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    ACRV

    Acrivon Therapeutics, Inc.

    Company overview

    Market capitalization
    $88.28M
    Employees
    74
    Latest publication
    2026-09-29
    About Acrivon Therapeutics, Inc.

    Acrivon Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops oncology medicines for patients whose tumors are predicted to be sensitive to each specific medicine by utilizing its generative phosphoproteomics platform. The company operates Acrivon Predictive Precision Proteomics (AP3), a precision medicine platform that enables the creation of drug specific proprietary OncoSignature companion diagnostics that are used to identify the patients to benefit from its drug candidates. Its lead clinical candidate is ACR-368, a selective small molecule inhibitor targeting CHK1 and CHK2 for the treatment of patients with endometrial and platinum-resistant ovarian cancer, and SCCs, such as SCCHN and anal cancer. The company is also developing ACR-2316, a dual WEE1 and PKMYT1 inhibitor small molecule candidate; and a preclinical stage AP3-and co-crystallography-based preclinical cell cycle program. The company was incorporated in 2018 and is based in Watertown, Massachusetts.

    Company website

    Financial statements

    Income Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Total Revenue0USD0USD0USD0USD0USD848,000USD0USD0USD
    Cost Of Revenue383,000USD-911,000USD300,000USD300,000USD311,000USD303,000USD300,000USD200,000USD
    Gross Profit-383,000USD911,000USD-300,000USD-300,000USD-311,000USD-303,000USD-300,000USD-200,000USD
    Research Development14,783,000USD15,046,000USD13,648,000USD16,182,000USD15,414,000USD18,327,000USD18,864,000USD15,025,000USD
    Selling General Administrative4,736,000USD5,370,000USD6,039,000USD6,467,000USD6,248,000USD6,324,000USD6,276,000USD6,412,000USD
    Total Operating Expenses19,519,000USD21,027,000USD19,687,000USD22,349,000USD21,351,000USD24,651,000USD25,140,000USD21,437,000USD
    Operating Income-19,902,000USD-20,116,000USD-19,687,000USD-22,649,000USD-21,662,000USD-24,954,000USD-25,140,000USD-21,437,000USD
    Interest Income989,000USD1,247,000USD1,506,000USD1,730,000USD1,996,000USD2,363,000USD2,698,000USD2,694,000USD
    Net Interest Income989,000USD1,247,000USD1,506,000USD1,730,000USD1,996,000USD2,363,000USD2,698,000USD2,694,000USD
    Income Before Tax-19,042,000USD-18,985,000USD-18,234,000USD-21,006,000USD-19,680,000USD-22,831,000USD-22,441,000USD-18,798,000USD
    Net Income-19,042,000USD-18,985,000USD-18,234,000USD-21,006,000USD-19,680,000USD-22,831,000USD-22,441,000USD-18,798,000USD
    Net Income From Continuing Ops-19,042,000USD-18,985,000USD-18,234,000USD-21,006,000USD-19,680,000USD-22,831,000USD-22,441,000USD-18,798,000USD
    Ebit-19,902,000USD-25,194,000USD-19,687,000USD-21,006,000USD-19,680,000USD-22,831,000USD-25,140,000USD-21,437,000USD
    Ebitda-19,519,000USD-26,105,000USD-19,338,000USD-20,706,000USD-19,369,000USD-22,528,000USD-24,889,000USD-21,209,000USD
    Depreciation And Amortization383,000USD-911,000USD349,000USD300,000USD311,000USD303,000USD251,000USD228,000USD
    Reconciled Depreciation383,000USD361,000USD349,000USD335,000USD311,000USD303,000USD251,000USD228,000USD
    Total Other Income Expense Net860,000USD1,131,000USD1,453,000USD1,643,000USD1,982,000USD2,123,000USD2,699,000USD2,639,000USD
    Income Tax Expense—————-180,724USD——
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Income Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USD
    Total Revenue0USD0USD0USD0USD0USD0USD
    Cost Of Revenue1,356,000USD1,006,000USD536,000USD1,095,000USD832,000USD13,000USD
