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    CBIO

    CRESCENT BIOPHARMA, INC.

    Company overview

    Market capitalization
    $400.62M
    Employees
    55
    Latest publication
    2026-09-29
    About CRESCENT BIOPHARMA, INC.

    Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. for the development and commercialization of oncology therapeutics. The company was formerly known as GlycoMimetics, Inc. The company was founded in 2024 and is headquartered in Waltham, Massachusetts.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Revenue0USD1,039,000USD10,844,000USD———0USD—
    Research Development19,391,000USD17,903,000USD95,028,000USD20,347,000USD12,081,000USD10,627,000USD14,034,000USD1,715,347USD
    General And Administrative Expenses8,743,000USD7,865,000USD——————
    Total Operating Expenses28,134,000USD25,768,000USD102,337,000USD25,885,000USD21,030,000USD14,224,000USD17,191,000USD11,233,798USD
    Operating Income-26,364,000USD-24,729,000USD————-17,191,000USD-11,233,798USD
    Total Other Income Expense Net1,527,000USD1,446,000USD————-676,000USD1,409,322USD
    Interest Expense0USD0USD————852,000USD—
    Net Income-24,837,000USD-23,283,000USD-92,398,000USD-24,607,000USD-21,790,000USD-15,148,000USD-17,867,000USD-9,824,333USD
    Selling General Administrative—7,865,000USD————3,157,000USD4,006,000USD
    Income Before Tax—-23,283,000USD————-17,867,000USD-9,824,476USD
    Income Tax Expense—0USD2,000,000USD—————
    Net Income Applicable To Common Shares—-21,262,000USD——————
    Cost Of Revenue——————27,043USD8,130USD
    Gross Profit——————27,043USD-8,130USD
    Interest Income——————176,000USD—
    Net Interest Income——————-676,000USD—
    Tax Provision——————0USD—
    Net Income From Continuing Ops——————-17,867,000USD—
    Ebit——————-17,015,000USD-5,721,347USD
    Ebitda——————18,123,826USD-5,713,216USD
    Depreciation And Amortization——————35,138,826USD8,131USD
    Reconciled Depreciation——————0USD—
    Unclassified Operating Expenses———————5,512,451USD
    SourceDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosurePreliminaryDisclosurePreliminaryDisclosurePreliminaryDisclosurePreliminaryLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20172017-12-31 · USD
    Total Revenue10,844,000USD—10,000USD75,000USD1,159,767USD10,162,935USD——
    Research Development138,086,000USD28,060,542USD20,071,656USD28,390,879USD47,491,567USD44,929,198USD47,029,000USD24,100,092USD
    Selling General Administrative25,390,000USD16,324,566USD19,213,637USD19,087,000USD17,115,405USD16,743,127USD14,360,000USD9,832,188USD
    General And Administrative Expenses25,390,000USD—19,213,637USD—————
    Total Operating Expenses163,476,000USD49,897,519USD39,285,293USD47,478,322USD64,606,972USD61,672,325USD61,389,000USD33,668,739USD
    Operating Income-152,632,000USD-49,897,519USD-39,275,293USD-47,403,322USD-63,447,205USD-51,509,390USD-61,389,000USD-33,932,280USD
