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    AMLX

    Amylyx Pharmaceuticals, Inc.

    Company overview

    Market capitalization
    $3.33B
    Employees
    136
    Latest publication
    2026-09-29
    About Amylyx Pharmaceuticals, Inc.

    Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ2 20242024-06-30 · USDQ4 20232023-12-31 · USD
    Total Revenue0USD0USD0USD0USD0USD-665,000USD-1,023,000USD108,449,000USD
    Cost Of Revenue98,000USD108,000USD19,855,000USD141,000USD22,119,000USD160,000USD7,626,000USD9,360,000USD
    Gross Profit-98,000USD-108,000USD-19,855,000USD-141,000USD-22,119,000USD-665,000USD-8,649,000USD99,089,000USD
    Research Development27,610,000USD21,105,000USD19,855,000USD27,076,000USD22,119,000USD22,892,000USD23,139,000USD44,914,000USD
    Selling General Administrative16,169,000USD15,392,000USD16,172,000USD15,640,000USD15,684,000USD14,397,000USD21,647,000USD42,741,000USD
    Total Operating Expenses43,779,000USD36,497,000USD16,172,000USD42,716,000USD15,684,000USD39,989,000USD44,786,000USD97,155,000USD
    Operating Income-43,779,000USD-36,605,000USD-36,027,000USD-42,857,000USD-37,803,000USD-40,654,000USD-53,435,000USD1,934,000USD
    Interest Income2,570,000USD3,290,000USD1,821,000USD1,960,000USD2,231,000USD2,316,000USD4,069,000USD4,371,000USD
    Net Interest Income2,570,000USD3,290,000USD1,821,000USD1,960,000USD2,231,000USD2,316,000USD4,069,000USD4,371,000USD
    Income Before Tax-41,284,000USD-32,953,000USD-34,386,000USD-41,443,000USD-35,907,000USD-38,181,000USD-72,700,000USD6,476,000USD
    Net Income-41,284,000USD-32,999,000USD-34,386,000USD-41,443,000USD-35,907,000USD-37,546,000USD-72,700,000USD4,731,000USD
    Net Income From Continuing Ops-41,284,000USD-32,999,000USD-34,386,000USD-41,443,000USD-35,907,000USD-37,546,000USD-72,700,000USD4,731,000USD
    Ebit-41,284,000USD-31,057,000USD-34,386,000USD-41,443,000USD-35,907,000USD-38,181,000USD-72,700,000USD6,476,000USD
    Ebitda-41,186,000USD-30,949,000USD-34,266,000USD-41,302,000USD-35,751,000USD-38,021,000USD-72,492,000USD6,777,000USD
    Depreciation And Amortization98,000USD108,000USD120,000USD141,000USD156,000USD160,000USD208,000USD301,000USD
    Reconciled Depreciation98,000USD108,000USD120,000USD141,000USD156,000USD160,000USD208,000USD301,000USD
    Total Other Income Expense Net2,495,000USD3,651,000USD1,641,000USD1,414,000USD1,896,000USD2,473,000USD-19,265,000USD4,542,000USD
    Income Tax Expense—46,000USD———-635,000USD—1,745,000USD
    Tax Provision—46,000USD0USD0USD0USD-635,000USD0USD1,745,000USD
    Unclassified Operating Expenses——-19,855,000USD—-22,119,000USD———
    Selling And Marketing Expenses—————2,700,000USD—9,500,000USD
    Interest Expense———————3,456,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20232023-12-31 · USDFY 20212021-12-31 · USDFY 20192019-12-31 · USD
    Total Revenue0USD380,786,000USD285,000USD1,426,000USD
    Cost Of Revenue525,000USD25,441,000USD52,000USD11,899,000USD
    Gross Profit-525,000USD355,345,000USD285,000USD-10,473,000USD
    Research Development90,404,000USD128,187,000USD44,040,000USD11,899,000USD
    Selling General Administrative62,887,000USD178,856,000USD38,933,000USD3,081,000USD
    Total Operating Expenses152,766,000USD316,543,000USD82,688,000USD13,554,000USD
    Operating Income-153,291,000USD38,802,000USD-82,688,000USD-13,554,000USD