    Gross Profit-1,356,000USD-1,006,000USD-536,000USD-1,095,000USD-832,000USD-13,000USD
    Research Development59,990,000USD63,992,000USD45,488,000USD23,949,000USD13,718,000USD1,870,000USD
    Selling General Administrative24,124,000USD25,207,000USD21,079,000USD8,708,000USD2,466,000USD1,298,000USD
    Unclassified Operating Expenses-1,356,000USD-1,006,000USD————
    Total Operating Expenses82,758,000USD88,193,000USD66,701,000USD32,657,000USD16,184,000USD3,168,000USD
    Operating Income-84,114,000USD-89,199,000USD-67,237,000USD-32,657,000USD-16,184,000USD-3,168,000USD
    Interest Income6,479,000USD9,201,000USD7,037,000USD———
    Net Interest Income6,479,000USD9,201,000USD7,037,000USD———
    Income Before Tax-77,905,000USD-80,556,000USD-60,388,000USD-31,167,000USD-16,243,000USD-5,306,000USD
    Net Income-77,905,000USD-80,556,000USD-60,388,000USD-29,677,000USD-16,243,000USD-5,306,000USD
    Net Income From Continuing Ops-77,905,000USD-80,556,000USD-50,065,000USD-31,167,000USD-16,243,000USD-5,306,000USD
    Ebit-84,114,000USD-80,556,000USD-60,388,000USD-32,657,000USD-16,184,000USD-5,306,000USD
    Ebitda-82,758,000USD-79,550,000USD-59,852,000USD-32,293,000USD-16,147,000USD-5,293,000USD
    Depreciation And Amortization1,356,000USD1,006,000USD536,000USD364,000USD37,000USD13,000USD
    Reconciled Depreciation1,356,000USD1,006,000USD512,000USD364,000USD37,000USD13,000USD
    Total Other Income Expense Net6,209,000USD8,643,000USD6,849,000USD1,490,000USD-59,000USD-2,138,000USD
    Selling And Marketing Expenses——134,000USD———
    Income Tax Expense——1USD-1,490,000USD-199,558USD-193,297USD
    Interest Expense———1,490,000USD59,000USD—
    Non Operating Income Net Other———1,490,000USD——
    Net Income Applicable To Common Shares———-31,167,000USD-16,243,000USD-5,306,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ2 20262026-06-30 · USDQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USD
    Total Assets99,092,000USD107,832,000USD129,717,000USD145,299,000USD158,583,000USD176,349,000USD196,588,000USD214,684,000USD
    Cash And Equivalents41,417,000USD———————
    Cash And Short Term Investments89,959,000USD97,737,000USD118,582,000USD129,254,000USD137,423,000USD149,635,000USD179,480,000USD187,453,000USD
    Short Term Investments48,542,000USD63,673,000USD77,083,000USD93,849,000USD95,528,000USD110,481,000USD139,662,000USD144,038,000USD
    Total Current Assets91,493,000USD99,220,000USD120,445,000USD130,361,000USD138,412,000USD151,327,000USD181,629,000USD188,984,000USD
    Other Current Assets1,534,000USD1,483,000USD1,863,000USD1,107,000USD989,000USD1,692,000USD2,149,000USD1,531,000USD
    Other Non Current Assets1,179,000USD———————
    Total Liabilities12,427,000USD———————
    Total Current Liabilities11,447,000USD11,054,000USD15,664,000USD14,891,000USD13,431,000USD13,550,000USD17,214,000USD14,819,000USD
    Total Stockholder Equity86,665,000USD95,515,000USD112,516,000USD128,603,000USD143,037,000USD160,390,000USD176,786,000USD196,892,000USD
    Total Equity Including Noncontrolling Interest86,665,000USD———————
    Property Plant Equipment Net6,225,000USD6,908,000USD7,416,000USD7,981,000USD8,124,000USD7,982,000USD8,025,000USD8,467,000USD
    Accounts Payable861,000USD1,162,000USD2,277,000USD996,000USD1,163,000USD3,691,000USD758,000USD1,506,000USD
    Short Term Debt1,135,000USD1,152,000USD1,172,000USD1,184,000USD1,148,000USD1,105,000USD1,057,000USD1,040,000USD
    Common Stock42,000USD38,000USD31,000USD31,000USD31,000USD31,000USD31,000USD31,000USD
    Retained Earnings-311,887,000USD-293,923,000USD-274,881,000USD-255,896,000USD-237,662,000USD-216,656,000USD-196,976,000USD-174,145,000USD