    Total Other Income Expense Net690,000USD1,373,930USD—714,963USD19,768USD482,487USD3,497,391USD651,212USD
    Interest Expense2,185,000USD852,000USD——————
    Income Before Tax-151,942,000USD-48,523,589USD—-46,688,359USD-63,427,437USD-51,026,903USD-57,892,000USD-33,281,068USD
    Income Tax Expense2,000,000USD—————-3,776,234USD—
    Net Income-153,942,000USD-48,523,406USD-36,899,420USD-46,688,802USD-63,427,437USD-51,026,903USD-54,115,766USD-33,281,068USD
    Net Income Applicable To Common Shares-133,446,000USD———————
    Cost Of Revenue—35,174USD—1,032,156USD—951,599USD899,302USD263,541USD
    Gross Profit—-35,174USD—75,000USD1,159,767USD10,162,935USD-899,302USD-263,541USD
    Unclassified Operating Expenses—5,512,411USD——————
    Ebit—-44,209,108USD—-47,402,879USD-63,447,205USD-51,509,390USD-57,891,911USD-33,932,280USD
    Ebitda—-44,173,934USD—-47,195,734USD-63,182,605USD-51,238,636USD-56,992,609USD-33,668,739USD
    Depreciation And Amortization—35,174USD—207,145USD264,600USD270,754USD899,302USD263,541USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets182,758,000USD199,130,000USD240,293,000USD138,269,000USD157,433,000USD5,992,180USD11,091,454USD15,698,141USD
    Cash And Equivalents171,593,000USD189,163,000USD213,192,000USD133,265,000USD—5,614,186USD10,720,178USD14,391,664USD
    Total Current Assets179,006,000USD195,563,000USD236,655,000USD134,563,000USD154,227,000USD5,992,180USD11,091,454USD15,645,821USD
    Other Current Assets7,413,000USD6,400,000USD5,463,000USD1,298,000USD1,582,000USD377,994USD371,276USD1,254,157USD
    Other Non Current Assets1,498,000USD1,159,000USD1,216,000USD1,253,000USD1,300,000USD———
    Total Liabilities19,503,000USD15,283,000USD37,281,000USD21,628,000USD18,179,000USD2,616,926USD5,777,892USD4,321,856USD
    Total Current Liabilities18,537,000USD14,193,000USD36,072,000USD20,304,000USD16,746,000USD2,616,926USD5,777,892USD4,321,856USD
    Total Stockholder Equity163,255,000USD183,847,000USD203,012,000USD116,641,000USD139,254,000USD3,375,254USD5,313,562USD11,376,285USD
    Total Equity Including Noncontrolling Interest163,255,000USD183,847,000USD203,012,000USD116,641,000USD139,254,000USD3,375,254USD5,313,562USD11,376,285USD
    Deferred Revenue3,117,000USD3,117,000USD4,156,000USD—————
    Net Receivables0USD0USD18,000,000USD—————
    Property Plant Equipment Net2,147,000USD2,301,000USD2,315,000USD2,346,000USD1,800,000USD———
    Short Term Debt471,000USD453,000USD435,000USD417,000USD211,000USD—66,844USD262,133USD
    Common Stock28,000USD28,000USD28,000USD14,000USD14,000USD64,532USD64,484USD64,484USD
    Retained Earnings-219,929,000USD-195,092,000USD-171,809,000USD-79,412,000USD-54,805,000USD-496,708,106USD-494,364,370USD-487,141,618USD
    Other Current Liabilities—4,433,000USD16,344,000USD8,965,000USD7,608,000USD2,512,255USD5,381,744USD3,477,929USD
    Accounts Payable—————104,671USD329,304USD581,794USD
    SourceDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinal

