021-12-31ProductRetained Activities0USD0001714899-23-000049
    Q3 2021Quarterly · 2021-09-30ProductCNSProgram License0USD0001714899-22-000144
    Q3 2021Quarterly · 2021-09-30ProductCollaboration Agreement Services4,425,000USD0001714899-22-000144
    Q3 2021Quarterly · 2021-09-30ProductOption Services860,000USD0001714899-22-000144
    Q3 2021Quarterly · 2021-09-30ProductPeripheral Product0USD0001714899-22-000144
    Q2 2021Quarterly · 2021-06-30ProductCNSProgram License0USD0001714899-22-000123
    Q2 2021Quarterly · 2021-06-30ProductCollaboration Agreement Services7,142,000USD0001714899-22-000123
    Q2 2021Quarterly · 2021-06-30ProductOption Services794,000USD0001714899-22-000123
    Q2 2021Quarterly · 2021-06-30ProductPeripheral Product15,000,000USD0001714899-22-000123
    FY 2020Yearly · 2020-12-31ProductCNSProgram License0USD0001714899-23-000049
    FY 2020Yearly · 2020-12-31ProductCollaboration Agreement Services27,155,000USD0001714899-23-000049
    FY 2020Yearly · 2020-12-31ProductCollaborative Arrangement ATVTREM20USD0001714899-23-000049
    FY 2020Yearly · 2020-12-31ProductCollaborative Arrangement PTVPGRN0USD0001714899-23-000049
    FY 2020Yearly · 2020-12-31ProductLRRK2Product306,545,000USD0001714899-23-000049
    FY 2020Yearly · 2020-12-31ProductOption Services892,000USD0001714899-23-000049
    FY 2020Yearly · 2020-12-31ProductPeripheral Product0USD0001714899-23-000049
    FY 2020Yearly · 2020-12-31ProductRetained Activities969,000USD0001714899-23-000049
    FY 2019Yearly · 2019-12-31ProductATVTREM2Services0USD0001714899-22-000058
    FY 2019Yearly · 2019-12-31ProductCollaboration Agreement Services5,926,000USD0001714899-22-000058
    FY 2019Yearly · 2019-12-31ProductLRRK2Product0USD0001714899-22-000058
    FY 2019Yearly · 2019-12-31ProductOption Services0USD0001714899-22-000058
    FY 2019Yearly · 2019-12-31ProductPeripheral Product10,000,000USD0001714899-22-000058
    FY 2019Yearly · 2019-12-31ProductPTVPGRNServices0USD0001714899-22-000058
    FY 2019Yearly · 2019-12-31ProductRetained Activities10,394,000USD0001714899-22-000058
    FY 2018Yearly · 2018-12-31ProductCNSProgram License73,932,000USD0001714899-21-000033
    FY 2018Yearly · 2018-12-31ProductLRRK2Product0USD0001714899-21-000033
    FY 2018Yearly · 2018-12-31ProductOption Services0USD0001714899-21-000033
    FY 2018Yearly · 2018-12-31ProductOther5,677,000USD0001714899-21-000033
    FY 2018Yearly · 2018-12-31ProductPeripheral Product47,148,000USD0001714899-21-000033
    FY 2018Yearly · 2018-12-31ProductRetained Activities2,343,000USD0001714899-21-000033

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.