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    BCRX

    BIOCRYST PHARMACEUTICALS INC

    Company overview

    Market capitalization
    $2.16B
    Employees
    435
    Latest publication
    2026-09-29
    About BIOCRYST PHARMACEUTICALS INC

    BioCryst Pharmaceuticals, Inc., a biotechnology company, developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated and seasonal influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat HAE. It is also developing BCX17725, a protein therapeutic for netherton syndrome which is in phase 1; Avoralstat, an ocular plasma kallikrein inhibitor for diabetic macular edema that is in Phase 1; Navenibart, a monoclonal antibody plasma kallikrein inhibitor for HAE which is in Phase 3; BCX17725, an investigational protein therapeutic KLK5 inhibitor for the treatment of netherton syndrome that is in phase 1 clinical trial; STAR-0310, a monoclonal antibody OX40 antagonist for the treatment of atopic dermatitis which is in Phase 1a trial. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd., Shionogi & Co., Ltd., and Green Cross Corporation; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USDQ2 20232023-06-30 · USDQ1 20232023-03-31 · USD
    Total Revenue406,555,000USD159,395,000USD163,353,000USD145,534,000USD117,085,000USD109,332,000USD82,491,000USD68,778,000USD
    Cost Of Revenue9,916,000USD2,522,000USD2,798,000USD4,568,000USD3,228,000USD1,699,000USD950,000USD938,000USD
    Gross Profit396,639,000USD156,873,000USD160,555,000USD140,966,000USD113,857,000USD107,633,000USD81,541,000USD67,840,000USD
    Research Development41,202,000USD44,268,000USD43,386,000USD37,270,000USD41,081,000USD37,623,000USD51,247,000USD48,388,000USD
    Selling General Administrative95,781,000USD83,014,000USD87,383,000USD82,469,000USD65,084,000USD61,214,000USD47,707,000USD43,820,000USD
    Total Operating Expenses136,648,000USD127,282,000USD130,769,000USD119,739,000USD106,165,000USD98,872,000USD102,244,000USD96,255,000USD
    Operating Income260,385,000USD29,591,000USD29,786,000USD21,227,000USD7,692,000USD8,761,000USD-20,703,000USD-28,415,000USD
    Interest Income2,890,000USD2,238,000USD2,516,000USD3,024,000USD3,591,000USD3,554,000USD3,750,000USD3,378,000USD
    Interest Expense14,135,000USD19,661,000USD21,582,000USD23,494,000USD24,828,000USD24,733,000USD28,915,000USD27,396,000USD
    Net Interest Income-11,245,000USD-17,423,000USD-19,066,000USD-20,470,000USD-21,237,000USD-21,179,000USD-25,165,000USD-24,018,000USD
    Income Before Tax248,017,000USD12,130,000USD6,486,000USD758,000USD-13,447,000USD-12,502,000USD-74,586,000USD-52,662,000USD
    Income Tax Expense2,172,000USD-769,000USD1,401,000USD726,000USD586,000USD172,000USD740,000USD671,000USD
    Tax Provision2,172,000USD-769,000USD1,401,000USD726,000USD586,000USD172,000USD740,000USD671,000USD
    Net Income245,845,000USD12,899,000USD5,085,000USD32,000USD-14,033,000USD-12,674,000USD-75,326,000USD-53,333,000USD
    Net Income From Continuing Ops245,845,000USD12,899,000USD5,085,000USD32,000USD-14,033,000USD-12,674,000USD-75,326,000USD-53,333,000USD
    Ebit262,152,000USD31,791,000USD28,068,000USD24,252,000USD11,381,000USD12,231,000USD-45,671,000USD-25,266,000USD
    Ebitda266,196,000USD32,126,000USD28,397,000USD24,583,000USD11,692,000USD12,551,000USD-45,264,000USD-24,861,000USD