    Accumulated Other Comprehensive Income-33,000USD4,000USD111,000USD112,000USD106,000USD283,000USD447,000USD782,000USD
    Total Liab—12,317,000USD17,201,000USD16,696,000USD15,546,000USD15,959,000USD19,802,000USD17,792,000USD
    Other Current Liab—8,740,000USD12,215,000USD12,711,000USD11,120,000USD8,754,000USD15,399,000USD12,273,000USD
    Capital Stock—38,000USD31,000USD31,000USD31,000USD31,000USD31,000USD31,000USD
    Cash—34,064,000USD41,499,000USD35,405,000USD41,895,000USD39,154,000USD39,818,000USD43,415,000USD
    Net Debt—-31,649,000USD-38,790,000USD-32,416,000USD-38,632,000USD-35,640,000USD-36,173,000USD-39,402,000USD
    Short Long Term Debt Total—2,415,000USD2,709,000USD2,989,000USD3,263,000USD3,514,000USD3,645,000USD4,013,000USD
    Property Plant Equipment Gross—10,609,000USD10,734,000USD10,938,000USD10,732,000USD10,255,000USD9,987,000USD10,126,000USD
    Common Stock Shares Outstanding—38,724,803shares38,509,281shares38,560,464shares38,461,619shares38,350,444shares38,242,412shares38,105,131shares
    Non Current Assets Total—8,612,000USD9,272,000USD14,938,000USD20,171,000USD25,022,000USD14,959,000USD25,700,000USD
    Non Current Liabilities Total—1,263,000USD1,537,000USD1,805,000USD2,115,000USD2,409,000USD2,588,000USD2,973,000USD
    Non Currrent Assets Other—1,704,000USD1,856,000USD1,849,000USD1,848,000USD1,845,000USD1,845,000USD1,843,000USD
    Net Working Capital—88,166,000USD104,781,000USD115,470,000USD124,981,000USD137,777,000USD164,415,000USD174,165,000USD
    Unclassified Non Current Liabilities—1,263,000USD1,537,000USD1,805,000USD2,115,000USD2,409,000USD2,588,000USD2,973,000USD
    Unclassified Equity—389,358,000USD387,224,000USD384,325,000USD380,531,000USD376,701,000USD373,253,000USD370,193,000USD
    Long Term Investments——0USD5,108,000USD10,199,000USD15,195,000USD5,089,000USD15,390,000USD
    SourceDisclosureDeterministicFinalLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Balance sheet Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USD
    Total Assets129,717,000USD196,588,000USD138,265,000USD181,226,000USD106,587,000USD2,185,000USD
    Other Current Assets1,863,000USD2,149,000USD2,234,000USD4,344,000USD805,000USD136,000USD
    Total Liab17,201,000USD19,802,000USD17,070,000USD10,751,000USD130,396,000USD10,598,000USD
    Total Stockholder Equity112,516,000USD176,786,000USD121,195,000USD170,475,000USD-23,809,000USD-8,413,000USD
    Other Current Liab12,215,000USD15,399,000USD7,378,000USD4,817,000USD1,220,000USD419,000USD
    Common Stock31,000USD31,000USD23,000USD22,000USD2,000USD1,000USD
    Capital Stock31,000USD31,000USD23,000USD22,000USD2,000USD1,000USD
    Retained Earnings-274,881,000USD-196,976,000USD-116,420,000USD-56,032,000USD-24,865,000USD-8,622,000USD
    Cash41,499,000USD39,818,000USD36,015,000USD29,519,000USD99,603,000USD1,583,000USD
    Cash And Short Term Investments118,582,000USD179,480,000USD127,458,000USD127,751,000USD99,603,000USD1,583,000USD
    Total Current Assets120,445,000USD181,629,000USD129,692,000USD132,095,000USD100,408,000USD1,719,000USD
    Total Current Liabilities15,664,000USD17,214,000USD13,303,000USD6,516,000USD2,914,000USD613,000USD
    Net Debt-38,790,000USD-36,173,000USD-31,371,000USD-24,558,000USD-93,975,000USD-1,525,000USD
    Short Term Debt1,172,000USD1,057,000USD877,000USD726,000USD664,000USD58,000USD
    Short Long Term Debt Total2,709,000USD3,645,000USD4,644,000USD4,961,000USD5,628,000USD58,000USD
    Long Term Investments0USD5,089,000USD0USD41,881,000USD0USD—
    Short Term Investments77,083,000USD139,662,000USD91,443,000USD98,232,000USD0USD—
    Accounts Payable2,277,000USD758,000USD5,048,000USD904,000USD964,000USD136,000USD
    Property Plant Equipment Net7,416,000USD8,025,000USD7,908,000USD6,862,000USD5,791,000USD59,000USD