    Interest Income9,302,000USD16,155,000USD36,000USD176,000USD
    Net Interest Income9,302,000USD16,155,000USD36,000USD-1,100,000USD
    Income Before Tax-144,689,000USD54,297,000USD-87,931,000USD-13,716,000USD
    Income Tax Expense46,000USD5,026,000USD-52,000USD1,100,000USD
    Tax Provision46,000USD5,026,000USD0USD—
    Net Income-144,735,000USD49,271,000USD-87,879,000USD-14,816,000USD
    Net Income From Continuing Ops-144,735,000USD49,271,000USD-87,931,000USD-13,716,000USD
    Ebit-144,689,000USD54,297,000USD-82,688,000USD-12,440,000USD
    Ebitda-144,164,000USD55,385,000USD-82,636,000USD1,114,000USD
    Depreciation And Amortization525,000USD1,088,000USD52,000USD13,554,000USD
    Reconciled Depreciation525,000USD1,088,000USD52,000USD0USD
    Total Other Income Expense Net8,602,000USD15,495,000USD-5,243,000USD-162,000USD
    Selling And Marketing Expenses—9,500,000USD——
    Interest Expense——36,000USD1,276,000USD
    Net Income Applicable To Common Shares——-87,931,000USD-13,716,000USD
    Unclassified Operating Expenses———-1,426,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets264,564,000USD293,603,000USD332,645,000USD362,741,000USD194,598,000USD219,676,000USD193,634,000USD250,713,000USD
    Cash And Equivalents49,326,000USD———————
    Cash And Short Term Investments250,760,000USD279,768,000USD316,979,000USD343,990,000USD180,826,000USD204,068,000USD176,501,000USD234,395,000USD
    Short Term Investments201,434,000USD50,632,000USD90,328,000USD118,812,000USD122,741,000USD144,304,000USD99,110,000USD162,556,000USD
    Total Current Assets256,338,000USD285,024,000USD323,671,000USD353,383,000USD186,890,000USD216,144,000USD189,432,000USD245,263,000USD
    Other Current Assets5,578,000USD5,156,000USD6,604,000USD9,161,000USD5,861,000USD11,776,000USD12,484,000USD9,137,000USD
    Total Liabilities25,397,000USD———————
    Total Current Liabilities21,150,000USD15,966,000USD22,688,000USD25,791,000USD21,424,000USD17,932,000USD28,406,000USD53,915,000USD
    Other Current Liabilities14,609,000USD———————
    Total Stockholder Equity239,167,000USD273,161,000USD305,259,000USD331,996,000USD167,877,000USD201,417,000USD164,765,000USD196,203,000USD
    Total Equity Including Noncontrolling Interest239,167,000USD———————
    Property Plant Equipment Net4,740,000USD5,093,000USD5,491,000USD5,875,000USD6,257,000USD2,072,000USD2,732,000USD3,527,000USD
    Accounts Payable5,533,000USD3,529,000USD3,519,000USD5,339,000USD3,294,000USD4,810,000USD2,939,000USD1,487,000USD
    Short Term Debt1,008,000USD1,155,000USD1,259,000USD981,000USD665,000USD1,055,000USD1,518,000USD1,972,000USD
    Common Stock11,000USD11,000USD11,000USD11,000USD9,000USD9,000USD7,000USD7,000USD
    Retained Earnings-836,134,000USD-792,711,000USD-751,427,000USD-718,428,000USD-684,042,000USD-642,599,000USD-606,692,000USD-569,146,000USD
    Accumulated Other Comprehensive Income19,000USD240,000USD404,000USD815,000USD551,000USD0USD-92,000USD641,000USD
    Total Liab—20,442,000USD27,386,000USD30,745,000USD26,721,000USD18,259,000USD28,869,000USD54,510,000USD
    Other Current Liab—11,282,000USD17,910,000USD19,471,000USD17,465,000USD12,067,000USD23,949,000USD50,456,000USD
    Capital Stock—11,000USD11,000USD11,000USD9,000USD9,000USD7,000USD7,000USD
    Cash—229,136,000USD226,651,000USD225,178,000USD58,085,000USD59,764,000USD77,391,000USD71,839,000USD