    Depreciation And Amortization4,044,000USD335,000USD329,000USD331,000USD311,000USD320,000USD407,000USD405,000USD
    Reconciled Depreciation394,000USD335,000USD329,000USD331,000USD311,000USD320,000USD407,000USD405,000USD
    Total Other Income Expense Net-12,368,000USD-17,461,000USD-23,300,000USD-20,469,000USD-21,139,000USD-21,263,000USD-53,883,000USD-24,247,000USD
    Selling And Marketing Expenses——————3,290,000USD4,047,000USD
    Non Operating Income Net Other——————-28,718,000USD-229,000USD
    Net Income Applicable To Common Shares——————-75,326,000USD-53,333,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20082008-12-31 · USDFY 20072007-12-31 · USDFY 20062006-12-31 · USDFY 20032003-12-31 · USDFY 20012001-12-31 · USDFY 20002000-12-31 · USD
    Total Revenue874,837,000USD450,712,000USD56,561,369USD71,237,901USD6,211,936USD1,634,000USD11,157,634USD3,315,594USD
    Cost Of Revenue19,075,000USD12,485,000USD46,811,000USD71,951,000USD32,863,000USD2,899,000USD15,094,000USD12,479,000USD
    Gross Profit855,762,000USD438,227,000USD56,561,369USD71,237,901USD6,211,936USD1,634,000USD11,157,634USD3,315,594USD
    Research Development166,126,000USD174,638,000USD73,326,634USD94,051,996USD47,083,372USD11,522,000USD13,091,057USD9,590,352USD
    Selling General Administrative348,647,000USD252,503,000USD10,399,227USD9,465,962USD6,108,373USD2,812,000USD3,052,089USD3,557,256USD
    Total Operating Expenses514,773,000USD440,770,000USD83,725,861USD103,517,958USD53,191,745USD14,334,000USD16,143,146USD13,147,608USD
    Operating Income340,989,000USD-2,543,000USD-27,164,492USD-32,280,057USD-46,979,809USD-12,700,000USD-4,985,512USD-9,832,014USD
    Interest Income10,668,000USD14,746,000USD——————
    Interest Expense78,872,000USD98,516,000USD0USD0USD0USD0USD0USD0USD
    Net Interest Income-68,204,000USD-83,770,000USD——————
    Income Before Tax267,391,000USD-86,954,000USD-24,732,000USD-29,055,000USD-26,098,768,000USD-12,700,083,000USD-4,985,976,000USD-11,577,842,000USD
    Income Tax Expense3,530,000USD1,927,000USD-430USD524USD-26,055,150,147USD-12,687,383,000USD-4,980,990,024USD-11,566,264,158USD
    Tax Provision3,530,000USD1,927,000USD——————
    Net Income263,861,000USD-88,881,000USD-24,731,570USD-29,055,524USD-43,617,853USD-12,700,000USD-4,985,976USD-11,577,842USD
    Net Income From Continuing Ops263,861,000USD-88,881,000USD——————
    Ebit346,263,000USD11,562,000USD-24,731,570USD-29,055,524USD-43,617,853USD-13,679,819USD-4,985,512USD-9,832,014USD
    Ebitda347,652,000USD12,808,000USD-23,105,692USD-27,685,811USD-42,796,658USD-12,578,819USD-3,936,077USD-9,162,800USD
    Depreciation And Amortization1,389,000USD1,246,000USD1,625,878USD1,369,713USD821,195USD1,101,000USD1,049,435USD669,214USD
    Reconciled Depreciation1,389,000USD1,246,000USD——————
    Total Other Income Expense Net-73,598,000USD-84,411,000USD2,432,492USD3,224,533USD-26,051,788,191USD-12,686,402,668USD-4,980,990,488USD-11,568,009,986USD
    Selling And Marketing Expenses—13,566,000USD——————
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets557,851,000USD465,052,000USD514,158,000USD446,424,000USD457,188,000USD480,047,000USD490,420,000USD491,254,000USD
    Cash And Equivalents154,972,000USD———————