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Assets240,293,000USD11,091,454USD45,316,475USD51,810,589USD94,346,648USD142,832,169USD167,969,679USD214,839,000USD
    Cash And Equivalents213,192,000USD10,720,178USD41,792,830USD—————
    Total Current Assets236,655,000USD11,091,454USD43,790,734USD50,714,705USD90,788,694USD138,273,345USD162,527,763USD212,269,119USD
    Other Current Assets5,463,000USD371,276USD1,997,904USD2,700,070USD532,457USD1,236,179USD4,140,369USD1,938,402USD
    Other Non Current Assets1,216,000USD———————
    Total Liabilities37,281,000USD5,777,892USD6,902,074USD—————
    Total Current Liabilities36,072,000USD5,777,892USD6,835,230USD8,880,752USD11,824,390USD12,428,369USD10,950,576USD8,763,154USD
    Other Current Liabilities16,344,000USD5,381,744USD5,225,557USD—————
    Total Stockholder Equity203,012,000USD5,313,562USD38,414,401USD42,929,837USD81,603,651USD128,219,456USD154,200,587USD205,464,000USD
    Total Equity Including Noncontrolling Interest203,012,000USD5,313,562USD38,414,401USD—————
    Deferred Revenue4,156,000USD———————
    Net Receivables18,000,000USD——144,016USD1,347USD2,149USD185,953USD413,122USD
    Property Plant Equipment Net2,315,000USD—767,828USD751,174USD1,945,027USD2,945,897USD3,828,989USD957,226USD
    Short Term Debt435,000USD66,844USD741,558USD918,555USD1,001,407USD898,549USD804,126USD—
    Common Stock28,000USD64,484USD64,394USD54,378USD52,314USD49,018USD43,465USD43,159USD
    Retained Earnings-171,809,000USD-494,364,370USD-456,485,212USD-419,585,792USD-372,896,990USD-309,469,553USD-258,442,650USD-200,550,739USD
    Accounts Payable—329,304USD868,115USD970,191USD2,107,615USD2,089,939USD1,435,660USD2,663,579USD
    Total Liab———8,880,752USD12,742,997USD14,612,713USD13,769,092USD9,375,000USD
    Other Current Liab———6,992,006USD8,715,368USD9,439,881USD8,710,790USD6,099,575USD
    Cash———47,870,619USD90,254,890USD137,035,017USD158,201,441USD209,918,000USD
    Cash And Short Term Investments———47,870,619USD90,254,890USD137,035,017USD158,201,441USD209,918,000USD
    Net Debt———-46,952,064USD-88,334,876USD-134,216,453USD-154,578,799USD-209,918,000USD
    Short Long Term Debt Total———918,555USD1,920,014USD2,818,564USD3,622,642USD—
    Common Stock Shares Outstanding———52,531,173shares51,453,294shares45,721,139shares43,254,782shares41,044,621shares
    Non Current Assets Total———1,095,884USD3,557,954USD4,558,824USD5,441,916USD2,570,153USD
    Non Currrent Assets Other———344,710USD1,612,927USD1,612,927USD1,612,927USD1,612,927USD
    Unclassified Equity———462,461,251USD454,448,327USD437,639,991USD412,599,772USD405,971,580USD
    Non Current Liabilities Total————918,607USD2,184,344USD2,818,516USD611,623USD
    Unclassified Non Current Liabilities—————2,184,344USD2,818,516USD—
    Other Assets———————-272USD
    Inventory———————-405USD
    SourceDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ2 20242024-06-30 · USDQ1 20242024-03-31 · USDQ4 20232023-12-31 · USD
    Depreciation64,000USD54,000USD28,000USD2,000USD—12,423USD14,620USD23,297USD
    Stock Based Compensation4,113,000USD4,745,000USD1,986,000USD5,340,000USD405,428USD1,246,697USD1,192,080USD944,371USD
    Change To Account Receivables18,000,000USD-4,894,000USD——————
    Change To Liabilities-3,456,000USD———-3,094,122USD—-1,430,298USD—
    Change In Working Capital17,120,000USD-19,237,000USD4,960,000USD-2,160,000USD-231,351USD-231,137USD-100,610USD299,866USD
    Operating Cash Flow-8,937,000USD———-5,105,992USD—-10,508,829USD—
    Capital Expenditures-147,000USD-72,193,000USD-586,000USD-140,000USD—-2,535USD-7,439USD-803USD
    Unclassified Investing Cash Flow-8,000,000USD72,000,000USD——————
    Investing Cash Flow-8,147,000USD—————-7,439USD—
    Financing Cash Flow-6,945,000USD—————4,898USD—
    Change In Cash-24,029,000USD79,927,000USD-19,379,000USD130,322,000USD-5,105,992USD-8,895,408USD-10,511,370USD-7,614,799USD
    End Cash Flow189,270,000USD———5,614,186USD—31,281,460USD—
    Net Income—-92,397,000USD-24,607,000USD-21,790,000USD—-10,095,406USD—-9,079,000USD
    Other Non Cash Items—80,095,000USD94,000USD2,206,000USD—174,048USD—1,140,840USD
    Change To Inventory—72,000USD——————
    Total Cash From Operating Activities—-26,740,000USD-17,539,000USD-16,402,000USD—-8,893,375USD—-7,614,997USD
