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    APRE

    Aprea Therapeutics, Inc.

    Company overview

    Market capitalization
    $9.47M
    Employees
    8
    Latest publication
    2026-09-29
    About Aprea Therapeutics, Inc.

    Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid tumor indications. The company is headquartered in Doylestown, Pennsylvania.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Revenue118,111USD0USD3,337USD1,848USD118,111USD162,463USD205,817USD354,621USD
    Research Development2,462,042USD1,611,167USD1,008,839USD1,638,917USD1,912,213USD2,483,066USD2,359,086USD2,846,399USD
    Total Operating Expenses4,032,180USD3,424,984USD2,643,093USD3,117,388USD1,593,671USD1,764,978USD1,072,776USD1,605,238USD
    Net Income-3,591,304USD-3,287,917USD-2,455,630USD-2,972,410USD-3,238,870USD-3,932,659USD-2,894,799USD-3,783,769USD
    Cost Of Revenue—5,428USD-4,378,993USD5,429USD1,912,213USD2,483,066USD2,359,086USD2,846,399USD
    Gross Profit—-5,428USD4,382,330USD-3,581USD-1,794,102USD-2,320,603USD-2,153,269USD-2,491,778USD
    Selling General Administrative—1,819,245USD1,637,591USD1,480,319USD1,593,671USD1,764,979USD1,072,776USD1,605,238USD
    Operating Income—-3,430,412USD-2,643,093USD-3,117,388USD-3,387,773USD-4,085,581USD-3,226,045USD-4,097,016USD
    Interest Income—134,784USD118,664USD150,669USD178,027USD204,726USD274,626USD348,741USD
    Net Interest Income—134,784USD118,664USD150,669USD178,027USD204,726USD274,626USD348,741USD
    Income Before Tax—-3,287,917USD-2,455,630USD-2,972,410USD-3,238,870USD-3,932,659USD-2,894,799USD-3,783,769USD
    Net Income From Continuing Ops—-3,287,917USD-2,455,630USD-2,972,410USD-3,238,870USD-3,932,659USD-2,894,799USD-3,783,769USD
    Ebit—-3,430,411USD-2,643,093USD-3,117,388USD-3,387,773USD-4,085,581USD-3,226,045USD-4,097,016USD
    Ebitda—-3,424,983USD-2,637,664USD-3,111,959USD-3,382,345USD-4,080,153USD-3,220,617USD-4,091,586USD
    Depreciation And Amortization—5,428USD5,429USD5,429USD5,428USD5,428USD5,428USD5,430USD
    Reconciled Depreciation—5,428USD5,429USD5,429USD5,428USD5,429USD5,428USD5,429USD
    Total Other Income Expense Net—142,495USD187,463USD144,978USD148,903USD152,922USD331,246USD313,247USD
    Unclassified Operating Expenses————-1,912,213USD-2,483,067USD-2,359,086USD-2,846,399USD
    Income Tax Expense——————3USD—
    SourceDisclosurePreliminaryLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Revenue285,759USD1,502,581USD583,231USD0USD0USD0USD0USD0USD
    Cost Of Revenue21,715USD9,363,537USD7,052USD16,402,273USD271,677USD229,610USD170,254USD8,316USD
    Gross Profit264,044USD-7,860,956USD576,179USD-16,402,273USD-271,677USD-229,610USD-170,254USD-8,316USD
    Research Development7,043,035USD9,363,537USD7,627,491USD92,422,457USD23,895,875USD37,879,325USD20,950,672USD14,194,732USD
    Selling General Administrative6,476,560USD6,458,699USD8,427,703USD20,969,771USD13,550,478USD14,931,887USD8,593,626USD2,294,671USD
    Total Operating Expenses13,233,836USD6,458,699USD16,048,142USD96,989,955USD37,174,676USD52,811,212USD29,374,044USD16,489,403USD
    Operating Income-13,233,836USD-14,319,655USD-15,471,963USD-113,392,228USD-37,446,353USD-52,811,212USD-29,544,298USD-16,489,403USD
    Interest Income652,086USD1,289,144USD1,224,133USD448,667USD1,648USD222,652USD1,484,490USD961,140USD