    Cash And Short Term Investments352,573,000USD239,254,000USD274,747,000USD212,873,000USD260,038,000USD295,383,000USD321,060,000USD330,826,000USD
    Short Term Investments197,601,000USD66,809,000USD185,011,000USD128,794,999USD172,005,000USD189,902,000USD216,137,000USD233,172,000USD
    Long Term Investments0USD20,569,000USD61,164,000USD39,669,000USD10,101,000USD20,548,000USD20,323,000USD19,426,000USD
    Total Current Assets484,683,000USD373,625,000USD404,346,000USD355,684,000USD398,462,000USD409,977,000USD421,968,000USD427,125,000USD
    Other Current Assets14,818,000USD19,114,000USD17,383,000USD46,253,999USD42,203,000USD14,327,000USD13,752,000USD16,281,000USD
    Other Non Current Assets19,557,000USD———————
    Total Liabilities1,012,140,000USD———————
    Total Current Liabilities208,846,000USD195,391,000USD196,066,000USD190,237,000USD177,160,000USD139,855,000USD160,384,000USD153,567,000USD
    Other Current Liabilities121,895,000USD———————
    Total Stockholder Equity-454,289,000USD-553,843,000USD-119,153,000USD-387,889,000USD-421,594,000USD-451,927,000USD-475,934,000USD-468,563,000USD
    Total Equity Including Noncontrolling Interest-454,289,000USD———————
    Long Term Debt395,400,000USD802,378,000USD427,233,000USD633,473,000USD690,636,000USD782,026,000USD795,922,000USD796,108,000USD
    Deferred Revenue12,320,000USD———————
    Deferred Revenue Non Current13,461,000USD———————
    Net Receivables110,757,000USD109,272,000USD106,818,000USD91,325,000USD91,177,000USD93,394,000USD79,069,000USD72,456,000USD
    Inventory6,056,000USD5,985,000USD5,398,000USD5,232,000USD5,044,000USD6,873,000USD8,087,000USD7,562,000USD
    Property Plant Equipment Net9,058,000USD22,985,000USD18,986,000USD19,236,000USD20,003,000USD19,575,000USD19,785,000USD23,070,000USD
    Accounts Payable11,459,000USD10,958,000USD15,826,000USD5,567,000USD8,589,000USD10,049,000USD11,644,000USD13,482,000USD
    Short Term Debt1,912,000USD43,410,000USD1,629,000USD39,469,000USD2,008,000USD37,171,000USD35,448,000USD35,888,000USD
    Common Stock2,553,000USD2,540,000USD2,131,000USD2,105,000USD2,099,000USD2,092,000USD2,085,000USD2,071,000USD
    Retained Earnings-2,149,596,000USD-2,227,991,000USD-1,506,179,000USD-1,752,024,000USD-1,764,923,000USD-1,770,008,000USD-1,770,040,000USD-1,743,245,000USD
    Accumulated Other Comprehensive Income-528,000USD-368,000USD38,000USD1,139,999USD1,646,000USD1,132,000USD921,000USD2,293,000USD
    Total Liab—1,018,895,000USD633,311,000USD834,313,000USD878,782,000USD931,974,000USD966,354,000USD959,817,000USD
    Other Current Liab—135,614,000USD178,611,000USD145,201,000USD166,563,000USD92,635,000USD113,292,000USD104,197,000USD
    Capital Stock—2,540,000USD2,131,000USD2,105,000USD2,099,000USD2,092,000USD2,085,000USD2,071,000USD
    Cash—172,445,000USD89,736,000USD84,078,000USD88,033,000USD105,481,000USD104,923,000USD97,654,000USD
    Current Deferred Revenue—5,409,000USD——————
    Net Debt—685,638,000USD349,138,000USD599,031,000USD615,143,000USD723,809,000USD736,495,000USD744,484,000USD
    Short Long Term Debt Total—858,083,000USD438,874,000USD683,109,000USD703,176,000USD829,290,000USD841,418,000USD842,138,000USD
    Property Plant Equipment Gross—22,985,000USD28,380,000USD19,236,000USD20,003,000USD19,575,000USD32,134,000USD—