    Free Cash Flow—-98,933,000USD-18,125,000USD-16,542,000USD—-8,895,910USD—-7,615,800USD
    Total Cashflows From Investing Activities—-72,193,000USD-586,000USD-140,000USD—-2,533USD—-801USD
    Total Cash From Financing Activities—178,860,000USD-1,254,000USD146,864,000USD—500USD—999USD
    Sale Purchase Of Stock—177,000USD—-177,000USD————
    Issuance Of Capital Stock—178,860,000USD-1,254,000USD—————
    Begin Period Cash Flow—133,372,000USD152,751,000USD22,429,000USD—31,281,460USD—49,407,629USD
    End Period Cash Flow—213,299,000USD133,372,000USD152,751,000USD—22,386,052USD—41,792,830USD
    Other Cashflows From Investing Activities—-72,000,000USD——————
    Other Cashflows From Financing Activities—-177,000USD177,000USD146,864,000USD————
    Unclassified Financing Cash Flow—178,860,000USD——————
    Common Stock Issuance——————4,898USD—
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyDisclosureDeterministicFinalLegacy providerLegacyDisclosureDeterministicFinalLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20182018-12-31 · USDFY 20172017-12-31 · USD
    Depreciation84,000USD35,174USD153,301USD207,145USD264,600USD270,754USD275,123USD263,541USD
    Stock Based Compensation13,300,000USD4,697,546USD3,524,476USD3,857,580USD6,087,286USD6,901,758USD4,587,098USD3,760,802USD
    Deferred Income Tax0USD———————
    Change To Account Receivables-18,000,000USD———————
    Change To Liabilities5,363,000USD-382,624USD-1,868,525USD—————
    Change In Working Capital-22,853,000USD1,140,137USD744,106USD-4,661,920USD-1,165,192USD3,931,615USD80,114USD-511,636USD
    Operating Cash Flow-71,532,000USD-31,098,078USD-34,879,903USD—————
    Capital Expenditures-919,000USD-9,972USD-21,394USD-84,191USD-14,943USD-68,507USD-125,618USD-294,107USD
    Unclassified Investing Cash Flow-72,000,000USD30,000USD——————
    Investing Cash Flow-72,919,000USD20,028USD-21,394USD—————
    Financing Cash Flow322,984,000USD5,398USD28,823,508USD—————
    Change In Cash178,533,000USD-31,072,652USD-6,077,789USD-42,384,271USD-46,780,127USD-21,166,424USD85,992,857USD83,883,097USD
    End Cash Flow213,299,000USD10,720,178USD41,792,830USD—————
    Common Stock Issuance—5,398USD116,497USD—————
    Unclassified Financing Cash Flow——28,707,011USD—10,699,317USD17,824,717USD128,425,080USD113,572,189USD
    Net Income———-46,688,802USD-63,427,437USD-51,026,903USD-48,273,633USD-33,281,068USD
    Other Non Cash Items———828,509USD749,039USD680,845USD168USD—
    Total Cash From Operating Activities———-46,457,488USD-57,489,530USD-39,241,931USD-43,331,130USD-29,768,361USD
    Free Cash Flow———-46,541,679USD-57,504,473USD-39,310,438USD-43,456,748USD-30,062,468USD
    Total Cashflows From Investing Activities———-84,191USD-14,943USD-68,507USD-125,618USD-294,107USD
    Total Cash From Financing Activities———4,157,408USD10,724,346USD18,144,014USD129,449,605USD113,945,565USD
    Begin Period Cash Flow———90,254,890USD137,035,017USD158,201,441USD123,924,738USD40,041,641USD
    End Period Cash Flow———47,870,619USD90,254,890USD137,035,017USD209,917,595USD123,924,738USD
    Other Cashflows From Financing Activities————25,029USD319,297USD1,024,525USD373,376USD
    SourceDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow YTD

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Depreciation30,000USD2,000USD35,174USD27,043USD
    Stock Based Compensation8,555,000USD6,569,000USD3,537,517USD2,399,402USD
    Change In Working Capital-725,000USD-1,056,000USD457,426USD609,099USD
    Operating Cash Flow-44,792,000USD-27,253,000USD-27,396,592USD-19,402,204USD
    Capital Expenditures-726,000USD-140,000USD-9,972USD-9,972USD
    Investing Cash Flow-726,000USD-140,000USD-9,972USD-9,972USD
    Financing Cash Flow144,124,000USD145,378,000USD5,398USD5,398USD
    Change In Cash98,606,000USD117,985,000USD-27,401,166USD-19,406,778USD
    End Cash Flow133,372,000USD152,751,000USD14,391,664USD22,386,052USD
    Change To Liabilities——-2,033,949USD-2,186,131USD
    Common Stock Issuance——5,398USD5,398USD
    SourceDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinalDisclosureDeterministicFinal

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    No revenue breakdown is currently published for this company.

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.