    Property Plant Equipment Gross10,734,000USD9,987,000USD8,864,000USD7,282,000USD5,847,000USD78,000USD
    Accumulated Other Comprehensive Income111,000USD447,000USD-83,000USD-95,000USD——
    Common Stock Shares Outstanding38,509,281shares38,296,428shares22,078,190shares21,920,634shares12,909,823shares12,909,823shares
    Non Current Assets Total9,272,000USD14,959,000USD8,573,000USD49,131,000USD6,179,000USD466,000USD
    Non Current Liabilities Total1,537,000USD2,588,000USD3,767,000USD4,235,000USD127,482,000USD9,985,000USD
    Non Currrent Assets Other1,856,000USD1,845,000USD665,000USD388,000USD388,000USD407,000USD
    Net Working Capital104,781,000USD164,415,000USD116,389,000USD125,579,000USD97,494,000USD1,106,000USD
    Unclassified Non Current Liabilities1,537,000USD2,588,000USD3,767,000USD—127,482,000USD9,985,000USD
    Unclassified Equity387,224,000USD373,253,000USD237,652,000USD226,558,000USD1,052,000USD—
    Other Assets——1USD388,000USD388,000USD407,000USD
    Current Deferred Revenue———69,000USD66,000USD—
    Non Current Liabilities Other———4,235,000USD——
    Net Tangible Assets———170,475,000USD-23,809,000USD-8,413,000USD
    Short Long Term Debt—————58,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Quarterly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricQ1 20262026-03-31 · USDQ4 20252025-12-31 · USDQ3 20252025-09-30 · USDQ2 20252025-06-30 · USDQ1 20252025-03-31 · USDQ4 20242024-12-31 · USDQ3 20242024-09-30 · USDQ2 20242024-06-30 · USD
    Net Income-19,042,000USD-18,985,000USD-18,234,000USD-21,006,000USD-19,680,000USD-22,831,000USD-22,441,000USD-18,798,000USD
    Depreciation383,000USD361,000USD300,000USD162,000USD311,000USD303,000USD300,000USD200,000USD
    Stock Based Compensation2,181,000USD3,091,000USD3,911,000USD3,927,000USD3,791,000USD3,707,000USD3,671,000USD3,566,000USD
    Other Non Cash Items2,615,000USD395,000USD4,185,000USD255,000USD-112,000USD-654,000USD2,654,000USD2,724,000USD
    Change In Working Capital-4,494,000USD-99,000USD1,466,000USD52,000USD-3,845,000USD2,115,000USD2,164,000USD1,971,000USD
    Total Cash From Operating Activities-20,538,000USD-15,237,000USD-12,283,000USD-16,610,000USD-19,535,000USD-17,360,000USD-17,323,000USD-13,903,000USD
    Capital Expenditures-14,000USD-219,000USD-899,000USD-493,000USD-58,000USD-827,000USD-989,000USD-137,000USD
    Free Cash Flow-20,552,000USD-15,456,000USD-13,182,000USD-17,103,000USD-19,593,000USD-18,187,000USD-18,312,000USD-14,040,000USD
    Investments13,141,000USD21,743,000USD5,911,000USD19,451,000USD19,214,000USD14,412,000USD16,011,000USD-88,044,000USD
    Total Cashflows From Investing Activities13,127,000USD21,524,000USD5,911,000USD19,451,000USD19,214,000USD14,412,000USD16,011,000USD-88,044,000USD
    Total Cash From Financing Activities-33,000USD-192,000USD-117,000USD-97,000USD-343,000USD-647,000USD-1,504,000USD123,350,000USD
    Change In Cash-7,435,000USD6,095,000USD-6,490,000USD2,744,000USD-664,000USD-3,595,000USD-2,591,000USD21,399,000USD
    Begin Period Cash Flow41,499,000USD35,607,000USD41,895,000USD39,352,000USD40,016,000USD43,611,000USD46,006,000USD24,607,000USD
    End Period Cash Flow34,064,000USD41,702,000USD35,405,000USD42,096,000USD39,352,000USD40,016,000USD43,415,000USD46,006,000USD
    Other Cashflows From Financing Activities-33,000USD-192,000USD-117,000USD-97,000USD-344,000USD-647,000USD-1,197,000USD-510,000USD
    Unclassified Operating Cash Flow-2,181,000USD—-3,911,000USD———-3,671,000USD-3,566,000USD
    Issuance Of Capital Stock—0USD0USD——0USD0USD—
    Unclassified Financing Cash Flow———————123,860,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Cash flow Yearly