    Common Stock Shares Outstanding—242,258,000shares219,263,000shares219,885,000shares219,886,000shares215,261,000shares207,381,000shares206,905,000shares
    Non Current Assets Total—91,427,000USD109,812,000USD90,740,000USD58,726,000USD70,070,000USD68,452,000USD64,129,000USD
    Non Current Liabilities Total—823,504,000USD437,245,000USD644,076,000USD701,622,000USD792,119,000USD805,970,000USD806,250,000USD
    Non Currrent Assets Other—46,940,000USD29,662,000USD31,835,000USD28,622,000USD28,547,000USD26,944,000USD21,633,000USD
    Net Working Capital—178,234,000USD208,280,000USD165,447,000USD221,302,000USD270,122,000USD261,584,000USD273,558,000USD
    Unclassified Non Current Liabilities—21,126,000USD10,012,000USD10,603,000USD10,986,000USD10,093,000USD10,048,000USD10,142,000USD
    Unclassified Equity—1,669,436,000USD1,382,726,000USD1,358,785,001USD1,337,485,000USD1,312,765,000USD1,289,015,000USD1,268,247,000USD
    Other Assets————95,872,000USD71,013,000USD——
    Unclassified Non Current Assets————-95,872,000USD-69,613,000USD1,400,000USD—
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Assets514,158,000USD490,420,000USD516,960,000USD550,000,000USD588,151,000USD334,715,000USD175,282,000USD146,841,000USD
    Other Current Assets17,383,000USD13,752,000USD21,346,000USD14,058,000USD13,331,000USD5,528,000USD5,973,000USD3,943,000USD
    Total Liab633,311,000USD966,354,000USD972,488,000USD844,597,000USD695,137,000USD353,977,000USD137,030,000USD97,606,000USD
    Total Stockholder Equity-119,153,000USD-475,934,000USD-455,528,000USD-294,597,000USD-106,986,000USD-19,262,000USD38,252,000USD-731,969,000USD
    Other Current Liab178,611,000USD113,292,000USD126,447,000USD87,155,000USD70,048,000USD55,612,000USD36,202,000USD27,688,000USD
    Common Stock2,131,000USD2,085,000USD2,058,000USD1,879,000USD1,843,000USD1,769,000USD1,541,000USD1,101,000USD
    Capital Stock2,131,000USD2,085,000USD2,058,000USD1,879,000USD1,843,000USD1,769,000USD1,541,000USD1,101,000USD
    Retained Earnings-1,506,179,000USD-1,770,040,000USD-1,681,159,000USD-1,454,620,000USD-1,207,504,000USD-1,023,442,000USD-840,628,000USD-731,969,000USD
    Cash89,736,000USD104,923,000USD110,643,000USD304,767,000USD504,389,000USD272,127,000USD114,172,000USD26,731,000USD
    Cash And Short Term Investments274,747,000USD321,060,000USD388,987,000USD424,310,000USD507,601,000USD300,366,000USD136,226,000USD126,843,000USD
    Total Current Assets404,346,000USD421,968,000USD495,966,000USD516,500,000USD566,136,000USD323,800,000USD164,345,000USD114,352,000USD
    Total Current Liabilities196,066,000USD160,384,000USD149,988,000USD105,514,000USD103,718,000USD105,654,000USD92,335,000USD69,477,000USD
    Net Debt349,138,000USD736,495,000USD714,505,000USD436,685,000USD88,849,000USD-147,410,000USD-29,519,000USD35,092,000USD
    Short Term Debt1,629,000USD35,448,000USD2,648,000USD2,369,000USD1,819,000USD31,179,000USD39,958,000USD33,748,000USD
    Short Long Term Debt Total438,874,000USD841,418,000USD825,148,000USD741,452,000USD593,238,000USD150,914,000USD84,653,000USD61,823,000USD
    Long Term Debt427,233,000USD795,922,000USD811,265,000USD733,279,000USD585,457,000USD119,735,000USD41,289,000USD25,372,000USD
    Long Term Investments61,164,000USD20,323,000USD0USD18,077,000USD6,829,000USD—0USD22,376,000USD
    Short Term Investments185,011,000USD216,137,000USD278,344,000USD119,543,000USD3,212,000USD28,239,000USD22,054,000USD77,736,000USD