    Net Interest Income652,086USD1,289,144USD1,156,928USD448,667USD1,648USD222,652USD156,351USD-182USD
    Income Before Tax-12,599,569USD-12,958,711USD-14,286,756USD-112,662,027USD-37,127,303USD-53,478,812USD-28,059,807USD-15,528,269USD
    Net Income-12,599,569USD-12,958,711USD-14,286,756USD-112,662,027USD-36,536,576USD-53,916,802USD-28,059,807USD-15,528,269USD
    Net Income From Continuing Ops-12,599,569USD-12,958,711USD-13,285,644USD-112,662,027USD-37,127,303USD-53,478,812USD-28,059,807USD-15,528,269USD
    Ebit-13,233,836USD-14,319,655USD-14,286,760USD-37,372,044USD-37,127,305USD-53,478,810USD-28,059,808USD-15,528,273USD
    Ebitda-13,212,121USD-14,297,337USD-14,279,708USD-37,367,641USD-36,855,628USD-53,249,200USD-27,889,554USD-15,519,957USD
    Depreciation And Amortization21,715USD22,318USD7,052USD4,403USD271,677USD229,610USD170,254USD8,316USD
    Reconciled Depreciation21,715USD22,318USD-319USD186,445USD271,677USD229,610USD170,254USD8,316USD
    Total Other Income Expense Net634,267USD1,360,944USD1,185,207USD730,201USD319,050USD-667,600USD1,484,491USD961,134USD
    Unclassified Operating Expenses—-9,363,537USD—-16,402,273USD————
    Selling And Marketing Expenses——7,052USD—————
    Income Tax Expense——-2USD112,213,360USD-590,727USD437,990USD-1,654,745USD961,316USD
    Interest Expense———448,667USD1,648USD222,652USD156,351USD182USD
    Net Income Applicable To Common Shares———-112,662,027USD-37,127,303USD-53,478,812USD-28,059,807USD-15,528,269USD
    Non Operating Income Net Other—————-667,600USD—0USD
    Minority Interest———————0USD
    Discontinued Operations———————0USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets42,289,924USD48,112,386USD15,933,401USD14,321,316USD17,309,710USD20,222,083USD23,979,493USD26,893,969USD
    Cash And Equivalents41,233,428USD———————
    Total Current Assets41,913,114USD47,245,440USD15,561,246USD13,943,988USD16,927,210USD19,834,410USD23,576,139USD26,483,820USD
    Other Current Assets679,686USD779,238USD961,899USD225,936USD395,011USD558,689USD726,254USD234,195USD
    Other Non Current Assets271,162USD———————
    Total Liabilities3,819,663USD———————
    Total Current Liabilities3,092,302USD5,296,646USD2,764,358USD2,681,107USD3,167,668USD3,361,098USD3,360,975USD3,635,888USD
    Total Stockholder Equity38,470,261USD42,815,740USD12,441,682USD11,640,209USD13,414,681USD15,549,922USD19,307,455USD21,947,018USD
    Total Equity Including Noncontrolling Interest38,470,261USD———————
    Property Plant Equipment Net64,033USD54,379USD59,807USD65,236USD70,665USD76,093USD81,522USD86,950USD
    Accounts Payable935,139USD2,940,756USD713,668USD641,322USD1,195,838USD1,281,651USD1,352,240USD1,153,880USD
    Common Stock12,391USD11,983USD8,192USD5,979USD5,752USD5,513USD5,481USD5,435USD
    Retained Earnings-340,520,662USD-336,929,358USD-333,641,441USD-331,185,811USD-328,213,401USD-324,974,531USD-321,041,872USD-318,147,073USD
    Accumulated Other Comprehensive Income-10,617,617USD-10,625,700USD-10,634,714USD-10,629,534USD-10,628,417USD-10,626,736USD-10,627,379USD-10,604,747USD
    Total Liab—5,296,646USD3,491,719USD2,681,107USD3,895,029USD4,672,161USD4,672,038USD4,946,951USD
    Other Current Liab—2,355,890USD2,050,690USD2,039,785USD1,971,830USD2,079,447USD2,008,735USD2,482,008USD
    Capital Stock—11,983USD8,192USD5,979USD5,752USD5,513USD5,481USD5,435USD