    Net Debt—-223,505,000USD-220,694,000USD-219,243,000USD-52,123,000USD-58,382,000USD-75,410,000USD-69,272,000USD
    Short Long Term Debt Total—5,631,000USD5,957,000USD5,935,000USD5,962,000USD1,382,000USD1,981,000USD2,567,000USD
    Net Receivables—100,000USD88,000USD232,000USD203,000USD300,000USD447,000USD1,731,000USD
    Property Plant Equipment Gross—5,093,000USD7,045,000USD5,875,000USD6,257,000USD2,072,000USD4,091,000USD3,527,000USD
    Common Stock Shares Outstanding—110,563,360shares94,565,567shares93,332,930shares89,138,568shares85,697,000shares68,593,499shares68,091,446shares
    Non Current Assets Total—8,579,000USD8,974,000USD9,358,000USD7,708,000USD3,532,000USD4,202,000USD5,450,000USD
    Non Current Liabilities Total—4,476,000USD4,698,000USD4,954,000USD5,297,000USD327,000USD463,000USD595,000USD
    Non Currrent Assets Other—3,486,000USD3,483,000USD2,500,000USD1,451,000USD1,460,000USD1,470,000USD1,923,000USD
    Net Working Capital—269,058,000USD300,983,000USD327,592,000USD165,466,000USD198,212,000USD161,026,000USD191,348,000USD
    Unclassified Non Current Liabilities—4,476,000USD4,698,000USD4,954,000USD5,297,000USD———
    Unclassified Equity—1,065,610,000USD1,056,260,000USD1,049,587,000USD851,350,000USD843,998,000USD771,535,000USD764,694,000USD
    Inventory——————0USD0USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USDFY 20192019-12-31 · USD
    Total Assets332,645,000USD193,634,000USD517,454,000USD391,453,000USD105,614,000USD14,104,000USD3,220,000USD
    Other Current Assets6,604,000USD12,484,000USD14,931,000USD10,113,000USD8,833,000USD762,000USD137,000USD
    Total Liab27,386,000USD28,869,000USD84,022,000USD50,846,000USD256,782,000USD80,829,000USD28,577,000USD
    Total Stockholder Equity305,259,000USD164,765,000USD433,432,000USD340,607,000USD-151,168,000USD-66,725,000USD-25,357,000USD
    Other Current Liab17,910,000USD23,949,000USD57,724,000USD38,312,000USD13,024,000USD3,713,000USD2,334,000USD
    Common Stock11,000USD7,000USD7,000USD7,000USD1,000USD1,000USD1,000USD
    Capital Stock11,000USD7,000USD7,000USD7,000USD1,000USD1,000USD1,000USD
    Retained Earnings-751,427,000USD-606,692,000USD-304,949,000USD-354,220,000USD-155,845,000USD-67,914,000USD-25,634,000USD
    Cash226,651,000USD77,391,000USD170,201,000USD62,526,000USD50,191,000USD12,877,000USD3,065,000USD
    Cash And Short Term Investments316,979,000USD176,501,000USD371,362,000USD346,945,000USD96,118,000USD12,877,000USD3,065,000USD
    Total Current Assets323,671,000USD189,432,000USD464,666,000USD382,133,000USD104,951,000USD13,639,000USD3,202,000USD
    Total Current Liabilities22,688,000USD28,406,000USD82,042,000USD46,609,000USD17,396,000USD7,326,000USD4,529,000USD
    Net Debt-220,694,000USD-75,410,000USD-165,964,000USD-56,249,000USD-50,191,000USD-11,452,000USD11,866,000USD
    Short Term Debt1,259,000USD1,518,000USD2,257,000USD2,040,000USD———
    Short Long Term Debt Total5,957,000USD1,981,000USD4,237,000USD6,277,000USD—1,425,000USD14,931,000USD
    Short Term Investments90,328,000USD99,110,000USD201,161,000USD284,419,000USD45,927,000USD0USD—
    Net Receivables88,000USD447,000USD40,050,000USD15,306,000USD0USD——
    Accounts Payable3,519,000USD2,939,000USD22,061,000USD6,257,000USD4,372,000USD3,613,000USD2,195,000USD