    Net Receivables106,818,000USD79,069,000USD56,950,000USD50,599,000USD29,413,000USD8,646,000USD22,146,000USD4,293,000USD
    Inventory5,398,000USD8,087,000USD28,683,000USD27,533,000USD15,791,000USD7,039,000USD1,551,000USD1,649,000USD
    Accounts Payable15,826,000USD11,644,000USD20,893,000USD14,356,000USD27,808,000USD18,713,000USD13,988,000USD7,769,000USD
    Property Plant Equipment Net18,986,000USD19,785,000USD20,914,000USD8,617,000USD15,186,000USD7,113,000USD7,347,000USD9,135,000USD
    Property Plant Equipment Gross28,380,000USD32,134,000USD19,120,000USD24,973,000USD8,714,000USD7,113,000USD7,347,000USD9,135,000USD
    Accumulated Other Comprehensive Income38,000USD921,000USD1,337,000USD26,000USD177,000USD3,000USD39,000USD-297,000USD
    Common Stock Shares Outstanding218,581,000shares206,696,000shares192,198,000shares185,908,000shares179,117,000shares167,267,000shares115,600,000shares103,185,000shares
    Non Current Assets Total109,812,000USD68,452,000USD20,994,000USD33,500,000USD22,015,000USD10,915,000USD10,937,000USD32,489,000USD
    Non Current Liabilities Total437,245,000USD805,970,000USD822,500,000USD739,083,000USD591,419,000USD248,323,000USD44,695,000USD28,129,000USD
    Non Currrent Assets Other29,662,000USD26,944,000USD80,000USD6,806,000USD6,472,000USD3,802,000USD3,590,000USD978,000USD
    Net Working Capital208,280,000USD261,584,000USD345,978,000USD410,986,000USD462,418,000USD218,146,000USD72,010,000USD44,875,000USD
    Unclassified Non Current Liabilities10,012,000USD10,048,000USD11,235,000USD—5,962,000USD128,588,000USD3,406,000USD2,649,000USD
    Unclassified Equity1,382,726,000USD1,289,015,000USD1,220,178,000USD1,156,239,000USD1,096,655,000USD1,000,639,000USD875,759,000USD—
    Unclassified Non Current Assets—1,400,000USD—-550,000,000USD-594,622,456USD———
    Other Assets———550,000,000USD588,150,456USD——978,000USD
    Current Deferred Revenue———1,224,000USD1,421,000USD150,000USD2,120,000USD221,000USD
    Net Tangible Assets———-294,597,000USD-147,044,000USD109,326,000USD82,947,000USD77,310,000USD
    Unclassified Current Liabilities————2,622,000USD-30,000,000USD-38,514,000USD-33,650,000USD
    Short Long Term Debt—————30,000,000USD38,581,000USD33,701,000USD
    Deferred Long Term Liab———————54,000USD
    Other Liab———————54,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USDQ1 20242024-03-31 · USD
    Net Income-721,812,000USD12,899,000USD5,085,000USD32,000USD-26,795,000USD-14,033,000USD-12,674,000USD-35,379,000USD
    Depreciation1,061,000USD335,000USD329,000USD331,000USD309,000USD311,000USD320,000USD306,000USD
    Stock Based Compensation16,027,000USD18,601,000USD21,304,000USD21,368,000USD21,339,000USD17,249,000USD13,173,000USD13,652,000USD
    Other Non Cash Items713,991,000USD11,159,000USD12,207,000USD12,884,000USD11,265,000USD13,851,000USD16,109,000USD16,259,000USD
    Change To Account Receivables-474,000USD-17,000USD-7,308,000USD-13,987,000USD-7,296,000USD-3,317,000USD-8,246,000USD-3,839,000USD
    Change To Inventory-4,847,000USD-1,692,000USD1,438,000USD-870,000USD-2,163,000USD-1,520,000USD739,000USD-1,220,000USD
    Change In Working Capital-71,403,000USD-1,370,000USD2,377,000USD-62,132,000USD-11,331,000USD-9,133,000USD-18,296,000USD-48,522,000USD