    Other Assets—1USD——————
    Cash—46,466,202USD14,599,347USD13,718,052USD16,532,199USD19,275,721USD22,849,885USD26,249,625USD
    Cash And Short Term Investments—46,466,202USD14,599,347USD13,718,052USD16,532,199USD19,275,721USD22,849,885USD26,249,625USD
    Net Debt—-46,466,202USD-14,599,347USD-13,718,052USD-16,532,199USD-19,275,721USD-22,849,885USD-26,249,625USD
    Property Plant Equipment Gross—54,379USD153,962USD65,236USD70,665USD76,093USD153,962USD86,950USD
    Common Stock Shares Outstanding—7,687,961shares7,687,961shares6,372,938shares6,083,329shares5,993,866shares5,954,700shares5,939,755shares
    Non Current Assets Total—866,945USD372,155USD377,328USD382,500USD387,673USD403,354USD410,149USD
    Non Current Liabilities Total—727,361USD727,361USD727,361USD727,361USD1,311,063USD1,311,063USD1,311,063USD
    Non Currrent Assets Other—271,161USD312,348USD271,162USD311,835USD271,162USD281,662USD323,199USD
    Net Working Capital—41,948,794USD12,796,888USD11,262,881USD13,759,542USD16,473,312USD20,215,164USD22,847,932USD
    Unclassified Equity—390,346,832USD356,701,453USD353,443,596USD352,244,995USD351,140,163USD350,965,744USD350,687,968USD
    Unclassified Non Current Liabilities—————1,311,063USD1,311,063USD1,311,063USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Total Assets15,933,401USD23,979,493USD22,650,174USD30,155,827USD56,823,463USD92,805,219USD133,607,885USD66,022,638USD
    Other Current Assets961,899USD726,254USD914,275USD1,366,859USD3,508,358USD3,399,019USD2,955,878USD322,146USD
    Total Liab3,491,719USD4,672,038USD4,385,605USD4,512,149USD7,316,499USD15,410,012USD9,364,355USD117,458,740USD
    Total Stockholder Equity12,441,682USD19,307,455USD18,264,569USD25,643,678USD49,506,964USD77,395,207USD124,243,530USD-51,436,102USD
    Other Current Liab2,050,690USD2,008,735USD2,186,262USD2,358,332USD5,352,996USD10,571,237USD6,642,553USD3,128,772USD
    Common Stock8,192USD5,481USD3,736USD2,655USD1,092USD21,187USD21,023USD127,091USD
    Capital Stock8,192USD5,481USD3,736USD2,655USD21,859USD21,187USD21,023USD127,091USD
    Retained Earnings-333,641,441USD-321,041,872USD-308,083,161USD-293,796,405USD-181,134,378USD-144,007,075USD-90,528,263USD-62,468,456USD
    Cash14,599,347USD22,849,885USD21,606,820USD28,786,647USD53,076,052USD89,017,686USD130,088,869USD65,675,931USD
    Cash And Short Term Investments14,599,347USD22,849,885USD21,606,820USD28,786,647USD53,076,052USD89,017,686USD130,088,869USD65,675,931USD
    Total Current Assets15,561,246USD23,576,139USD22,521,095USD30,153,506USD56,584,410USD92,416,705USD133,044,747USD65,998,077USD
    Total Current Liabilities2,764,358USD3,360,975USD4,385,605USD3,201,086USD7,316,499USD15,331,165USD9,061,734USD4,868,109USD
    Net Debt-14,599,347USD-22,849,885USD-21,606,820USD-28,786,647USD-52,885,581USD-88,682,530USD-129,543,919USD-65,675,931USD
    Accounts Payable713,668USD1,352,240USD1,670,369USD842,754USD1,773,032USD4,503,619USD2,176,852USD1,739,337USD
    Property Plant Equipment Net59,807USD81,522USD88,362USD2,321USD209,681USD359,131USD563,031USD24,450USD
    Property Plant Equipment Gross153,962USD153,962USD138,484USD2,321USD239,053USD359,131USD563,031USD24,450USD
    Accumulated Other Comprehensive Income-10,634,714USD-10,627,379USD-10,611,273USD-10,623,408USD-10,358,956USD-10,037,261USD-11,533,778USD-8,761,325USD