    Property Plant Equipment Net5,491,000USD2,732,000USD6,411,000USD8,135,000USD474,000USD151,000USD0USD
    Property Plant Equipment Gross7,045,000USD4,091,000USD8,039,000USD8,675,000USD527,000USD152,000USD—
    Accumulated Other Comprehensive Income404,000USD-92,000USD197,000USD-86,000USD9,000USD-72,062,000USD-7,675,000USD
    Common Stock Shares Outstanding94,565,567shares68,142,000shares69,991,340shares66,512,011shares57,864,186shares56,466,013shares56,466,013shares
    Non Current Assets Total8,974,000USD4,202,000USD52,788,000USD9,320,000USD663,000USD465,000USD18,000USD
    Non Current Liabilities Total4,698,000USD463,000USD1,980,000USD4,237,000USD239,386,000USD73,503,000USD24,048,000USD
    Non Currrent Assets Other3,483,000USD1,470,000USD46,377,000USD1,185,000USD189,000USD125,000USD18,000USD
    Net Working Capital300,983,000USD161,026,000USD382,624,000USD335,524,000USD87,555,000USD6,313,000USD-1,327,000USD
    Unclassified Non Current Liabilities4,698,000USD—1,980,000USD—239,316,000USD72,062,000USD7,675,000USD
    Unclassified Equity1,056,260,000USD771,535,000USD738,170,000USD694,899,000USD4,666,000USD73,249,000USD7,950,000USD
    Inventory—0USD38,323,000USD9,769,000USD0USD——
    Current Deferred Revenue——21,887,000USD————
    Unclassified Current Liabilities——-21,887,000USD————
    Other Assets———1USD1USD1USD18,000USD
    Non Current Liabilities Other———4,237,000USD35,000USD——
    Net Tangible Assets———340,607,000USD-151,168,000USD-66,725,000USD-25,357,000USD
    Other Liab————35,000USD16,000USD1,442,000USD
    Long Term Debt—————1,425,000USD14,931,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-41,284,000USD-32,999,000USD-34,386,000USD-41,443,000USD-35,907,000USD-37,546,000USD-72,704,000USD-72,700,000USD
    Depreciation98,000USD108,000USD120,000USD141,000USD156,000USD160,000USD221,000USD208,000USD
    Stock Based Compensation6,120,000USD6,386,000USD7,076,000USD7,350,000USD6,833,000USD6,741,000USD6,803,000USD9,570,000USD
    Other Non Cash Items3,444,000USD-1,490,000USD-1,243,000USD-1,259,000USD-1,703,000USD-1,660,000USD34,707,000USD5,037,000USD
    Change In Working Capital-5,260,000USD92,000USD-1,935,000USD9,963,000USD-9,203,000USD-26,703,000USD-10,597,000USD-8,695,000USD
    Total Cash From Operating Activities-36,882,000USD-27,903,000USD-30,368,000USD-25,248,000USD-39,824,000USD-59,008,000USD-41,570,000USD-66,580,000USD
    Capital Expenditures0USD-86,000USD-24,000USD-17,000USD-11,000USD-20,000USD-19,000USD-89,000USD
    Free Cash Flow-36,882,000USD-27,989,000USD-30,392,000USD-25,265,000USD-39,835,000USD-59,028,000USD-41,551,000USD-66,669,000USD
    Investments40,262,000USD29,554,000USD5,236,000USD22,994,000USD-43,659,000USD64,980,000USD38,816,000USD-28,961,000USD
    Total Cashflows From Investing Activities36,262,000USD29,468,000USD5,236,000USD22,994,000USD-43,659,000USD64,980,000USD38,816,000USD-28,961,000USD
    Total Cash From Financing Activities3,217,000USD-208,000USD191,606,000USD-31,000USD65,662,000USD110,000USD80,000USD27,000USD
    Change In Cash2,485,000USD1,475,000USD167,093,000USD-1,679,000USD-17,624,000USD5,557,000USD-2,438,000USD-95,553,000USD
    Begin Period Cash Flow226,651,000USD226,161,000USD58,085,000USD59,764,000USD78,837,000USD73,280,000USD75,718,000USD171,271,000USD
    End Period Cash Flow229,136,000USD227,636,000USD225,178,000USD58,085,000USD61,213,000USD78,837,000USD73,280,000USD75,718,000USD