    Total Cash From Operating Activities-62,136,000USD41,624,000USD41,302,000USD-27,517,000USD-5,213,000USD8,245,000USD-1,368,000USD-53,684,000USD
    Capital Expenditures-403,000USD-1,344,000USD-179,000USD-143,000USD-675,000USD-59,000USD-155,000USD-235,000USD
    Free Cash Flow-62,539,000USD40,280,000USD41,123,000USD-27,660,000USD-5,888,000USD8,186,000USD-1,523,000USD-53,919,000USD
    Investments221,235,000USD13,572,000USD29,127,000USD27,095,000USD17,797,000USD8,489,000USD-2,449,000USD28,756,000USD
    Total Cashflows From Investing Activities-268,648,000USD13,572,000USD29,127,000USD27,095,000USD17,797,000USD8,489,000USD-2,449,000USD28,756,000USD
    Net Borrowings399,655,000USD-46,852,000USD-70,044,000USD-516,000USD-356,000USD-556,000USD——
    Total Cash From Financing Activities412,897,000USD-58,814,000USD-73,686,000USD529,000USD-4,021,000USD1,274,000USD-1,966,000USD-1,048,000USD
    Issuance Of Capital Stock33,000USD21,000USD9,000USD6,000USD5,000USD6,000USD12,000USD11,000USD
    Change In Cash82,508,000USD-3,868,000USD-16,956,000USD558,000USD7,259,000USD18,859,000USD-5,926,000USD-26,316,000USD
    Begin Period Cash Flow89,937,000USD88,525,000USD106,881,000USD106,323,000USD99,064,000USD80,205,000USD86,131,000USD112,447,000USD
    End Period Cash Flow172,445,000USD84,657,000USD89,925,000USD106,881,000USD106,323,000USD99,064,000USD80,205,000USD86,131,000USD
    Other Cashflows From Investing Activities-403,000USD550,000USD—-143,000USD—-449,000USD-2,294,000USD-235,000USD
    Other Cashflows From Financing Activities-1,187,000USD-14,630,000USD-3,651,000USD1,039,000USD-3,670,000USD1,824,000USD-1,576,000USD-669,000USD
    Unclassified Investing Cash Flow-489,077,000USD—————2,449,000USD—
    Unclassified Financing Cash Flow14,396,000USD2,647,000USD——————
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Net Income263,861,000USD-88,881,000USD-226,539,000USD-247,116,000USD-184,062,000USD-182,814,000USD-108,897,000USD-101,252,000USD
    Depreciation1,389,000USD1,246,000USD1,655,000USD1,437,000USD777,000USD748,000USD724,000USD770,000USD
    Stock Based Compensation85,066,000USD65,413,000USD55,615,000USD44,701,000USD34,640,000USD14,794,000USD17,719,000USD9,396,000USD
    Other Non Cash Items36,462,000USD57,484,000USD106,529,000USD98,073,000USD-1,636,000USD17,975,000USD1,742,000USD885,000USD
    Change To Account Receivables-36,806,000USD-22,698,000USD-6,095,000USD-21,470,000USD-20,817,000USD13,903,000USD-17,853,000USD568,000USD
    Change To Inventory-1,639,000USD-4,164,000USD-1,450,000USD-12,423,000USD-8,767,000USD-7,039,000USD1,649,000USD-1,649,000USD
    Change In Working Capital-56,898,000USD-87,282,000USD-32,401,000USD-58,945,000USD8,124,000USD26,875,000USD-872,000USD-3,530,000USD
    Total Cash From Operating Activities329,880,000USD-52,020,000USD-95,141,000USD-161,850,000USD-142,157,000USD-137,216,000USD-89,584,000USD-92,565,000USD
    Capital Expenditures-2,468,000USD-1,124,000USD-2,168,000USD-1,351,000USD-2,385,000USD-514,000USD-343,000USD-366,000USD
    Free Cash Flow327,412,000USD-53,144,000USD-97,309,000USD-163,201,000USD-144,542,000USD-137,730,000USD-89,927,000USD-92,931,000USD
    Investments-5,593,000USD52,593,000USD-25,810,000USD-128,238,000USD18,189,000USD-6,343,000USD78,277,000USD5,134,000USD