    Common Stock Shares Outstanding6,538,722shares5,509,921shares3,617,607shares82,852shares1,064,327shares1,056,682shares1,004,864shares703,783shares
    Non Current Assets Total372,155USD403,354USD129,079USD2,321USD239,053USD388,514USD563,138USD24,561USD
    Non Current Liabilities Total727,361USD1,311,063USD1,311,063USD1,311,063USD1,963,503USD78,847USD302,621USD112,590,631USD
    Non Currrent Assets Other312,348USD281,662USD40,717USD—29,372USD29,383USD107USD111USD
    Net Working Capital12,796,888USD20,215,164USD18,135,490USD26,952,420USD49,267,911USD77,085,540USD123,983,013USD61,129,968USD
    Unclassified Equity356,701,453USD350,965,744USD336,951,531USD330,058,181USD240,977,347USD231,397,169USD226,263,525USD19,539,497USD
    Unclassified Non Current Liabilities—1,311,063USD1,311,063USD1,311,063USD1,963,503USD——112,590,631USD
    Current Deferred Revenue——528,974USD—————
    Net Tangible Assets———25,643,678USD49,506,964USD77,395,207USD124,243,530USD-51,436,102USD
    Other Assets————29,372USD349,999USD107USD111USD
    Short Term Debt————190,471USD256,309USD242,329USD0USD
    Short Long Term Debt Total————190,471USD335,156USD544,950USD—
    Intangible Assets———————0USD
    Deferred Long Term Liab———————0USD
    Other Liab———————0USD
    Good Will———————0USD
    Short Long Term Debt———————0USD
    Long Term Debt———————0USD
    Long Term Investments———————0USD
    Short Term Investments———————0USD
    Inventory———————0USD
    Accumulated Depreciation———————0USD
    Additional Paid In Capital———————0USD
    Treasury Stock———————0USD
    Non Current Liabilities Other———————0USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow YTD

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USD
    Depreciation11,174USD
    Change To Liabilities358,429USD
    Change In Working Capital502,857USD
    Operating Cash Flow-6,035,489USD
    Capital Expenditures-15,400USD
    Investing Cash Flow-15,400USD
    Financing Cash Flow32,686,442USD
    Effect Of Forex Changes On Cash-1,043USD
    Change In Cash26,634,510USD
    End Cash Flow41,275,043USD
    SourceDisclosureDeterministicFinal

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-3,287,917USD-2,455,630USD-2,972,410USD-3,238,870USD-3,932,659USD-2,894,799USD-3,783,769USD-3,470,052USD
    Depreciation5,428USD5,429USD5,429USD5,428USD5,429USD5,428USD5,429USD5,304USD
    Stock Based Compensation101,068USD109,024USD113,754USD136,729USD118,634USD126,028USD149,090USD128,488USD
    Other Non Cash Items-7,711USD79,072USD42,442USD29,124USD51,803USD-39,185USD35,494USD5,502USD
    Change In Working Capital432,406USD-695,774USD-338,610USD-63,165USD125,630USD-708,376USD1,125,454USD-310,863USD
    Total Cash From Operating Activities-2,756,726USD-3,066,902USD-3,263,148USD-3,130,754USD-3,631,163USD-3,510,904USD-2,468,302USD-3,641,621USD
    Capital Expenditures0USD0USD-1USD0USD0USD-380USD-209USD-7,500USD
    Free Cash Flow-2,756,726USD-3,066,900USD-3,263,150USD-3,130,754USD-3,631,163USD-3,510,904USD-2,468,302USD-3,649,121USD
    Total Cash From Financing Activities34,624,149USD4,003,556USD370,686USD384,879USD55,849USD134,405USD-1,155USD-21,060USD
    Issuance Of Capital Stock35,098,813USD4,213,209USD375,378USD399,785USD59,234USD140,758USD0USD0USD