    Other Cashflows From Financing Activities-3,942,000USD-256,897,000USD-2,164,000USD-103,000USD64,692,000USD110,000USD80,000USD27,000USD
    Unclassified Investing Cash Flow-4,000,000USD———43,659,000USD—36,222,000USD28,961,000USD
    Unclassified Financing Cash Flow7,159,000USD256,689,000USD193,770,000USD—1,855,000USD—-1,335,000USD—
    Change To Account Receivables—50,000USD-85,000USD205,000USD213,000USD980,000USD2,243,000USD16,564,000USD
    Change To Inventory—0USD0USD0USD0USD0USD0USD0USD
    Sale Purchase Of Stock————-885,000USD—1,335,000USD-20,000USD
    Other Cashflows From Investing Activities————-43,648,000USD—-36,203,000USD-28,872,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USD
    Net Income-144,735,000USD-301,743,000USD49,271,000USD-198,375,000USD-87,931,000USD-42,280,000USD
    Depreciation525,000USD904,000USD1,088,000USD487,000USD52,000USD1,000USD
    Stock Based Compensation27,645,000USD33,038,000USD37,161,000USD21,714,000USD3,136,000USD243,000USD
    Other Non Cash Items-5,695,000USD145,985,000USD-9,940,000USD-2,056,000USD5,349,000USD2,740,000USD
    Change To Account Receivables383,000USD39,602,000USD-24,744,000USD-15,306,000USD-144,000USD-15,306,000USD
    Change To Inventory0USD-9,253,000USD-73,129,000USD-9,769,000USD-9,769,000USD-9,769,000USD
    Change In Working Capital-1,083,000USD-45,831,000USD-65,661,000USD-1,641,000USD4,595,000USD2,599,000USD
    Total Cash From Operating Activities-123,343,000USD-167,647,000USD11,919,000USD-179,871,000USD-74,799,000USD-36,697,000USD
    Capital Expenditures-138,000USD-157,000USD-1,241,000USD-2,526,000USD-353,000USD-151,000USD
    Free Cash Flow-123,481,000USD-167,804,000USD10,678,000USD-182,397,000USD-75,152,000USD-36,848,000USD
    Investments14,177,000USD75,654,000USD-157,052,000USD-236,462,000USD-46,406,000USD-46,053,000USD
    Total Cashflows From Investing Activities14,039,000USD75,654,000USD92,053,000USD-238,988,000USD-46,406,000USD-151,000USD
    Total Cash From Financing Activities257,029,000USD348,000USD3,543,000USD431,789,000USD158,506,000USD46,823,000USD
    Change In Cash148,799,000USD-92,083,000USD107,675,000USD12,865,000USD37,314,000USD9,975,000USD
    Begin Period Cash Flow78,837,000USD170,920,000USD62,526,000USD50,380,000USD13,066,000USD3,091,000USD
    End Period Cash Flow227,636,000USD78,837,000USD170,201,000USD63,245,000USD50,380,000USD13,066,000USD
    Other Cashflows From Financing Activities-3,361,000USD-1,784,000USD-3,315,000USD-658,000USD132,610,000USD30,006,000USD
    Unclassified Financing Cash Flow260,390,000USD2,132,000USD10,173,000USD—-135,000,000USD-29,958,000USD
    Other Cashflows From Investing Activities—-36,203,000USD—-236,462,000USD3,000,000USD—
    Unclassified Investing Cash Flow—36,360,000USD250,346,000USD236,462,000USD-2,647,000USD46,053,000USD
    Net Borrowings——0USD0USD25,896,000USD16,817,000USD
    Sale Purchase Of Stock——-3,315,000USD434,636,000USD——
    Issuance Of Capital Stock——231,550,000USD432,447,000USD135,000,000USD29,958,000USD
    Change To Liabilities———1,854,000USD670,000USD1,418,000USD
    Cash And Cash Equivalents Changes———12,930,000USD——
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    No revenue breakdown is currently published for this company.

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.