    Total Cashflows From Investing Activities-13,694,000USD52,593,000USD-131,498,000USD-128,238,000USD15,804,000USD-6,856,000USD77,934,000USD4,768,000USD
    Net Borrowings-301,989,000USD-1,704,000USD58,383,000USD73,072,000USD293,874,000USD67,447,000USD19,477,000USD6,328,000USD
    Total Cash From Financing Activities-332,442,000USD-5,761,000USD32,485,000USD88,027,000USD359,668,000USD302,697,000USD99,098,000USD62,504,000USD
    Issuance Of Capital Stock59,000USD34,000USD342,000USD190,000USD50,000,000USD93,279,000USD58,500,000USD53,400,000USD
    Change In Cash-103,322,000USD-6,124,000USD-193,792,000USD-201,495,000USD233,386,000USD158,625,000USD87,448,000USD-25,293,000USD
    Begin Period Cash Flow104,923,000USD112,447,000USD306,239,000USD507,734,000USD274,348,000USD115,723,000USD28,275,000USD53,568,000USD
    End Period Cash Flow1,601,000USD106,323,000USD112,447,000USD306,239,000USD507,734,000USD274,348,000USD115,723,000USD28,275,000USD
    Other Cashflows From Investing Activities550,000USD-1,124,000USD1USD-1,351,000USD-2,385,000USD1,000USD-366,000USD-366,000USD
    Other Cashflows From Financing Activities-8,847,000USD-4,091,000USD-26,240,000USD14,765,000USD15,734,000USD124,708,000USD21,121,000USD2,852,000USD
    Unclassified Investing Cash Flow-6,183,000USD2,248,000USD-103,520,001USD2,702,000USD2,385,000USD———
    Unclassified Financing Cash Flow-21,665,000USD———-15,734,000USD—-21,121,000USD-2,928,000USD
    Change To Liabilities———-22,469,000USD40,695,000USD24,121,000USD14,797,000USD4,240,000USD
    Sale Purchase Of Stock————65,794,000USD110,542,000USD79,621,000USD56,252,000USD
    Exchange Rate Changes————71,000USD———
    Cash And Cash Equivalents Changes————233,386,000USD158,625,000USD87,448,000USD-25,293,000USD
    Unclassified Operating Cash Flow—————-14,794,000USD—1,166,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    PeriodDimensionBusiness / regionRevenueCurrencySource
    Q2 2026Quarterly · 2026-06-30ProductLicense And Other Revenues54,513,000USDDisclosure
    Q2 2026Quarterly · 2026-06-30ProductResearch And Development Services1,216,000USDDisclosure
    Q3 2024Quarterly · 2024-09-30ProductCollaborative And Other Research And Development1,019,000USD0001628280-25-048785
    Q3 2024Quarterly · 2024-09-30ProductORLADEYO116,319,000USD0001628280-25-048785
    Q3 2024Quarterly · 2024-09-30ProductOther Income From Contract With Customer766,000USD0001628280-25-048785
    Q1 2023Quarterly · 2023-03-31ProductCollaborative And Other Research And Development612,000USD0001628280-24-021069
    Q1 2023Quarterly · 2023-03-31ProductORLADEYO68,414,000USD0001628280-24-021069
    Q1 2023Quarterly · 2023-03-31ProductOther Income From Contract With Customer364,000USD0001628280-24-021069
    FY 2022Yearly · 2022-12-31ProductCollaborative And Other Research And Development214,000USD0001628280-23-005259
    FY 2022Yearly · 2022-12-31ProductMilestone0USD0001628280-23-005259
    FY 2022Yearly · 2022-12-31ProductProduct267,710,000USD0001628280-23-005259
    FY 2022Yearly · 2022-12-31ProductRoyalty2,903,000USD0001628280-23-005259
    Q3 2022Quarterly · 2022-09-30ProductCollaborative And Other Research And Development14,000USD0001628280-22-028463
    Q3 2022Quarterly · 2022-09-30ProductMilestone Revenue0USD0001628280-22-028463