    Change In Cash31,867,075USD881,295USD-2,814,146USD-2,743,267USD-3,573,916USD-3,401,107USD-2,444,792USD-3,675,005USD
    Begin Period Cash Flow14,640,533USD13,718,052USD16,532,198USD19,316,139USD22,890,055USD26,291,162USD28,735,954USD32,410,959USD
    End Period Cash Flow46,507,608USD14,599,347USD13,718,052USD16,572,872USD19,316,139USD22,890,055USD26,291,162USD28,735,954USD
    Other Cashflows From Financing Activities34,624,149USD—357,940USD-14,906USD-3,385USD-6,353USD-1,155USD-21,060USD
    Unclassified Financing Cash Flow-35,098,813USD———————
    Investments——0USD0USD0USD0USD0USD-7,500USD
    Total Cashflows From Investing Activities—————384USD-209USD-7,500USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USDFY 20182018-12-31 · USD
    Net Income-12,599,569USD-12,958,711USD-14,286,756USD-112,662,027USD-37,127,303USD-53,478,812USD-28,059,807USD-15,528,269USD
    Depreciation21,715USD22,318USD7,052USD186,445USD271,677USD229,610USD170,254USD8,316USD
    Stock Based Compensation478,141USD489,436USD444,459USD16,981,266USD7,813,743USD4,983,023USD1,345,722USD329,184USD
    Other Non Cash Items134,369USD-54,365USD38,926USD72,241,759USD-317,402USD890,252USD-1,328,140USD-961,316USD
    Change In Working Capital-929,095USD-1,055,396USD1,618,711USD-1,758,579USD-8,326,894USD5,573,255USD1,163,264USD901,851USD
    Total Cash From Operating Activities-12,894,439USD-13,556,718USD-12,177,608USD-25,011,136USD-37,686,179USD-41,802,672USD-26,708,707USD-15,250,234USD
    Capital Expenditures0USD-15,478USD-93,093USD0USD0USD-25,709USD-30,901USD-3,702USD
    Free Cash Flow-12,894,439USD-13,572,196USD-12,270,701USD-25,011,136USD-37,686,179USD-41,828,381USD-26,739,608USD-15,253,936USD
    Total Cash From Financing Activities4,640,238USD14,821,895USD5,139,990USD682,973USD1,747,012USD150,949USD92,575,538USD56,366,742USD
    Issuance Of Capital Stock5,047,606USD16,140,356USD5,887,444USD682,973USD1,538,645USD86,906,179USD92,504,541USD56,364,645USD
    Change In Cash-8,249,522USD1,242,518USD-7,139,110USD-24,289,405USD-35,941,634USD-41,071,183USD64,412,938USD41,274,443USD
    Begin Period Cash Flow22,890,055USD21,647,537USD28,786,647USD53,076,052USD89,017,686USD130,088,869USD65,675,931USD24,401,488USD
    End Period Cash Flow14,640,533USD22,890,055USD21,647,537USD28,786,647USD53,076,052USD89,017,686USD130,088,869USD65,675,931USD
    Other Cashflows From Financing Activities4,640,238USD-1,318,461USD-648,928USD-69,424,194USD208,367USD150,949USD5,669,359USD56,366,742USD
    Unclassified Financing Cash Flow-5,047,606USD——69,424,194USD—-86,906,179USD-5,669,361USD-56,366,740USD
    Investments—-15,478USD-85,943USD0USD-16,290USD-25,709USD-30,901USD-3,702USD
    Total Cashflows From Investing Activities—-15,478USD-93,093USD——-25,709USD-30,901USD-3,702USD
    Change To Liabilities———-858,513USD-2,730,587USD2,326,767USD437,515USD214,380USD
    Sale Purchase Of Stock——————92,575,540USD56,366,740USD
    Change To Account Receivables———————0USD
    Change To Inventory———————0USD
    Net Borrowings———————0USD
    Dividends Paid———————0USD
    Exchange Rate Changes———————0USD
    Cash And Cash Equivalents Changes———————0USD
    Other Cashflows From Investing Activities———————0USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    No revenue breakdown is currently published for this company.

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.