    Exact reported values; units shown beside each amount. Missing values are —.
    MetricFY 20252025-12-31 · USDFY 20242024-12-31 · USDFY 20232023-12-31 · USDFY 20222022-12-31 · USDFY 20212021-12-31 · USDFY 20202020-12-31 · USD
    Net Income-77,905,000USD-80,556,000USD-60,388,000USD-31,167,000USD-16,243,000USD-5,306,000USD
    Depreciation919,000USD1,006,000USD536,000USD364,000USD37,000USD13,000USD
    Stock Based Compensation14,720,000USD14,288,000USD11,618,000USD2,185,000USD497,000USD3,000USD
    Other Non Cash Items1,027,000USD-2,845,000USD1,064,000USD33,000USD1,399,000USD2,170,000USD
    Change In Working Capital-2,426,000USD2,438,000USD8,138,000USD-1,532,000USD328,000USD317,000USD
    Total Cash From Operating Activities-63,665,000USD-65,669,000USD-42,641,000USD-30,117,000USD-13,982,000USD-2,803,000USD
    Capital Expenditures-1,669,000USD-2,768,000USD-1,288,000USD-2,166,000USD-238,000USD-15,000USD
    Free Cash Flow-65,334,000USD-68,437,000USD-43,929,000USD-32,283,000USD-14,220,000USD-2,818,000USD
    Investments67,769,000USD-51,771,000USD-64,886,000USD-139,510,000USD-238,000USD-15,000USD
    Total Cashflows From Investing Activities66,100,000USD-51,771,000USD50,717,000USD-141,676,000USD-238,000USD-15,000USD
    Total Cash From Financing Activities-749,000USD121,027,000USD-1,554,000USD101,709,000USD112,221,000USD2,889,000USD
    Issuance Of Capital Stock0USD69,997,000USD0USD104,458,000USD112,220,000USD2,831,000USD
    Change In Cash1,686,000USD3,587,000USD6,522,000USD-70,084,000USD98,001,000USD71,000USD
    Begin Period Cash Flow40,016,000USD36,429,000USD29,907,000USD99,991,000USD1,990,000USD1,919,000USD
    End Period Cash Flow41,702,000USD40,016,000USD36,429,000USD29,907,000USD99,991,000USD1,990,000USD
    Other Cashflows From Financing Activities-750,000USD51,030,000USD-1,297,000USD-2,749,000USD112,221,000USD2,831,000USD
    Unclassified Investing Cash Flow—2,768,000USD116,891,000USD———
    Unclassified Operating Cash Flow——-3,609,000USD———
    Change To Liabilities———-245,000USD798,000USD81,000USD
    Sale Purchase Of Stock———101,709,000USD——
    Cash And Cash Equivalents Changes———-70,084,000USD——
    Unclassified Financing Cash Flow———2,749,000USD-112,220,000USD-2,831,000USD
    Net Borrowings————0USD58,000USD
    SourceLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacyLegacy providerLegacy

    Operating metrics

    No operating metrics are currently published for this company.

    Revenue breakdown

    No revenue breakdown is currently published for this company.

    Periods follow company fiscal calendars. Quarterly, annual and year-to-date amounts are shown separately. Missing values are not zero. Data may be delayed, incomplete or corrected; follow the disclosure links to verify figures.