    Q3 2022Quarterly · 2022-09-30ProductProduct75,213,000USD0001628280-22-028463
    Q3 2022Quarterly · 2022-09-30ProductRoyalty600,000USD0001628280-22-028463
    Q2 2022Quarterly · 2022-06-30ProductCollaborative And Other Research And Development104,000USD0001628280-22-021373
    Q2 2022Quarterly · 2022-06-30ProductMilestone Revenue0USD0001628280-22-021373
    Q2 2022Quarterly · 2022-06-30ProductProduct64,888,000USD0001628280-22-021373
    Q2 2022Quarterly · 2022-06-30ProductRoyalty540,000USD0001628280-22-021373
    Q1 2022Quarterly · 2022-03-31ProductCollaborative And Other Research And Development377,000USD0001628280-23-016458
    Q1 2022Quarterly · 2022-03-31ProductORLADEYO49,704,000USD0001628280-23-016458
    Q1 2022Quarterly · 2022-03-31ProductOther Income From Contract With Customer219,000USD0001628280-23-016458
    FY 2021Yearly · 2021-12-31ProductCollaborative And Other Research And Development5,920,000USD0001628280-23-005259
    FY 2021Yearly · 2021-12-31ProductMilestone15,000,000USD0001628280-23-005259
    FY 2021Yearly · 2021-12-31ProductProduct136,350,000USD0001628280-23-005259
    FY 2021Yearly · 2021-12-31ProductRoyalty-100,000USD0001628280-23-005259
    Q3 2021Quarterly · 2021-09-30ProductCollaborative And Other Research And Development1,531,000USD0001628280-22-028463
    Q3 2021Quarterly · 2021-09-30ProductMilestone Revenue0USD0001628280-22-028463
    Q3 2021Quarterly · 2021-09-30ProductProduct39,141,000USD0001628280-22-028463
    Q3 2021Quarterly · 2021-09-30ProductRoyalty322,000USD0001628280-22-028463
    Q2 2021Quarterly · 2021-06-30ProductCollaborative And Other Research And Development1,401,000USD0001628280-22-021373
    Q2 2021Quarterly · 2021-06-30ProductMilestone Revenue15,000,000USD0001628280-22-021373
    Q2 2021Quarterly · 2021-06-30ProductProduct33,430,000USD0001628280-22-021373
    Q2 2021Quarterly · 2021-06-30ProductRoyalty128,000USD0001628280-22-021373
    FY 2020Yearly · 2020-12-31ProductCollaborative And Other Research And Development11,130,000USD0001628280-23-005259
    FY 2020Yearly · 2020-12-31ProductMilestone0USD0001628280-23-005259
    FY 2020Yearly · 2020-12-31ProductProduct3,301,000USD0001628280-23-005259
    FY 2020Yearly · 2020-12-31ProductRoyalty3,381,000USD0001628280-23-005259
    FY 2019Yearly · 2019-12-31ProductCollaborative And Other Research And Development24,999,000USD0001171843-22-001460
    FY 2019Yearly · 2019-12-31ProductProduct17,533,000USD0001171843-22-001460
    FY 2019Yearly · 2019-12-31ProductRoyalty6,303,000USD0001171843-22-001460
    FY 2018Yearly · 2018-12-31ProductCollaborative And Other Research And Development14,552,000USD0001171843-21-001411
    FY 2018Yearly · 2018-12-31ProductRoyalty6,101,000USD0001171843-21-001411
    FY 2017Yearly · 2017-12-31ProductCollaborative And Other Research And Development13,142,000USD0001171843-20-001710
    FY 2017Yearly · 2017-12-31ProductProduct1,501,000USD0001171843-20-001710
    FY 2017Yearly · 2017-12-31ProductRoyalty10,543,000USD0001171843-20-001710
    FY 2016Yearly · 2016-12-31ProductCollaborative And Other Research And Development14,402,000USD0001171843-19-001727
    FY 2016Yearly · 2016-12-31ProductProduct2,269,000USD0001171843-19-001727
    FY 2016Yearly · 2016-12-31ProductRoyalty9,682,000USD0001171843-19-001727

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.